RECQ2016 - Partnering for Progress

RECQ2016 - 合作共进

基本信息

批准号：
9122070
负责人：
RAYMOND J MONNAT
金额：
$ 0.8万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-04-01 至 2017-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9122070
关键词：
Address Affect Age Aging Area Award Basic Science Biology Caregivers Cells Clinical Research Clinical Sciences DNA Development Disease Education Family Family Caregiver Family member Fostering Foundations Fred Hutchinson Cancer Research Center Future Genome Stability Goals Health Human Human Biology Human Genome Individual International Knowledge Link Malignant Neoplasms Medicine Metabolism Mining Mission Participant Pathogenesis Patient Care Patient Education Patients Phenotype Physiological Play Positioning Attribute Predisposition Proteins Research Research Personnel Research Priority Research Support Role Rothmund-Thomson syndrome Science Scientist Structure Study models Support Groups Syndrome Training Translational Research Travel Update Work abstracting cancer type clinical care empowerment fascinate helicase high risk human DNA human disease improved interest loss of function meetings posters programs public health relevance symposium

项目摘要

DESCRIPTION (provided by applicant) Abstract: This application is to support the 3rd International Meeting on RECQ Helicases in Biology and Disease, titled 'RECQ2016 - Partnering for Progress', to be held at the Fred Hutchinson Cancer Research Center in Seattle, WA from Saturday 28 May to Monday 30 May 2016. The RECQ helicases play important roles in many aspects of human DNA metabolism and genomic stability, and are linked to Bloom, Werner and Rothmund- Thomson syndromes that all share a strong cancer predisposition. Goals: Our meeting goals are to improve understanding of RECQ helicase function in human cells; to deter- mine how the loss of RECQ function promotes cancer and other associated phenotypes; and to identify top clinical and research priorities to foster RECQ basic and translational research and improve clinical care. Aims: We will achieve our goals by addressing each of the following Aims/focus areas: Aim 1: Understand function and disease pathogenesis Aim 2: Develop research partnerships Aim 3: Identify research priorities Aim 4: Education - focused on patients, families and caregivers Aim 5: Training - focused on junior and new investigators and on clinicians Program Structure: We will convene 35 speakers/panelists, patients, family members, care givers and foundation/support groups for three focused and highly interactive days. There will be concurrent scientific presentations and Family meetings, with shared keynote talks, poster preview and poster sessions and panels. Significance: This conference is uniquely positioned to catalyze research by bringing together investigators focused on RECQ biology and disease with patients, families and caregivers. We aim to integrate basic and clinical science and incorporate the unique perspective of patients, families and caregivers in developing priorities for future work. Health relatedness: This meeting reflects the growing importance of RECQ helicases in human biology and disease, and the need to better understand the mechanistic origins of the RECQ helicase syndromes to understand disease associations and improve clinical care.

描述（应用程序提供）摘要：本申请是为了支持第三次国际RECQ解放酶在生物学和疾病中的RECQ解旋酶，标题为“ RECQ2016-2016-进步伙伴”，将于2016年5月28日星期六至2016年5月28日星期六在华盛顿州西雅图的Fred Hutchinson Cancer Research Center举行Rothmund- Thomson综合征都具有强烈的癌症易感性。目标：我们的会议目标是提高对人类细胞中RECQ解旋酶功能功能的理解；确定RECQ功能的丧失如何促进癌症和其他相关的表型；并确定最高的临床和研究优先级，以培养RECQ基础和翻译研究并改善临床护理。目的：我们将通过解决以下每个目标/焦点领域来实现目标：目标1：了解功能和疾病发病机理目标2：发展研究伙伴关系目标3：确定研究优先级目标目标4：教育 - 专注于患者，家庭和看护者的目标5：培训5：培训 - 专注于初级和新研究人员，以及新的研究人员以及新的研究人员以及临床机构的临床机构和临床组合的人，我们将召集三分之二的人，我们将召集了5555名兼职，555555岁，我们将兼职5555名兼职555555岁。互动日。将有同时进行的科学演讲和家庭会议，并举办共同的主题演讲，海报预览和海报会议和小组。意义：这次会议是通过与患者，家庭和看护者一起关注RECQ生物学和疾病的研究人员将研究人员汇集在一起的独特定位。我们旨在整合基础和临床科学，并将患者，家庭和照顾者的独特视角纳入未来工作的重点。健康相关性：这次会议反映了RECQ解旋酶在人类生物学和疾病中的重要性，并且需要更好地了解RECQ解旋酶综合征的机械起源，以了解疾病关联并改善临床护理。