UIC CENTERS FOR POPULATION HEALTH AND HEALTH DISPARITIES

UIC 人口健康和健康差异中心

• 批准号: 8703621
• 负责人: GARTH H RAUSCHER
• 金额: $ 20.64万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-30 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8703621
• 关键词: Address; Adherence; Affect; Benefits and Risks; Biological; Biological Factors; Breast Cancer Detection; Cancer Control; Centers for Population Health; Clinic; Color; Community Health; DNA Methylation; Diagnosis; Early Diagnosis; Ensure; Ethnic Origin; Evaluation; Funding; Genetic; Glass; Guidelines; Health Services Accessibility; Hospitals; Instruction; Intervention; Lead; Malignant Neoplasms; Mammography; Medically Underserved Area; Modeling; Monitor; National Cancer Institute; Outcome; Paper; Patient Monitoring; Patients; Policies; Population; Principal Investigator; Publications; Race; Research; Research Training; Risk; Staging; TNFRSF5 gene; Testing; Training; Underrepresented Minority; United States National Institutes of Health; Vision; Woman; Work; base; breast cancer diagnosis; cancer care; career development; data management; health disparity; improved; malignant breast neoplasm; multidisciplinary; outcome forecast; population health; programs; safety net; screening

Introduction: Current Aims and Center Theme. This proposal is for renewal of the UlC-Center for Population Health and Health Disparities (P50 CAI 0674). This Center is one of five that were funded in whole or in part by the National Cancer Institute as part of the initial NIH initiative. It is a Multiple Principal Investigator application. The center theme is: Understanding how our previous research identifying fundamental causes of disparities in stage at breast cancer diagnosis related to race/ethnicity can lead to interventions grounded in that research? The current aims of the proposed renewal of the Center are to address three questions that have emerged as central issues in understanding the disparity in stage at breast cancer diagnosis between White women and women of color based on our work to date. These are: I) To define how apparent disparities in early detection, diagnosis and treatment can be addressed in safety-net hospitals? 2a) Determine how community health clinics can more effectively identify and monitor patients at risk for aggressive breast cancer. 2b) Determine how patients at elevated risk can be engaged to participate in a tailored screening and monitoring program. 3) To determine how biological factors, specifically DNA methylation, promote aggressive breast cancer disproportionately among women of color? . There are three projects: .1) Patient Navigation in Medically Underserved Areas. (E. Calhoun, PI) 2) A Breast Cancer Screening Intervention to Improve Adherence to Cancer Control Guidelines in Underserved Minority Women (K. Hoskins, PI); DNA Methylation and Differential Cancer Aggressiveness by Race/Ethnicity (G. Rauscher, PI) and four cores: Administration (R. Warnecke (Contact) & E. Calhoun (Co- Core leaders); Policy and Dissemination (C. Ferrans, CL); Data Management and Evaluation (T. Johnson, (CL) and Training and Career Development (F Davis, CL ) Our continuing, long range vision is to test and establish interventions that address determinants of population health disparities by approaching them with a multilevel and multidisciplinary population health strategy. To accomplish this we will: 1) conduct research that impacts the policies that govern access to mammography and management of breast cancer and ensures equal access to the standard of breast cancer care regardless of where it is delivered and who requests it. 2) Enable women who are poor and underserved to recognize the need to access the care in ways that ensure the best outcomes. 3) To train young scholars in health disparities research incorporating a transdisciplinary research perspective.

导言：当前的目标和中心主题。本提案是对城市土地利用中心的更新。 人口健康与健康差距(P50 CAI0674)。该中心是五个由 全部或部分由国家癌症研究所作为NIH最初倡议的一部分。它是一个多重主体 调查员申请。中心主题是：理解我们之前的研究如何识别 与种族/民族有关的乳腺癌诊断阶段差异的根本原因可能导致 以该研究为基础的干预措施？拟议的中心更新目前的目标是 解决三个问题，这三个问题已成为理解阶段差距的核心问题 根据我们到目前为止的工作，白人女性和有色人种女性之间的乳腺癌诊断。这些 一)确定如何解决早期发现、诊断和治疗方面的明显差异 安全网医院？决定社区卫生诊所如何更有效地识别和监测 有患侵袭性乳腺癌风险的患者。2B)确定高风险患者如何参与 参加量身定做的筛查和监测计划。3)确定生物因素如何， 特别是DNA甲基化，在有色人种女性中不成比例地促进侵袭性乳腺癌？ 。有三个项目：1)在医疗服务不足的地区进行患者导航。(E.Calhoun，Pi)2)A 通过乳腺癌筛查干预提高贫困人群对癌症控制指南的遵从性 少数族裔妇女(K.Hoskins，PI)；DNA甲基化与分化癌症侵袭性 种族/族裔(G.Rauscher，Pi)和四个核心：管理(R.Warneke(联系人)和E.Calhoun(Co- 核心领导人)；政策和传播(C.Ferrans，CL)；数据管理和评估(T.Johnson， (CL)和培训和职业发展(F Davis，CL) 我们持续的长期愿景是测试和建立干预措施，以解决决定因素 用多层次、多学科的人口健康方法解决人口健康差距问题 策略。为了实现这一点，我们将：1)进行研究，以影响管理访问的政策 乳房X光检查和乳腺癌管理，确保平等获得乳房标准 癌症护理，无论在哪里提供，无论谁要求它。2)使贫穷和贫穷的妇女 服务不足，无法认识到需要以确保最佳结果的方式获得护理。3)培训 纳入跨学科研究视角的健康差距研究的年轻学者。