Graduate Training Program in Neonatal-Perinatal Translational Research

新生儿-围产期转化研究研究生培训计划

• 批准号: 9038387
• 负责人: DAVID H ROWITCH
• 金额: $ 20.26万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2018-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9038387
• 关键词: Neonatal; Perinatal; Training Programs; Translational Research

DESCRIPTION (provided by applicant): This is an application for renewal of the Institutional Training Grant, "Graduate Research Training in Neonatal Translational Research." The goal of this interdisciplinary Program of the Department of Pediatrics at the University of California San Francisco (UCSF) is to provide comprehensive postdoctoral training and mentored career development for pediatricians with MD or MD, PhD degrees committed to an academic career with a strong component in "basic laboratory-to-human subjects (T1)" or "evidence-to-practice (T2)" research. This Program stems from a previous 30-year old NICHD-funded joint training program (Maternal-Fetal and Neonatal-Perinatal Medicine), in which >70% of graduates remain productive researchers and academic leaders in their respective fields. This application focuses on neonatologists-in-training, providing new and enhanced training opportunities in the neurosciences, stem cell biology, epidemiology and clinical investigation relevant to human development and neonatal disorders. The key elements of the proposed training are: (1) a mentored research experience, (2) scientific course work, (3) career development workshops, (4) interdisciplinary experiences and (5) continuing review and evaluation. The program provides two years of advanced research training for a total of three fellows. Thirty-four exceptionally well-qualified faculty members have committed their support as research mentors for this program that have combined NIH support of over 83 million dollars. All fellows will take courses in Responsible Conduct in Research, Scientific Writing and the Art of Lecturing. The fellow and research mentor determine additional course work in the specific field of research. A mentoring committee supports Fellows in setting and monitoring progress towards research and career goals. The Program Advisory Committee, comprising prominent UCSF investigators, active mentors and a distinguished External Reviewer, performs annual evaluation of all Fellows and the Program.

描述（由申请人提供）：这是一份机构培训补助金的续期申请，“新生儿转化研究的研究生研究培训”。加州大学旧金山分校（UCSF）儿科学系的这个跨学科项目的目标是为拥有医学博士或医学博士学位的儿科医生提供全面的博士后培训和指导的职业发展，这些儿科医生致力于在“基础实验室到人类受试者（T1）”或“证据到实践（T2）”的研究中有很强的组成部分。该项目源于30年前由美国儿童健康与发展中心资助的联合培训项目（母胎医学和新生儿围产期医学），其中70%的毕业生仍然是各自领域的富有成效的研究人员和学术领袖。该应用程序主要针对正在接受培训的新生儿科医生，在神经科学、干细胞生物学、流行病学和与人类发育和新生儿疾病相关的临床研究方面提供新的和增强的培训机会。拟议培训的关键要素是：(1)有指导的研究经验；(2)科学课程；(3)职业发展讲习班；(4)跨学科经验；(5)持续审查和评价。该项目为三名研究员提供了为期两年的高级研究培训。34名非常优秀的教师承诺作为研究导师支持这个项目，NIH总共支持了8300多万美元。所有研究员将学习研究中的负责任行为、科学写作和演讲艺术。研究员和研究导师确定在特定研究领域的额外课程。指导委员会支持研究员制定和监督研究和职业目标的进展。项目咨询委员会由著名的加州大学旧金山分校调查员、活跃的导师和一位杰出的外部审稿人组成，对所有研究员和项目进行年度评估。

项目成果

Effects of Prophylactic Indomethacin on Vasopressor-Dependent Hypotension in Extremely Preterm Infants.

• DOI: 10.1016/j.jpeds.2016.11.008
• 发表时间: 2017-03
• 期刊: The Journal of pediatrics
• 作者: Liebowitz M;Koo J;Wickremasinghe A;Allen IE;Clyman RI
• 通讯作者: Clyman RI

Invited commentary: does neonatal hyperbilirubinemia cause asthma?

特邀评论：新生儿高胆红素血症会导致哮喘吗？

• DOI: 10.1093/aje/kwt249
• 发表时间: 2013
• 期刊: American journal of epidemiology
• 影响因子: 5
• 作者: Kuzniewicz,MichaelW;Wickremasinghe,AndreaC;Newman,ThomasB
• 通讯作者: Newman,ThomasB

Dopamine-resistant hypotension and severe retinopathy of prematurity.

多巴胺抵抗性低血压和严重早产儿视网膜病变。

• DOI: 10.1016/j.jpeds.2013.01.054
• 发表时间: 2013
• 期刊: The Journal of pediatrics
• 作者: Catenacci,Melissa;Miyagi,Shogo;Wickremasinghe,AndreaC;Lucas,SarahScarpace;deAlbaCampomanes,AlejandraG;Good,WilliamV;Clyman,RonaldI
• 通讯作者: Clyman,RonaldI