Influence of Auditory Stimulation on Anxiety in Weaning from Mechanical Ventilation

听觉刺激对机械通气撤机焦虑的影响

• 批准号: 8915982
• 负责人: Breanna D Hetland
• 金额: $ 0.34万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2015-08-07
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8915982
• 关键词: Accounting; Acid-Base Equilibrium; Acoustic Stimulation; Acute; Address; Analgesics; Anxiety; Caring; Client satisfaction; Clinical; Complement; Conscious; Control Groups; Critical Illness; Data; Data Analyses; Delirium; Edema; Environmental air flow; Evaluation; Failure; Fatigue; Goals; Hospitals; Intensive Care Units; Intervention; Investigation; Knowledge; Lead; Length; Length of Stay; Life; Linear Regressions; Mechanical ventilation; Mechanics; Medical; Mental Depression; Modality; Morbidity - disease rate; Muscle Weakness; Music; Neurological status; Pain; Parents; Pathological anxiety; Patients; Pharmaceutical Preparations; Physiological; Post-Traumatic Stress Disorders; Process; Quality of life; Randomized Controlled Clinical Trials; Randomized Controlled Trials; Recovery; Recruitment Activity; Research; Respiratory Failure; Respiratory Muscles; Risk; Secondary to; Sedation procedure; Site; Sleep disturbances; Strategic Planning; Survival Analysis; Sympathetic Nervous System; Symptoms; Time; Training; Trauma; Ventilator; Ventilator Weaning; Weaning; Work of Breathing; anxiety management; base; clinical practice; conventional therapy; cost; deconditioning; evidence base; experience; hazard; innovation; mortality; muscle strength; nutrition; psychologic; public health relevance; respiratory; sedative; success; symptom management; ventilator-associated pneumonia

DESCRIPTION (provided by applicant): Many ICU patients require mechanical ventilation (MV) which can cause consistent high levels of anxiety and increase the risk of complications, as well as lead to longer lengths of hospital stays and higher rates of morbidity and mortality. Generally, as patients recover from acute illness, they can be "weaned" off of the ventilator. Weaning is a gradual decrease in ventilator settings that leads to liberation from mechanical ventilatory support. Anxiety is a major psychological issue experienced during MV and during the MV weaning process. Music intervention is one integrative therapy shown to decrease pain and anxiety during MV. Incorporating music into the care of the mechanically ventilated patient has strong potential to alleviate the symptom burden and the high cost of conventional treatments, as well as increase patient satisfaction and promote efficient weaning. Little research has been conducted to evaluate the impact of music on ventilator weaning trials. While music has been studied previously in MV patients, a large knowledge gap exists regarding music's influence during ventilator weaning trials. Further evaluation of music intervention during weaning trials is essential to determine if this adjunctive therapy can reduce anxiety during weaning trials and promote efficient ventilator liberation. Incorporating music during ventilator weaning trials is an innovative idea that warrants more thorough investigation. The proposed research is a secondary analysis of data from the primary sponsor's R01-NR009295 (L.Chlan, PI) using exploratory survival analysis, a proportional hazards regression, and linear regression. This project is significant because of the potential clinical benefit to ventilated patients. It wil provide an in-depth analysis of the influence of anxiety on ventilator weaning trials as well as th effect of music on anxiety during mechanical ventilator weaning trials by evaluating objective data originally obtained through a large randomized controlled clinical trial. The knowledge gained from this study will advance current practices of anxiety management during weaning trials in mechanically ventilated patients. This study is consistent with NINR's 2011 Strategic Plan to advance the quality of life through symptom management during acute illness. The findings will provide new information regarding the influence of anxiety during weaning from MV and the potential impact of music on anxiety during weaning from MV. The knowledge obtained through activities proposed in this training plan has the potential to lead to innovative perspectives and strategies for medical management of the mechanically ventilated patient, as well as build the evidence base supporting the use of integrative therapies as viable adjuncts in the care of the estimated 5 million patients who experience acute critical illness each year.

描述（由申请人提供）：许多ICU患者需要机械通气（MV），这可能导致持续的高度焦虑，增加并发症的风险，并导致住院时间更长，发病率和死亡率更高。一般来说，当病人从急性疾病中恢复过来时，他们可以“断奶”呼吸机。脱机是指呼吸机设置逐渐减少，从而从机械通气支持中解放出来。焦虑是在MV和MV脱机过程中经历的主要心理问题。音乐干预是一种综合疗法，可以减少MV中的疼痛和焦虑。将音乐融入机械通气患者的护理中，在减轻常规治疗的症状负担和高昂费用、提高患者满意度和促进高效脱机方面具有很大的潜力。很少有研究评估音乐对呼吸机脱机试验的影响。虽然音乐之前在MV患者中进行过研究，但关于音乐在呼吸机脱机试验中的影响存在很大的知识差距。音乐干预的进一步评价