Texting intervention to sustain HIV prevention in women in high-drug-use contexts

短信干预以维持高吸毒环境中女性的艾滋病毒预防

基本信息

项目摘要

 DESCRIPTION (provided by applicant): Treatment effects of health behavior interventions erode, often with relapse rates greater than 50% within 6 months, perhaps because the constructs that sustain behavior change differ from those that favor behavior acquisition. The overarching aim of this study is to evaluate the efficacy of Mujer Segura Siempre (MSS, Always Healthy Woman), a safer-sex behavior maintenance intervention delivered by means of tailored text messaging. MSS will use theory-based, individually tailored text messages that are designed to maintain the positive effects of an evidence-based counseling intervention (Mujer Más Segura, R01 DA023877) that was shown to be efficacious in reducing HIV/STI incidence by more than 60% among both drug-using and non- drug-using female sex workers (FSWs) in Tijuana and Ciudad (Cd.) Juarez, Mexico. The content of the text messages will be based on constructs from behavior-maintenance theory. Our specific aims are to: (1) deter- mine if the theory-based MSS text-messaging intervention is associated with the long-term (24-month) mainte- nance of significant reductions in HIV/STI incidence (primary outcome) among drug-using and non-drug-using FSWs in Tijuana and Cd. Juarez relative to a time-equivalent control condition; (2) determine if the MSS intervention is associated with greater reductions in unprotected vaginal and anal sex with male clients, better attendance at regularly scheduled STI screenings, and reduced sharing of drug paraphernalia for FSW-IDUs (secondary outcomes) relative to a time-equivalent control condition; (3) determine if substance use factors (frequency, intensity, and patterns of alcohol and drug use) mediate or moderate the efficacy of the interven- tion, taking into account environmental risk factors (e.g., drugs in the workplace), maintenance constructs (e.g., maintenance self-efficacy), and personal characteristics (e.g., age, sexual abuse, depression); and (4) evalu- ate the cost-effectiveness of MSS compared to the control condition, to Mujer Más Segura alone (data from previous studies), and to usual care in Mexico. To meet these aims, we will deliver the brief Mujer Más Segura counseling intervention to 600 HIV-negative FSWs (300 in Tijuana, 300 in Cd. Juarez) who report unsafe sex with at least one client in the previous 6 months, and randomize them to either Group 1 (n=300), the MSS text- messaging maintenance program for 24 months post-counseling (since relapse is most likely to occur within this period) or Group 2 (control condition, n=300), general health text messages for 24 months post-counsel- ing. Both groups will undergo follow-up behavioral assessments and STI testing at 6, 12, 18, and 24 months. This study will advance the use of commonly available information technology to empower high-risk women in lower- to middle-income countries (LMICs) to prolong the benefit of an efficacious HIV prevention intervention. It also addresses the goals of the Office of Research on Women's Health to incorporate gender into the design and development of new technologies for HIV prevention among high-risk women, and to personalize prevention messages that will maintain positive behavioral change.
 描述(申请人提供):健康行为干预的治疗效果受到侵蚀,通常在6个月内复发率超过50%,可能是因为维持行为改变的结构与有利于行为习得的结构不同。这项研究的主要目的是评估Mujer Segura Siempre(MSS,Always Healthy女性)的疗效,这是一种通过定制短信传递的安全性行为维持干预措施。MSS将使用基于理论的、个性化的短信,旨在保持循证咨询干预(Mujer MáS Segura,R01 DA023877)的积极效果,该干预被证明有效地将提华纳和Ciudad(CD)吸毒和非吸毒女性性工作者(FSWs)的艾滋病毒/性传播感染发病率降低了60%以上。墨西哥华雷斯。短信的内容将基于行为维持理论的结构。我们的具体目标是:(1)确定基于理论的MSS短信干预是否与提华纳和CD吸毒者和非吸毒者HIV/STI发病率(主要结果)的长期(24个月)显著下降有关。与时间相同的控制条件相比,(2)确定MSS干预是否与更大程度地减少与男性客户的无保护的阴道和肛门性行为,更好地参加定期安排的性传播感染筛查,以及相对于时间相同的控制条件减少FSW-IDU的药物用具共享(二次结果)有关;(3)确定药物使用因素(频率, (4)评估MSS与对照条件、Mujer MáS Segura单独使用(来自先前研究的数据)以及墨西哥的日常护理相比的成本效益。为了实现这些目标,我们将向600名艾滋病毒阴性性工作者(提华纳300人,CD 300人)提供简短的Mujer MáS Segura咨询干预。华雷斯)报告在过去6个月内与至少一个客户发生不安全性行为的人,并将他们随机分为咨询后24个月的MSS短信维护计划(因为在这段时间内最有可能复发)或咨询后24个月的一般健康短信。两组都将在6个月、12个月、18个月和24个月时接受后续行为评估和STI测试。这项研究将推进普遍可用的信息技术的使用,以增强中低收入国家的高危妇女的能力,延长有效的艾滋病毒预防干预措施的益处。它还涉及妇女健康研究办公室的目标,即将性别问题纳入在高危妇女中预防艾滋病毒的新技术的设计和开发中,并使预防信息个性化,以保持积极的行为变化。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Thomas L. Patterson其他文献

