Identification of TBK1 inhibitors in KRAS-dependent lung cancer
Identification of TBK1 inhibitors in KRAS-dependent lung cancer
批准号:
8844213
负责人:
William C. Hahn
金额:
$39.84万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
已结题
起止时间:
至 2016-04-30
关键词:
1-Phosphatidylinositol 3-KinaseAdverse effectsAllelesAnimal ModelAntibodiesBRCA1 geneBindingBiochemicalBiological ProcessBiologyCancer PatientCell DeathCell modelCellsChemistryClinicalConsensusDevelopmentERBB2 geneEpidermal Growth Factor ReceptorEpidermal Growth Factor Receptor Tyrosine Kinase InhibitorFoundationsGeneticGoalsHumanInvestigationKRAS2 geneLeadLung AdenocarcinomaMalignant NeoplasmsMalignant neoplasm of lungMammalian CellMediatingMutationNon-Small-Cell Lung CarcinomaOncogenesOncogenicPARP inhibitionPathway interactionsPhenotypePhospho-Specific AntibodiesPhosphotransferasesPropertyProtein KinaseProtein-Serine-Threonine KinasesProteinsProteomicsProto-OncogenesRNA InterferenceReceptor Protein-Tyrosine KinasesRefractoryResearch PersonnelRoleSignal PathwaySignal TransductionSiteStructureTechnologyTestingTherapeutic AgentsWorkbasechemotherapyclinically significantcytotoxicdrug developmentinhibitor/antagonistinsightmalignant breast neoplasmmutantnovel therapeuticsscreeningsmall moleculetheoriestherapeutic targettranslational studytumor
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依托单位:
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海外基金