Indiana Diabetes Research Center

 描述(申请人提供)：这份P30申请书代表了印第安纳大学医学院(IUSM)多年来努力建设其糖尿病和肥胖症研究基地并专注于代表国家优先领域的特定基础科学和翻译研究主题的成果。这项申请的一个重要组成部分是包括附近普渡大学的合作研究人员，他们在肥胖、营养和生物医学工程方面的项目是对IUSM研究主题的补充。对P30应用程序的支持将通过提供专门的资源来支持印第安纳州的糖尿病研究，该资源允许糖尿病研究和教育活动集中并集中在我们研究基地的基本主题上，补贴研究核心服务以鼓励将其用于创新和翻译，并允许为新的研究人员提供创新研究支持，以维持一支才华横溢的糖尿病研究人员队伍。印第安纳州糖尿病研究中心(IDRC)的使命是培养知识，支持培训，并促进糖尿病和相关代谢紊乱及其并发症的基础和翻译研究。IDRC由印第安纳大学医学院和附近普渡大学的研究员组成的研究基地组成，这些研究将共同增加5个最先进的研究核心(胰岛、啮齿动物、显微镜、猪和翻译核心)。一个由5个T32培训补助金支持的丰富计划将促进学习和发现。一个试点和可行性计划将通过向非常有前途的年轻研究人员提供资金来扩大研究基地。一个行政核心将监督IDRC的治理，并将从执行委员会、内部咨询委员会和由世界知名的糖尿病/新陈代谢研究领导者组成的外部咨询委员会获得意见。国际糖尿病研究中心的目标将是(1)通过建立研究核心，促进合作和使用先进的方法和人体研究，促进有影响力的科学发现；(2)加强一个高度协作的环境，促进学习和鼓励研究人员之间的互动；(3)支持培训和创新研究人员，培养一批新兴的优秀研究人员，有可能成为未来糖尿病研究的领导者；(4)建立和加强糖尿病研究基地，支持基础设施，以确保持续的增长和创新，并与当地社区接触，提高对糖尿病的认识和参与。

 DESCRIPTION (provided by applicant): This P30 application represents the culmination of years of an Indiana University School of Medicine (IUSM) effort to build its diabetes and obesity research base and to focus on specific basic science and translational research themes that represent areas of national priority. An important component of this application is the inclusion of collaborative researchers at nearby Purdue University, whose programs in obesity, nutrition, and biomedical engineering are complementary to the research themes at IUSM. Support of this P30 application will bolster diabetes research in Indiana by providing a dedicated resource that allows diabetes research and educational activities to be centralized and focused on the fundamental themes of our Research Base, that subsidizes Research Core services to encourage their use for innovation and translation, and that permits innovative research support for new investigators to maintain a pipeline of talented diabetes-oriented researchers. The mission of the Indiana Diabetes Research Center (IDRC) is to foster knowledge, support training, and promote basic and translational research in diabetes and related metabolic disorders, and their complications. The IDRC consists of a Research Base of 64 highly collaborative investigators at Indiana University School of Medicine and nearby Purdue University, whose research collectively will be augmented by 5 state-of-the-art Research Cores (Islet, Rodent, Microscopy, Swine, and Translation Cores). An Enrichment Program, supported by 5 T32 training grants, will enhance learning and discovery. A Pilot and Feasibility Program will grow the Research Base by providing funding to highly promising young investigators. An Administrative Core will oversee governance of the IDRC, and will receive input from an Executive Committee, an Internal Advisory Board, and an External Advisory Board of world-renowned diabetes/metabolism research leaders. The Aims of the IDRC will be to (1) Promote high impact scientific discoveries by establishing Research Cores that facilitate collaborations and the use of state-of-the-art methodologies and human studies in diabetes research; (2) Enhance a highly collaborative environment that promotes learning and encourages interaction among investigators; (3) Support the training and innovative research of a burgeoning pool of superb investigators with the potential to become future leaders in diabetes research; (4) Build and strengthen the diabetes research base, support infrastructure to ensure ongoing growth and innovation, and engage with the local community to raise diabetes awareness and involvement.