Localising epileptic discharges in the brain using non-invasive electro-magnetic signal analysis in patients with difficult-to-control epilepsy

使用非侵入性电磁信号分析对难以控制的癫痫患者进行脑部癫痫放电定位

• 批准号: nhmrc : GNT1054520
• 负责人: Dr Chris Plummer
• 金额: $ 11.99万
• 依托单位: Swinburne University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/localising-epileptic-discharges-control-epilepsy/1344571
• 关键词: Localising; epileptic; discharges; brain; using

Epilepsy is a leading cause of chronic morbidity in Australia. A fundamental problem in clinical practice is the accurate identification of the 'hotspot' zone in the brain that is generating epileptic discharges. These discharges can be detected non-invasively (over the scalp) and analysed with electro-encephalographic and magneto-encephalographic source localisation (EMSL) techniques. EMSL is not used in routine clinical practice because we await a large scale prospective study (the aim of this proposal).

在澳大利亚，癫痫是慢性发病率的主要原因。临床实践中的一个基本问题是准确识别大脑中产生癫痫放电的“热点”区域。这些放电可以非侵入性地(在头皮上)检测到，并使用脑电和脑磁图来源定位(EMSL)技术进行分析。EMSL没有用于常规的临床实践，因为我们正在等待一项大规模的前瞻性研究(这项建议的目的)。