Family Conflict and Depressive Symptoms: A Study of HIV-Seropositive Men
  • DOI:
    10.1023/a:1026265921872
  • 发表时间:
    1997-03-01
  • 期刊:
  • 影响因子:
    2.400
  • 作者:
    Shirley J. Semple;Thomas L. Patterson;Lydia R. Temoshok;Kristy Straits-Tröster;J. Hampton Atkinson;William Koch;Igor Grant
  • 通讯作者:
    Igor Grant
Estimaciones de Prevalencia del VIH por Género y Grupo de Riesgo en Tijuana, México: 2006
墨西哥提华纳 Género y Grupo de Riesgo 的 VIH 流行病估计:2006 年
  • DOI:
  • 发表时间:
    2009
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Esmeralda Iñiguez;Kimberly C. Brouwer;Robert S. Hogg;Thomas L. Patterson;Remedios Lozada;Carlos Magis;John P. Elder;Rolando M. Viani;Steffanie A. Strathdee
  • 通讯作者:
    Steffanie A. Strathdee
Avoidant coping predicts psychological disturbance in the elderly.
回避应对预示着老年人的心理障碍。
  • DOI:
    10.1097/00005053-199017880-00010
  • 发表时间:
    1990
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Lawrence W. Smith;Thomas L. Patterson;Igor Grant
  • 通讯作者:
    Igor Grant
Analysis of the moderating effect of self-efficacy domains in different points of the dementia caregiving process
痴呆护理过程不同阶段自我效能域的调节作用分析
  • DOI:
  • 发表时间:
    2011
  • 期刊:
  • 影响因子:
    3.4
  • 作者:
    R. Romero;A. Losada;B. Mausbach;M. Márquez;Thomas L. Patterson;Javier López
  • 通讯作者:
    Javier López
Safe Injection Self-Efficacy is associated with HCV and HIV seropositivity among people who inject drugs in the San Diego-Tijuana border region
圣地亚哥-蒂华纳边境地区注射毒品者的安全注射自我效能感与 HCV 和 HIV 血清阳性有关
  • DOI:
    10.1101/2024.05.21.24307696
  • 发表时间:
    2024
  • 期刊:
  • 影响因子:
    0
  • 作者:
    K. Bailey;D. Abramovitz;G. Rangel;A. Harvey;C. Vera;Thomas L. Patterson;Jaime Arredondo Sánchez;Peter J Davidson;R. Garfein;L. R. Smith;Eileen V Pitpitan;Shira M Goldenberg;Steffanie A. Strathdee
  • 通讯作者:
    Steffanie A. Strathdee

Thomas L. Patterson的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Thomas L. Patterson', 18)}}的其他基金

Texting intervention to sustain HIV prevention in women in high-drug-use contexts
短信干预以维持高吸毒环境中女性的艾滋病毒预防
  • 批准号:
    8990602
  • 财政年份:
    2015
  • 资助金额:
    $ 9.69万
  • 项目类别:
Texting intervention to sustain HIV prevention in women in high-drug-use contexts
短信干预以维持高吸毒环境中女性的艾滋病毒预防
  • 批准号:
    9461499
  • 财政年份:
    2015
  • 资助金额:
    $ 9.69万
  • 项目类别:
HIV case finding and genetic transmission networks among MSM in Tijuana, Mexico
墨西哥蒂华纳 MSM 中的艾滋病毒病例发现和遗传传播网络
  • 批准号:
    8882384
  • 财政年份:
    2014
  • 资助金额:
    $ 9.69万
  • 项目类别:
HIV case finding and genetic transmission networks among MSM in Tijuana, Mexico
墨西哥蒂华纳 MSM 中的艾滋病毒病例发现和遗传传播网络
  • 批准号:
    8986571
  • 财政年份:
    2014
  • 资助金额:
    $ 9.69万
  • 项目类别:
Safer sex intervention for male clients of female sex workers in Tijuana, Mexico
对墨西哥蒂华纳女性性工作者的男性客户进行安全性行为干预
  • 批准号:
    8634323
  • 财政年份:
    2013
  • 资助金额:
    $ 9.69万
  • 项目类别:
Safer sex intervention for male clients of female sex workers in Tijuana, Mexico
对墨西哥蒂华纳女性性工作者的男性客户进行安全性行为干预
  • 批准号:
    8609008
  • 财政年份:
    2010
  • 资助金额:
    $ 9.69万
  • 项目类别:
Safer sex intervention for male clients of female sex workers in Tijuana, Mexico
对墨西哥蒂华纳女性性工作者的男性客户进行安全性行为干预
  • 批准号:
    8433406
  • 财政年份:
    2010
  • 资助金额:
    $ 9.69万
  • 项目类别:
Safer sex intervention for male clients of female sex workers in Tijuana, Mexico
对墨西哥蒂华纳女性性工作者的男性客户进行安全性行为干预
  • 批准号:
    8039154
  • 财政年份:
    2010
  • 资助金额:
    $ 9.69万
  • 项目类别:
Safer sex intervention for male clients of female sex workers in Tijuana, Mexico
对墨西哥蒂华纳女性性工作者的男性顾客进行安全性行为干预
  • 批准号:
    8232147
  • 财政年份:
    2010
  • 资助金额:
    $ 9.69万
  • 项目类别:
Prevenitng HIV/STIs in Central Indian High Risk Women: A Pilot Intervention
印度中部高危妇女预防艾滋病毒/性传播感染:试点干预措施
  • 批准号:
    7935271
  • 财政年份:
    2009
  • 资助金额:
    $ 9.69万
  • 项目类别:

相似海外基金

Pharmacy-led Transitions of Care Intervention to Address System-Level Barriers and Improve Medication Adherence in Socioeconomically Disadvantaged Populations
药房主导的护理干预转型,以解决系统层面的障碍并提高社会经济弱势群体的药物依从性
  • 批准号:
    10594350
  • 财政年份:
    2023
  • 资助金额:
    $ 9.69万
  • 项目类别:
Evaluating Centralizing Interventions to Address Low Adherence to Lung Cancer Screening Follow-up in Decentralized Settings
评估集中干预措施,以解决分散环境中肺癌筛查随访依从性低的问题
  • 批准号:
    10738120
  • 财政年份:
    2023
  • 资助金额:
    $ 9.69万
  • 项目类别:
Suubi-Mhealth: A mobile health intervention to address depression and improve ART adherence among Youth living with HIV (YLHIV) in Uganda
Suubi-Mhealth:一种移动健康干预措施,旨在解决乌干达艾滋病毒感染者 (YLHIV) 青少年的抑郁症问题并提高抗逆转录病毒疗法的依从性
  • 批准号:
    10526768
  • 财政年份:
    2022
  • 资助金额:
    $ 9.69万
  • 项目类别:
Suubi-Mhealth: A mobile health intervention to address depression and improve ART adherence among Youth living with HIV (YLHIV) in Uganda
Suubi-Mhealth:一种移动健康干预措施,旨在解决乌干达艾滋病毒感染者 (YLHIV) 青少年的抑郁症问题并提高抗逆转录病毒疗法的依从性
  • 批准号:
    10701072
  • 财政年份:
    2022
  • 资助金额:
    $ 9.69万
  • 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
  • 批准号:
    10679092
  • 财政年份:
    2021
  • 资助金额:
    $ 9.69万
  • 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
  • 批准号:
    10432133
  • 财政年份:
    2021
  • 资助金额:
    $ 9.69万
  • 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
  • 批准号:
    10327065
  • 财政年份:
    2021
  • 资助金额:
    $ 9.69万
  • 项目类别:
Leveraging Technology to Address Access and Adherence to Conventional Hospital-Based Pulmonary Rehabilitation in Veterans with COPD
利用技术解决慢性阻塞性肺病退伍军人接受和坚持传统医院肺康复的问题
  • 批准号:
    10377366
  • 财政年份:
    2019
  • 资助金额:
    $ 9.69万
  • 项目类别:
Leveraging Technology to Address Access and Adherence to Conventional Hospital-Based Pulmonary Rehabilitation in Veterans with COPD
利用技术解决慢性阻塞性肺病退伍军人接受和坚持传统医院肺康复的问题
  • 批准号:
    10574496
  • 财政年份:
    2019
  • 资助金额:
    $ 9.69万
  • 项目类别:
Targeted interventions to address the multi-level effects of gender-based violence on PrEP uptake and adherence among adolescent girls and young women in Kenya
有针对性的干预措施,以解决性别暴力对肯尼亚少女和年轻妇女接受和坚持 PrEP 的多层面影响
  • 批准号:
    9403567
  • 财政年份:
    2017
  • 资助金额:
    $ 9.69万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了