Using an API to commercialize an evidence-based weight loss intervention

使用 API 将基于证据的减肥干预措施商业化

• 批准号: 9265086
• 负责人: Shawna E Doerksen
• 金额: $ 45.4万
• 依托单位: COEUS HEALTH, LLC
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-15 至 2020-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9265086
• 关键词: Address; Behavioral; Blood Pressure; Body Weight decreased; C-reactive protein; Cellular Phone; Chronic Disease; Clinical; Computer software; Devices; Diet; Disease Management; Effectiveness; Electronic Health Record; Employee; Evidence based intervention; Glucose; Health; Health Risk Appraisals; Heart Diseases; Insurance Carriers; Intervention; Investigation; Language; Lipids; Location; Malignant Neoplasms; Manufacturer Name; Metabolic syndrome; Modernization; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Online Systems; Outcome; Overweight; Participant; Patients; Phase; Physical activity; Plasma; Population; Process; Randomized Clinical Trials; Randomized Controlled Trials; Research; Research Personnel; Resources; Risk Marker; Sampling; Services; Software Design; Testing; Text; Time; Translating; Translations; Vendor; Virtual Tool; Weight; Weight maintenance regimen; Work; application programming interface; attentional control; base; cardiometabolic risk; commercial application; commercialization; cost; cost effective; design; digital; effective intervention; effectiveness clinical trial; evidence base; experience; health application; mobile application; movie; psychosocial; public health relevance; theories; tool; usability; web app; weight loss intervention

DESCRIPTION (provided by applicant): Over 69 percent of the U.S. population is currently overweight or obese; 35 percent are obese. Obesity is a primary cause of numerous chronic diseases including type II diabetes, cancer, heart disease and the metabolic syndrome. Behavioral weight loss interventions have successfully resulted in significant clinical improvements in weight (7-10 percent weight loss) that is sustained for at least 6-12 months. Unfortunately, such interventions are often time consuming, resource intensive and difficult to scale. Digital health holds enormous promise for addressing weight loss and several trials have shown meaningful weight loss using digital health tools. Digital health provides a means of reaching large numbers of people with highly personalized content and sustained long-term participant engagement -all at low cost. Despite the promise, digital health has not delivered. Evidence-based tools are virtually absent from the commercial digital health space. This application creates a new commercial market segment for digital health - health application programming interfaces. An API is a way for software applications to talk to one another in a language that they both understand. APIs are efficient, cost effective, and ubiquitous in the commercial market. The API allows us to disseminate evidence based interventions in an efficient, cost-effective manner. APIs allow us to disseminate effective interventions in developer's "language," while preserving the interventions' theoretical and evidentiary basis. APIs are used anywhere that software is used, so they will allow us to reach varied health market segments including app developers, disease management firms, health insurers and employee wellness firms. In Phase I, we will create a commercial weight loss API (WeightBox) that builds on an existing evidence based framework and evaluate its usability. In Phase II, we will test the effectiveness of a mobile app that uses the WeightBox API in a randomized clinical trial. At the end of Phase II, our API (and proof-of-principle app) might be the only digital healt weight loss tools in the market with clinical trial effectiveness evidence.

描述（由申请人提供）：目前超过 69% 的美国人口超重或肥胖； 35% 的人肥胖。肥胖是许多慢性疾病的主要原因，包括二型糖尿病、癌症、心脏病和代谢综合征。行为减肥干预措施已成功实现体重的显着临床改善（体重减轻 7-10%），且可持续至少 6-12 个月。不幸的是，此类干预措施往往耗时、资源密集且难以扩展。数字健康对于解决减肥问题有着巨大的前景，多项试验已经表明，使用数字健康工具可以有效地减轻体重。数字健康提供了一种以高度个性化的内容和持续的长期参与者参与接触大量人群的方法，而且成本低廉。尽管做出了承诺，但数字医疗尚未兑现。商业数字健康领域实际上不存在基于证据的工具。该应用程序为数字健康创造了一个新的商业细分市场——健康应用程序编程接口。 API 是软件应用程序以双方都能理解的语言相互通信的一种方式。 API 高效、经济且在商业市场中无处不在。 API 使我们能够以高效、具有成本效益的方式传播基于证据的干预措施。 API 使我们能够以开发人员的“语言”传播有效的干预措施，同时保留干预措施的理论和证据基础。 API 可用于任何使用软件的地方，因此它们将使我们能够进入不同的健康细分市场，包括应用程序开发商、疾病管理公司、健康保险公司和员工健康公司。在第一阶段，我们将创建一个商业减肥 API (WeightBox)，该 API 建立在现有的基于证据的框架之上，并评估其可用性。在第二阶段，我们将在随机临床试验中测试使用 WeightBox API 的移动应用程序的有效性。在第二阶段结束时，我们的 API（和原理验证应用程序）可能是市场上唯一具有临床试验有效性证据的数字健康减肥工具。