CORE B: HEALTH CARE AND POPULATION SCIENCE CORE
核心 B:医疗保健和人口科学核心
基本信息
- 批准号:9221321
- 负责人:
- 金额:$ 41.91万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2008
- 资助国家:美国
- 起止时间:2008-04-01 至 2019-01-31
- 项目状态:已结题
- 来源:
- 关键词:AdultArchivesAreaAttentionBehaviorBehavior TherapyBehavioralBiometryBody Weight decreasedCaringClinicClinicalClinical TrialsCollaborationsCommunitiesComplications of Diabetes MellitusCreativenessData QualityDatabasesDevelopmentDiabetes MellitusDiabetes preventionDiscipline of NursingDisease ManagementElderlyEpidemicEpidemiologyEvidence Based MedicineFosteringFundingGuidelinesHealthHealth Care ResearchHealth PolicyHealth systemHealthcareHeart DiseasesHumanInterventionInvestigationKnowledgeLaboratoriesLaboratory ResearchLinkMalignant NeoplasmsMarketingMarylandMeta-AnalysisMolecularNational Institute of Diabetes and Digestive and Kidney DiseasesNon-Insulin-Dependent Diabetes MellitusNursesOutcomes ResearchPaperPatient CarePatientsPharmaceutical PreparationsPharmacotherapyPhysiologicalPopulationPopulation ResearchPopulation SciencesPsychometricsPublic HealthPublicationsResearchResearch PersonnelResearch Project GrantsResearch SupportResourcesRisk FactorsRoleSafetyScienceScientistServicesTalentsTraining ProgramsTranslational ResearchUniversitiesbariatric surgerybasebench to bedsidebiomarker discoverycancer riskclinical decision-makingclinical practicecollaborative environmentcombatcomparativecomparative effectivenessdesigneffectiveness researchexperiencehealth disparityinterestmedical schoolsnovelnutrition related geneticspatient safetypersonalized medicinepopulation healthsevere mental illnesssymposiumsystematic reviewtreatment strategytrial designweb site
项目摘要
The NIDDK framework for translational research is expansive, ranging from bench to bedside all the way up
to community-based interventions. But this extensive framework leaves some important gaps: (1) It
sometimes disconnects laboratory from population research, impeding discovery of novel risk factors for
diabetes and novel complications of diabetes or diabetes treatment; (2) It sometimes assumes that large
trials have made treatment and prevention of diabetes matters of 'settled science', when in fact there are
lingering controversies; (3) It generally ignores patient safety as a subject of investigation, despite persistent
concerns about safety across a wide range of diabetes drugs and diabetes treatment strategies. (4) It
sometimes ignores the underiying clinical complexity of patients with diabetes, especially those who are
older or who have coexisting heart disease or cancer.
At the Hopkins-UMD DRC, we have a track record of supporting research that fills these gaps, often with
high-impact publications. We propose to construct a Healthcare & Population Science (HPS) Core that
support research to fill these gaps and thereby serve a unique role nationally among the DRCs and CDTRs:
The HPS Core will have 4 Sub-Cores: (1) Clinical, Molecular, and Pharmaco Epidemiology (Yeh, Segal)
(2) Clinical Trials (Brancati, Davis); 3) Behavior & Psychometrics Sub-Core (Hill-Briggs); (4) Biostatistics
Sub-Core (Wang). Themes of special interest will include: Health Disparities; Evidence-Based Medicine
(including Systematic reviews and Meta-analysis); Novel Risk Factors and Complications; Healthcare
interventions (including Population Health and Disease management; Bariatric Surgery; Personalized
Medicine; Tailored behavioral interventions; and Drug Safety.
