Large-Scale Multi-Omic Analysis and Risk Prediction of Complex Human Disease

复杂人类疾病的大规模多组学分析和风险预测

• 批准号: nhmrc : 1090462
• 金额: $ 21.43万
• 依托单位: Baker IDI Heart and Diabetes Institute
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/large-scale-multi-human-disease/519287
• 关键词: Large; Scale; Multi; Omic; Analysis

A major aim of medicine is to prevent disease, which is often more successful and cost-effective than treating an already existing condition. Common diseases, such as autoimmune and cardiovascular diseases, have a predisposing genetic basis. We will conduct genetic analysis of large datasets of coeliac disease and cardiovascular disease to better identify individuals at increased risk and to better understand the underlying biological processes through which genetics act to affect one's risk.

医学的一个主要目的是预防疾病，这通常比治疗现有疾病更成功且更具成本效益。自身免疫性疾病和心血管疾病等常见疾病具有易感遗传基础。我们将对乳糜泻和心血管疾病的大型数据集进行遗传分析，以更好地识别风险增加的个体，并更好地了解遗传学影响个体风险的潜在生物过程。