Administrative Core

项目摘要-行政核心 行政核心将监督P01赠款的行政和财务活动。整体 行政核心的目标是提供集中的科学、行政和财政 管理和监督我们的计划项目（P01）授予题为“功能基因组学和DEC-Tec， 确定生殖细胞特异性避孕药。”行政核心将1）促进内部的科学互动 P01资助团队以及我们的P01团队和其他在避孕领域工作的研究人员之间，2） 领导P01研究人员保持高质量，成功的研究和核心活动，并履行其 具体的宗旨和目标，以及3）促进可逆性男女避孕药具的运动， 临床试验行政核心将为跟踪赠款资金的使用情况提供支持， 与P01相关的报告和未来的赠款提交。Martin M.博士Matzuk将是主要的 负责行政核心的个人，将提供行政和科学管理， P01补助金，并负责决定与研究优先次序或问题有关的政策事宜 项目或核心内以及P01赠款的整体运作。研究咨询 委员会（多学科内部和外部科学和行政成员和领导人）将 为Matzuk博士、项目和核心提供建议和指导。Matzuk博士将每月由 业务委员会关于小组内资源分配和资金支付的具体情况 用于额外或替换人员、设备或其他需要。行政核心将协调 研究咨询委员会（RAC）年会。RAC将指导每个项目， DEC-Tec核心，关于选定的避孕目标的“执行”与“不执行”的决定， 筛查和小分子避孕药开发项目。此外，行政核心将 协调RAC的半年度电话会议。行政支助将由两名 有才华的专业人士。Dr. John W.纳尔逊，在药物发现中心的业务经理，和女士。 Veronica阿吉拉尔，高级赠款专家，将提供多种行政和财务管理 服务行政核心将位于贝勒Cullen大楼二楼，交通便利。 医学院（ESTA）靠近ESTA项目研究者。所有项目负责人和核心 董事，包括大坂大学的董事，将有机会获得财务，人事，网络， 计算机服务。三个项目和核心B（DEC-Tec）将平等地利用行政核心。的 管理核心和RAC将指导P01项目和核心领导人做出关键决策， 或停止每一项避孕开发运动，并将大大有助于这一P01的成功 赠款提案和创造多种新型生殖细胞特异性避孕药。

PROJECT SUMMARY - ADMINISTRATIVE CORE The Administrative Core will oversee the administrative and financial activities of the P01 grant. The overall objective of the Administrative Core is to provide centralized scientific, administrative, and financial management and oversight of our program project (P01) grant entitled “Functional genomics and DEC-Tec to identify germ cell–specific contraceptives.” The Administrative Core will 1) foster scientific interactions within the P01 grant team and between our P01 team and other investigators working in the field of contraception, 2) lead the P01 investigators to maintain high-quality, successful research and core activities and fulfill their Specific Aims and objectives, and 3) promote the movement of reversible male and female contraceptives into clinical trials. The Administrative Core will provide support for tracking grant fund utilization and prepare all reports and future grant submissions associated with the P01. Dr. Martin M. Matzuk will be the primary individual responsible for the Administrative Core, will provide administrative and scientific management of the P01 grant, and will be responsible for decisions regarding policy matters relating to research priorities or issues within the Projects or Cores as well as the overall operation of the P01 grant. The Research Advisory Committee (multidisciplinary internal and external scientific and administrative members and leaders) will provide advice and direction to Dr. Matzuk, Projects, and Cores. Dr. Matzuk will be advised monthly by the Operations Committee regarding the specifics of resource allocation within the group and fund disbursement for additional or replacement personnel, equipment, or other needs. The Administrative Core will coordinate the annual meeting of the Research Advisory Committee (RAC). The RAC will guide each Project and the DEC-Tec Core on decisions of “Go” versus “No Go” for the contraceptive targets chosen, follow-up targets to screen, and the small-molecule contraceptive development program. Additionally, the Administrative Core will coordinate a semi-annual conference call meeting of the RAC. Administrative support will be furnished by two talented professionals. Dr. John W. Nelson, Business Manager in the Center for Drug Discovery, and Ms. Veronica Aguilar, a Senior Grants Specialist, will provide multiple administrative and financial management services. The Administrative Core will be conveniently located on the 2nd floor of the Cullen Building at Baylor College of Medicine (BCM) in close proximity to the BCM Project Investigators. All Project Leaders and Core Directors, including those at Osaka University, will have access to financial, personnel, networking, and computer services. The three Projects and Core B (DEC-Tec) will utilize the Administrative Core equally. The Administrative Core and RAC will guide the P01 Project and Core Leaders on critical decisions for advancing or halting each contraceptive development campaign and will contribute significantly to the success of this P01 grant proposal and the creation of multiple novel germ cell-specific contraceptives.