NIDDK转化研究的框架是广泛的,从长凳到床头一直到床头
进行基于社区的干预措施。但是这个广泛的框架留下了一些重要的空白:(1)
有时将实验室与人口研究断开,阻碍了发现新的风险因素
糖尿病或糖尿病治疗的新型并发症; (2)有时假设很大
试验使“定居科学”的糖尿病事项进行了治疗和预防,而实际上有
争议; (3)尽管持续存在
对各种糖尿病药物和糖尿病治疗策略的安全性的担忧。 (4)它
有时忽略糖尿病患者的临床复杂性不足,尤其是那些
年龄较大或患有心脏病或癌症共存。
在Hopkins-umd drc,我们有一个支持研究的记录,以填补这些空白,通常
高影响力出版物。我们建议建造一个医疗保健与人口科学(HPS)核心
支持研究以填补这些空白,从而在刚果民主共和国和CDTR中发挥独特的作用:
HPS核心将具有4个子核:(1)临床,分子和药物流行病学(YEH,SEGAL)
(2)临床试验(Brancati,Davis); 3)行为和心理计核(Hill-Briggs); (4)生物统计学
子核(王)。特别感兴趣的主题将包括:健康差异;循证医学
(包括系统评价和荟萃分析);新的风险因素和并发症;卫生保健
干预措施(包括人口健康和疾病管理;减肥手术;个性化
药品;量身定制的行为干预;和药物安全。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
FREDERICK L BRANCATI其他文献
FREDERICK L BRANCATI的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('FREDERICK L BRANCATI', 18)}}的其他基金
Mechanisms and Effectiveness of Weight Loss Methods on Diabetes and Sleep Apnea
减肥方法对糖尿病和睡眠呼吸暂停的机制和有效性
- 批准号:
8277284 - 财政年份:2010
- 资助金额:
$ 41.91万 - 项目类别:
Mechanisms and Effectiveness of Weight Loss Methods on Diabetes and Sleep Apnea
减肥方法对糖尿病和睡眠呼吸暂停的机制和有效性
- 批准号:
8118425 - 财政年份:2010
- 资助金额:
$ 41.91万 - 项目类别:
Mechanisms and Effectiveness of Weight Loss Methods on Diabetes and Sleep Apnea
减肥方法对糖尿病和睡眠呼吸暂停的机制和有效性
- 批准号:
7992750 - 财政年份:2010
- 资助金额:
$ 41.91万 - 项目类别:
CORE B: HEALTH CARE AND POPULATION SCIENCE CORE
核心 B:医疗保健和人口科学核心
- 批准号:
8443953 - 财政年份:2008
- 资助金额:
$ 41.91万 - 项目类别:
CORE B: HEALTH CARE AND POPULATION SCIENCE CORE
核心 B:医疗保健和人口科学核心
- 批准号:
8629728 - 财政年份:2008
- 资助金额:
$ 41.91万 - 项目类别:
ACTION FOR HEALTH IN DIABETES (LOOK AHEAD)\PAR }
糖尿病健康行动(展望未来)PAR }
- 批准号:
7204436 - 财政年份:2004
- 资助金额:
$ 41.91万 - 项目类别:
相似国自然基金
科学基金档案资料信息化管理探索与实践研究
- 批准号:
- 批准年份:2022
- 资助金额:10 万元
- 项目类别:
面向单套制的国家自然科学基金项目档案分级分类管理研究
- 批准号:J2224001
- 批准年份:2022
- 资助金额:30.00 万元
- 项目类别:专项项目
科学基金档案资料信息化管理探索与实践研究
- 批准号:52242312
- 批准年份:2022
- 资助金额:10.00 万元
- 项目类别:专项项目
零信任架构下的电子健康档案动态共享研究
- 批准号:72274077
- 批准年份:2022
- 资助金额:45 万元
- 项目类别:面上项目
胶州湾河口湿地盾纤亚纲纤毛虫的多样性研究与档案资料建立
- 批准号:
- 批准年份:2021
- 资助金额:30 万元
- 项目类别:青年科学基金项目
相似海外基金
The Chicago Longitudinal Study: A low-income minority cohort from Birth to adulthood
芝加哥纵向研究:从出生到成年的低收入少数族群
- 批准号:
10430420 - 财政年份:2022
- 资助金额:
$ 41.91万 - 项目类别:
Effect of Perinatal Exposure to Metals on Lung Function Trajectories and Mitochondrial DNA Heteroplasmy from Childhood to Adolescence
围产期金属暴露对儿童期至青春期肺功能轨迹和线粒体 DNA 异质性的影响
- 批准号:
10446235 - 财政年份:2022
- 资助金额:
$ 41.91万 - 项目类别:
Cancer Prevention-Interception Targeted Agent Discovery Program at Fox Chase Cancer Center
福克斯蔡斯癌症中心的癌症预防-拦截靶向药物发现计划
- 批准号:
10505611 - 财政年份:2022
- 资助金额:
$ 41.91万 - 项目类别:
DYNAMICS OF M. TUBERCULOSIS-SPECIFIC INNATE AND ADAPTIVE IMMUNITY DURING PREGNANCY AND POSTPARTUM IN WOMEN WITH HIV
HIV 感染女性妊娠期和产后结核分枝杆菌特异性先天性和适应性免疫的动态
- 批准号:
10674692 - 财政年份:2022
- 资助金额:
$ 41.91万 - 项目类别:
DYNAMICS OF M. TUBERCULOSIS-SPECIFIC INNATE AND ADAPTIVE IMMUNITY DURING PREGNANCY AND POSTPARTUM IN WOMEN WITH HIV
HIV 感染女性妊娠期和产后结核分枝杆菌特异性先天性和适应性免疫的动态
- 批准号:
10356601 - 财政年份:2022
- 资助金额:
$ 41.91万 - 项目类别: