Undergraduate Research Internships in Pathobiology of Diabetic Nephropathy

糖尿病肾病病理学本科生研究实习

• 批准号: 9261216
• 负责人: BILLY GERALD HUDSON
• 金额: $ 9.56万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-30 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9261216
• 关键词: Undergraduate; Research; Internships; Pathobiology; Diabetic

DESCRIPTION (provided by applicant): There is a critical national need for educational innovations that recruit undergraduate students to pursue STEM (science, technology, engineering, mathematics) disciplines that fill the pipeline with scientists who conduct research in areas relevant to the NIH mission, and, in particular, that of NIDDK. Moreover, there is a dearth of STEM-oriented undergraduate students from whom to recruit into STEM careers, particularly those students from geographically- and economically-disadvantaged backgrounds and underrepresented racial and ethnic minority groups and Native Americans. Also, shortfalls in STEM achievement in K-12 students threaten the pipeline for entry of STEM undergraduates into advanced studies and the STEM workforce. These factors are major educational challenges that require innovations to overcome. The proposal seeks to help recruit, prepare and increase the numbers of undergraduate students that pursue STEM disciplines relevant to the NIDDK mission. We hypothesize that: 1) an intense research experience for undergraduate students involving crafting of questions, designing and conducting experiments, and presenting and arguing results will help develop their STEM acumen and recruit them into STEM careers; and 2) the research experience in diabetic nephropathy will help recruit them into STEM disciplines that serve as a foundation for investigation of renal biology and disease, and particularly diabetic renal disease. The proposal capitalizes on a 3-year pilot educational initiative, funded by a NIDDK ARRA supplemental grant, that established a novel AspirnautTM K-20 STEM pipeline (www.aspirnaut.org) for recruiting and developing diverse undergraduate and high school students for STEM careers. The research theme is the "Pathobiology of Diabetic Nephropathy". This theme is a primary research focus of the Division of Nephrology and the Center for Matrix Biology at Vanderbilt University Medical Center. The Specific Aims are: Aim 1. To provide research experience for 15 undergraduate students on the topic of "Pathobiology of Diabetic Nephropathy." Aim 2. To target 40% of participants to be underrepresented racial and ethnic groups and Native Americans and 70% from geographically- and economically-disadvantaged backgrounds. Aim 3. To teach 15 undergraduate students how to be mentors and inspirational role models for elementary and middle school students at rural schools. The outcomes are anticipated to help recruit increased numbers of undergraduates from disadvantaged and underrepresented groups into STEM disciplines of relevance to the NIDDK mission.

描述（由申请人提供）：国家迫切需要教育创新，招募本科生攻读 STEM（科学、技术、工程、数学）学科，填补在 NIH 使命相关领域（特别是 NIDDK 使命相关领域）进行研究的科学家的人才梯队。此外，缺乏适合 STEM 职业的面向 STEM 的本科生，特别是那些来自地理和经济弱势背景、代表性不足的种族和族裔群体以及美洲原住民的学生。此外，K-12 学生 STEM 成绩的不足威胁着 STEM 本科生进入高级研究和 STEM 劳动力队伍的渠道。这些因素是需要创新来克服的重大教育挑战。该提案旨在帮助招募、准备和增加攻读与 NIDDK 使命相关的 STEM 学科的本科生数量。我们假设：1）本科生丰富的研究经验（包括提出问题、设计和进行实验、展示和论证结果）将有助于培养他们的 STEM 敏锐度并吸引他们进入 STEM 职业； 2) 糖尿病肾病的研究经验将有助于将他们招募到 STEM 学科中，作为肾脏生物学和疾病（特别是糖尿病肾病）研究的基础。该提案利用了一项由 NIDDK ARRA 补充拨款资助的为期 3 年的试点教育计划，该计划建立了一个新颖的 AspirnautTM K-20 STEM 管道 (www.aspirnaut.org)，用于招募和培养多样化的本科生和高中生以从事 STEM 职业。研究主题是“糖尿病肾病的病理学”。该主题是范德比尔特大学医学中心肾病科和基质生物学中心的主要研究重点。具体目标是： 目标 1. 为 15 名本科生提供“糖尿病肾病病理学”主题的研究经验。目标 2. 目标是 40% 的参与者是代表性不足的种族和族裔群体以及美洲原住民，70% 的参与者来自地理和经济上处于不利地位的背景。目标3. 教导15名本科生如何成为农村学校中小学生的导师和励志榜样。预计研究结果将有助于招募更多来自弱势和代表性不足群体的本科生进入与 NIDDK 使命相关的 STEM 学科。