Career Enhancement Program

项目摘要 UTSW肾癌计划的职业提升计划(CEP)和孢子提供种子 为早期研究人员提供资金，他们的研究在早期就解决了重要的翻译目标 肾癌的检测、预防和治疗。CEP由精力充沛的领导层管理，具有强大的 出版记录，正如他们的资历和教学奖项所表明的那样，坚定不移地致力于 教育/培训。CEP的目标是吸引具有新奇想法和/或有才华的年轻调查人员 转化性肾癌研究中的实验方法。应聘者包括应用型和基础型 科学家、临床医生和内科科学家在肾癌领域工作，或者想要 将他们的专业知识和技能用于解决领域内的问题。 那些(I)为肾癌研究带来创新方法的人；(Ii)对克服 现有障碍；(3)有强大的项目，有可能最终获得外部资金支持或 成为完整的孢子项目。CEP提案将通过行政核心征求意见；它们将 由CEP领导层对资格、适宜性和相关性进行预先筛选；由两名内部人员和一名人员审查 外部专家；并由孢子执行委员会批准提供资金。孢子赠款提供了 每年50,000美元，再加上该机构提供的50,000美元，每年提供100,000美元，用于资助两到 每年三个CEP项目。CEP获奖者将被允许方便地使用所有孢子核心设施和 将是孢子会议不可分割的一部分，他们将在那里展示他们的工作。除了资金和 获得核心，CEP计划通过提供指导和职业发展来支持获奖者 指导旨在帮助年轻研究人员进行补助金和手稿准备、实验室管理等。 成功的衡量标准包括：邀请在国内和国际科学会议上发表演讲；成功 竞争国家卫生研究院/国防部/基金会的独立资助；发表原创研究报告；以及， 通过学术级别的提升，机构对独立性和生产力的认可。这个 UTSW肾癌孢子CEP的具体目标如下：1)作为一种招募和 支持初级教员的研究项目，重点是转化性肾癌研究。2)吸引 在其他器官部位有癌症研究经验的经验丰富的调查人员，他们希望将自己的专业知识集中在 转译肾癌研究。3)吸纳妇女和少数族裔进入CEP。4)培养科学的 CEP获奖者和职业发展，并协助将成功的CEP项目过渡到 竞争性申请同行评审的资金。丰富多样的研究兴趣/专业知识渠道 与UTSW肾癌相关的CEP动态扩展了CEP的广度和深度 孢子/肾癌计划的研究，如十个广泛包含的LOI的接收，以及 四项提案展示了出来。

Project Summary The Career Enhancement Program (CEP) of the UTSW Kidney Cancer Program and SPORE provides seed funding for early-stage investigators whose research addresses important translational objectives in early detection, prevention, and treatment of kidney cancer. The CEP is run by an energetic leadership with a strong publication record, and as illustrated by their credentials and teaching awards, an unwavering commitment to education/training. The goal of the CEP is to attract talented young investigators with novel ideas and/or experimental approaches in translational kidney cancer research. Candidates include applied and basic scientists, clinicians, and physician-scientists who are either working in the field of kidney cancer, or want to turn their expertise and skills toward tackling problems within the field. Particularly attractive candidates are those who (i) bring innovative approaches to kidney cancer research; (ii) have novel ideas for overcoming existing barriers; (iii) have strong projects with the potential to eventually garner outside funding support or become full SPORE projects. CEP proposals will be solicited via the Administrative Core; they will be prescreened for eligibility, suitability, and relevance by the CEP leadership; reviewed by two internal and one external expert; and approved for funding by the SPORE Executive Committee. The SPORE grant provides $50,000 annually, which is matched by $50,000 from the institution, providing $100,000 per year to fund two to three CEP projects annually. CEP awardees will be granted expedient access to all SPORE Core facilities and will be an integral part of SPORE meetings, where they will present their work. In addition to funding and access to Cores, the CEP program supports awardees by offering mentoring and career development guidance designed to assist young investigators in grant and manuscript preparation, lab management, etc. Metrics of success include: invitations to present at national and international scientific meetings; successful competition for independent NIH/DOD/Foundation grant support; publication of original research studies; and, institutional recognition of independence and productivity by promotion through the academic ranks. The specific aims of the UTSW Kidney Cancer SPORE CEP are as follows: 1) Serve as a mechanism to recruit and support junior faculty with research projects focusing on translational kidney cancer research. 2) Attract seasoned investigators with experience in cancer at other organ sites who want to focus their expertise on translational kidney cancer research. 3) Recruit women and minorities into the CEP. 4) Nurture the scientific and career development of the CEP awardees, and assist with transitioning successful CEP projects into competitive applications for peer-reviewed funding. A rich and diverse pipeline of research interests/expertise pertinent to kidney cancers at UTSW populates a dynamic CEP expanding the breadth and depth of the SPORE/Kidney Cancer Program research as illustrated by the reception of ten wide-encompassing LOIs, and the four proposals showcased.