Multiplexing biomarker analyzer

 描述（由申请人提供）：本申请请求支持购买 Luminex 100/200，该系统利用基于珠子的检测技术分析实验样品（裂解物、血清、组织）中的 900 多种单独分析物。 Luminex 100/200 仪器允许研究人员对蛋白质或核酸生物标志物进行多重分析和小型化分析，从而提高数据质量、通量和成本效益。集中这些研究并提供各种分析物的最先进的高通量检测的机会将最大限度地减少成本和时间，同时最大限度地提高产量。本申请中详述的 9 个 NIH 资助实验室的具体项目在其科学兴趣上差异很大，但它们都有一个共同目标，即在患者样本或疾病实验室模型的背景下追求转化终点。

 DESCRIPTION (provided by applicant): This application requests support for the purchase of a Luminex 100/200, a system that analyzes experimental samples (lysates, serum, tissues) for over 900 individual analytes utilizing a bead-based detection technology. The Luminex 100/200 instrument allows investigators to multiplex and miniaturize assays of either protein or nucleic acid biomarkers increasing data quality, throughput and cost effectiveness. The opportunity to centralize these studies and provide state-of-the-art high-throughput assays of a variety of analytes will minimize cost and time, while maximizing output. The specific projects of the 9 NIH funded laboratories detailed within this application vary widely in their scientific interests, however they share the common goal of pursuing translational endpoints within the context of patient samples or laboratory models of disease.