Local Sleep in the Awake Brain: An Underlying Cause of Neurobehavioural Deficits in Sleep Apnea?

清醒大脑中的局部睡眠：睡眠呼吸暂停神经行为缺陷的根本原因？

• 批准号: nhmrc : GNT1144601
• 负责人: A/Pr Craig Phillips
• 金额: $ 58.23万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/local-sleep-awake-sleep-apnea/1348621
• 关键词: Local; Sleep; Awake; Brain; Underlying

Obstructive sleep apnea (OSA) is a common sleep disorder which significantly impacts daytime functioning leading to excessive sleepiness, and problems with attention and thinking. Currently, the causes for cognitive impairment in OSA (including attentional lapses and performance deficits) are poorly understood. In the awake state, groups of neurons can briefly go “offline” as they do in sleep. These periods of “local sleep” may explain impaired task performance in OSA.

阻塞性睡眠呼吸暂停 (OSA) 是一种常见的睡眠障碍，会严重影响白天的功能，导致过度嗜睡以及注意力和思维问题。目前，人们对 OSA 认知障碍（包括注意力缺失和表现缺陷）的原因知之甚少。在清醒状态下，神经元群可以像睡眠时一样短暂地“离线”。这些“局部睡眠”时期可能可以解释 OSA 任务表现受损的原因。