Multiplexing biomarker analyzer

多重生物标志物分析仪

• 批准号: 9075947
• 负责人: ERICA A. GOLEMIS
• 金额: $ 7.59万
• 依托单位: RESEARCH INST OF FOX CHASE CAN CTR
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-03-01 至 2017-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9075947
• 关键词: Biological Assay; Biological Markers; Data Quality; Detection; Disease model; Funding; Goals; Individual; Laboratories; Nucleic Acids; Output; Patients; Proteins; Request for Applications; Research Personnel; Sampling; Serum; Systems Analysis; Technology; Time; Tissues; United States National Institutes of Health; base; cost; cost effectiveness; high throughput screening; instrument; interest; miniaturize

 DESCRIPTION (provided by applicant): This application requests support for the purchase of a Luminex 100/200, a system that analyzes experimental samples (lysates, serum, tissues) for over 900 individual analytes utilizing a bead-based detection technology. The Luminex 100/200 instrument allows investigators to multiplex and miniaturize assays of either protein or nucleic acid biomarkers increasing data quality, throughput and cost effectiveness. The opportunity to centralize these studies and provide state-of-the-art high-throughput assays of a variety of analytes will minimize cost and time, while maximizing output. The specific projects of the 9 NIH funded laboratories detailed within this application vary widely in their scientific interests, however they share the common goal of pursuing translational endpoints within the context of patient samples or laboratory models of disease.

 描述（由申请人提供）：本申请请求支持购买Luminex 100/200，Luminex 100/200是一种利用基于微珠的检测技术分析实验样本（裂解物、血清、组织）中超过900种单独分析物的系统。Luminex 100/200仪器允许研究人员对蛋白质或核酸生物标志物进行多重和重复测定，从而提高数据质量、通量和成本效益。集中这些研究并提供各种分析物的最先进的高通量测定的机会将最大限度地减少成本和时间，同时最大限度地提高产量。本申请中详述的9个NIH资助实验室的具体项目在其科学兴趣方面差异很大，但它们都有一个共同的目标，即在患者样本或疾病实验室模型的背景下追求转化终点。