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Dealing with missing data in HIV prevention trials

Dealing with missing data in HIV prevention trials
处理艾滋病毒预防试验中缺失的数据
批准号:
8605221
负责人:
Ofer Harel
金额:
$17.22万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-04-09 至 2016-01-31
关键词:
AIDS preventionAIDS/HIV problemAccountingAcquired Immunodeficiency SyndromeAcyclovirAdultAfricanAfrican AmericanAgeAlcohol or Other Drugs useAlcoholsAmericanAttentionBehavior TherapyBehavioralBehavioral ResearchBiologicalBiometryCause of DeathCenters for Disease Control and Prevention (U.S.)CitiesClinicalCommunitiesComplicationCounselingCountryCross-Over StudiesDataDistrict of ColumbiaDouble-Blind MethodDropsEffectivenessEnsureEpidemicFundingFutureGoalsGuidelinesHIVHIV InfectionsHIV SeropositivityHIV prevention trialHIV prevention trials networkHIV-1HealthHealthcareHuman Herpesvirus 2InfectionIntentionInternationalInterventionIntervention StudiesInvestigationLeadLearningLifeLiteratureLongevityLongitudinal StudiesLos AngelesMeasuresMedicalMentored Research Scientist Development AwardMethodologyMethodsMissionNIH Program AnnouncementsNational Institute of Mental HealthNew YorkPersonsPharmaceutical PreparationsPlacebo ControlPlaguePopulationPositioning AttributePre-Post TestsPreventionPrevention ResearchPrevention programPreventive InterventionProceduresProcessQuality of lifeRampRandomizedRandomized Clinical TrialsResearchResearch DesignResearch PersonnelRiskRisk BehaviorsRisk ReductionSamplingSan FranciscoScienceScientistSimplexvirusSiteSouth AfricaTechniquesTestingTrainingUnited StatesUnited States National Institutes of HealthVariantVisitWomanWritingbasedesigneffective interventiongenital herpeshigh riskimprovedintravenous drug usemenmen who have sex with menpreventpublic health relevanceresponsesexsexually activesimulationsocialstatisticstooltransmission processtreatment effectvalacyclovir

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DESCRIPTION (provided by applicant): HIV/AIDS has been an international crisis for decades. All current research suggests that there is not likely to be any medical cure anytime soon, and that prevention is the best strategy that we can employ. However, notwithstanding that HIV/AIDS prevention has been the goal and primary focus of funding internationally for decades, we still see a sharp increase in the number of new HIV/AIDS cases across the globe annually. Clearly, there needs to be more focus and research dedicated to ensuring that we are using the best prevention techniques possible. My long term goal is to develop new methodologies for advancing clinical and community AIDS behavioral research. In addition, my aim is to develop new methods that will lead to enhanced HIV prevention interventions. This application supports the mission of the National Institute of Mental Health by providing methodologies for incomplete data, this will be used to help develop effective interventions and by providing training to position this candidate to engage in future research to improve the HIV prevention. PUBLIC HEALTH RELEVANCE: HIV/AIDS has been an international crisis for decades. All current research suggests that there is not likely to be any medical cure anytime soon, and that prevention is the best strategy that we can employ. My long term goal is to develop new methodologies for advancing clinical and community AIDS behavioral research. In addition, my aim is to develop new methods that will lead to enhanced HIV prevention interventions, In particular, methods to deal with incomplete data.
期刊论文(26)
专著(0)
科研奖励(0)
会议论文
Brief Report: Rethinking Data Collection for HIV Prevention Trials.
简要报告:重新思考艾滋病毒预防试验的数据收集。
DOI: 10.1097/qai.0000000000001005
发表时间: 2016
期刊: Journal of acquired immune deficiency syndromes (1999)
影响因子: --
作者: [Harel,Ofer, Nazzaro,Valerie]
通讯作者: Nazzaro,Valerie
A Review of Statistical Disclosure Control Techniques Employed by Web-Based Data Query Systems.
基于网络的数据查询系统所采用的统计披露控制技术的回顾。
DOI: 10.1097/phh.0000000000000473
发表时间: 2017
期刊: Journal of public health management and practice : JPHMP
影响因子: --
作者: [Matthews,GregoryJ, Harel,Ofer, AseltineJr,RobertH]
通讯作者: AseltineJr,RobertH
Analyzing clinical trial outcomes based on incomplete daily diary reports.
根据不完整的每日日记报告分析临床试验结果。
DOI: 10.1002/sim.6890
发表时间: 2016
期刊: Statistics in medicine
影响因子: 2
作者: [Thomas,Neal, Harel,Ofer, Little,RoderickJA]
通讯作者: Little,RoderickJA
The Use of Multiple Imputation for Data Subject to Limits of Detection.
对受检测限制的数据使用多重插补。
DOI: 10.4038/sljastats.v5i4.7792
发表时间: 2014
期刊: Sri Lankan journal of applied statistics
影响因子: --
作者: [Harel,Ofer, Perkins,Neil, Schisterman,EnriqueF]
通讯作者: Schisterman,EnriqueF
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    Dealing with missing data in HIV prevention trials
    Dealing with missing data in HIV prevention trials
    Dealing with missing data in HIV prevention trials
    Dealing with missing data in HIV prevention trials