Measurement of Quality of Life and Perceived Disease Impact on Quality of Life in

生活质量的测量和感知疾病对生活质量的影响

• 批准号: 8693557
• 负责人: Sandra R Wilson
• 金额: $ 63.95万
• 依托单位: PALO ALTO MEDICAL FOUNDATION RES INST
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8693557
• 关键词: 18 year old; Adult; Adult asthma; Affect; American; Area; Asthma; Caring; Characteristics; Clinical Management; Clinical Research; Communities; Conduct Clinical Trials; Continuous Positive Airway Pressure; Data; Development; Dimensions; Disadvantaged; Disease; Educational workshop; Evaluation; Foundations; Guidelines; Health Policy; Health Status; Healthcare; Individual; Individual Differences; Intervention; Juniper; Knowledge; Life; Measurement; Measures; Mediating; Medical; Modeling; Observational Study; Outcome; Partner in relationship; Patient-Focused Outcomes; Patients; Perceived quality of life; Perception; Performance; Personal Satisfaction; Persons; Population Study; Property; Prospective Studies; Protocols documentation; Psychometrics; Pulmonary Function Test/Forced Expiratory Volume 1; Quality of life; Questionnaires; Randomized; Randomized Controlled Trials; Rattus; Recreation; Refractory; Research; Research Personnel; Respondent; Sampling; Social Sciences; Statistical Models; Structure; Symptoms; Testing; United States; United States National Institutes of Health; Walking; Weight; airway hyperresponsiveness; base; conventional therapy; follow-up; functional status; improved; instrument; intervention effect; meetings; novel; patient oriented; post intervention; prospective; psychologic; public health relevance; racial and ethnic; response; response marker; satisfaction; secondary outcome; social; tool; treatment effect

DESCRIPTION (provided by applicant): Existing asthma-related quality of life (QoL) scales do not directly assess QoL or the perceived impact of asth- ma on QoL. The purpose of this study is to evaluate the psychometric properties (reliability, concurrent and longitudinal validity, and responsiveness to change in asthma status) of a new measure of the patient- perceived negative effects of asthma in adults, the Asthma Impact on Quality of Life Scale (A-IQOLS), and to compare its properties with those of a measure of current QoL, the Flanagan Quality of Life Scale (QOLS). We hypothesize that the approach represented by the A-IQOLS will prove superior to that of the QOLS as an out- come measure for clinical research. This research can fill a significant gap in the currently available tools, with consequent benefit to asthma clinical research and, potentially, measurement of patient-centered outcomes in other disease areas.

描述(由申请人提供)：现有的哮喘相关生活质量(QOL)量表不直接评估QOL或哮喘对QOL的影响。本研究的目的是评估一种新的测量成人哮喘患者感知的负面影响的量表--哮喘对生活质量的影响量表(A-IQOLS)的心理测量学特性(信度、同时效度和纵向效度以及对哮喘状态变化的反应性)，并将其与当前的生活质量测量工具弗拉纳根生活质量量表(QOLS)的特性进行比较。我们假设，A-IQOLS所代表的方法将被证明优于QOLS作为临床研究的最终衡量标准。这项研究可以填补目前可用工具的一个重大空白，从而对哮喘临床有所裨益。 研究并潜在地衡量以患者为中心的其他疾病领域的结果。