A Culturally Adapted Depression Intervention for African American Adults

描述（由申请人提供）：非裔美国人深受抑郁症的困扰，但他们只有14%的时间得到适当的心理健康护理。最近一项文化适应干预（CAI）的荟萃分析表明，针对特定文化群体的干预措施比针对不同文化群体的干预措施有效四倍。不幸的是，专门针对非裔美国成年人的CAIs很少。“快乐日课程”（OHDC）是根据“应对抑郁课程”（CWD）的文化改编而成的，旨在治疗非裔美国成年人的抑郁症。我们建议采用两组（OHDC vs . CWD）随机对照试验和182名非洲裔美国成年人（30-55岁）的样本，在干预的基线、中期和立即结束以及干预后3、6、9和12个月进行测量。主要目标1：检查OHDC与CWD在提高保留率、依从性、参与度、满意度和寻求治疗方面的有效性。主要目的2：检查OHDC与CWD在减轻抑郁症状方面的有效性。次要目标3：检查OHDC与CWD相比在改善身心健康状况自我报告和减少残疾自我报告方面的有效性。公共卫生影响：根据CAI研究，OHDC的效力可能是CWD的四倍。如果我们的假设得到证实，OHDC将是第一个专门为非裔美国成年人设计的基于证据的文化适应抑郁症干预措施。

DESCRIPTION (provided by applicant): African Americans are burdened by depression, yet they receive adequate mental health care only 14% of the time. A recent meta-analysis of culturally adapted interventions (CAI) suggest interventions tailored to a specific cultural group were four times more effective than interventions provided to groups consisting of culturally diverse patients. Unfortunately, CAIs focusing specifically on African American adults are sparse. The Oh Happy Day Class (OHDC) was culturally adapted from the Coping with Depression Course (CWD) and designed to treat depression in African American adults. We propose using a two-group, (OHDC v. CWD) randomized controlled trial and a sample of 182 African American adults (age 30-55) with measures at baseline, middle and immediate end of the intervention and 3-, 6-, 9-, and 12-months post-intervention. Primary Aim 1: Examine effectiveness of the OHDC compared to the CWD in increasing retention, adherence, engagement, satisfaction, and treatment seeking. Primary Aim 2: Examine effectiveness of the OHDC compared to the CWD in reducing symptoms of depression. Secondary Aim 3: Examine the effectiveness of the OHDC compared to the CWD in improving self-report of mental and physical health status and reducing self-report of disability. Public Health Impact: Based on CAI research, the OHDC has the potential to be four times more effective than the CWD. If our hypotheses are proven, the OHDC will be the first evidence-based culturally adapted depression intervention designed specifically for African American adults.