Accompanying HIV-positive adolescents through the transition into adult care: a feasibility study

陪伴艾滋病毒阳性青少年过渡到成人护理：可行性研究

• 批准号: 9886206
• 负责人: Molly Forrest Franke
• 金额: $ 19.42万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-05 至 2022-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9886206
• 关键词: Acquired Immunodeficiency Syndrome; Address; Adherence; Adolescence; Adolescent; Adult; Behavioral; CD4 Lymphocyte Count; Caring; Cessation of life; Child; Childhood; Clinical; Communities; Community Health Aides; Complex; Consent; Coping Skills; Data; Data Collection; Development; Disclosure; Disease Management; Emotional; Ensure; Evaluation; Face; Feasibility Studies; Future; HIV; HIV Seropositivity; Health; Health Services; Health Status; Intervention; Intervention Studies; Intervention Trial; Legal; Logistics; Measures; Medical; Mental Health; Neurocognitive; Newly Diagnosed; Outcome; Outcome Assessment; Patient Care; Patients; Performance; Perinatal; Peru; Pharmaceutical Preparations; Pilot Projects; Population; Pregnancy; Procedures; Prospective Studies; Provider; Reporting; Research Personnel; Sample Size; Schools; Social support; Time; Training; Viral Load result; antiretroviral therapy; barrier to care; base; behavioral outcome; cohort; design; follow-up; improved; medication compliance; multidisciplinary; programs; psychosocial; recruit; sexual debut; social exclusion; social stigma; support network; supportive environment; therapy design; tool; transgender women; transmission process; young men who have sex with men

PROJECT SUMMARY/ABSTRACT The transition to adult HIV care is often accompanied by reduced medication adherence, retention, HIV viral load suppression and CD4 cell counts; however, little is known about which interventions might be most effective in supporting adolescents undergoing this care transition. We will conduct a feasibility study for a community-based accompaniment intervention, delivered by community health workers, that is designed to improve health outcomes among adolescents transitioning to adult care in urban Peru. We will (1) conduct an intervention pilot to determine the feasibility of an accompaniment intervention designed to improved retention with viral load suppression (i.e., “successful transition”) among a diverse cohort of adolescents living with HIV; (2) pilot study procedures relevant to a future intervention trial; and (3) conduct a retrospective chart review to collect data to inform recruitment and sample size calculations for a future intervention trial.

项目总结/摘要 向成人艾滋病毒护理的过渡往往伴随着药物依从性、保留、艾滋病毒载量的降低 抑制和CD 4细胞计数;然而，对于哪些干预措施可能最有效， 支持正在经历这种护理过渡的青少年。我们会进行可行性研究， 由社区卫生工作者提供的旨在改善健康的伴随干预 秘鲁城市中向成人护理过渡的青少年的结果。我们将（1）进行干预试点 确定旨在改善病毒载量保留的伴随干预的可行性 抑制（即，（2）试点研究 与未来干预试验相关的程序;以及（3）进行回顾性病历审查，以收集数据， 为未来的干预试验提供信息招募和样本量计算。

项目成果

[Impact of SARS-CoV-2 pandemic on adolescents living with HIV in Lima, Peru].

[SARS-COV-2大流行对秘鲁利马艾滋病毒的青少年的影响]。

• DOI: 10.17843/rpmesp.2021.381.6296
• 发表时间: 2021-01
• 期刊: Revista peruana de medicina experimental y salud publica
• 作者: Errea RA;Wong M;Senador L;Ramos A;Ramos K;Galea JT;Lecca L;Sánchez H;Benites C;Franke MF
• 通讯作者: Franke MF

A non-specialist depression care pathway for adolescents living with HIV and transitioning into adult care in Peru: a nested, proof of concept pilot study.

• DOI: 10.1017/gmh.2021.16
• 发表时间: 2021
• 期刊: Global mental health (Cambridge, England)
• 作者: Galea JT;Contreras C;Wong M;Ramos K;Vargas V;Sánchez H;Errea RA;Lecca L;Franke MF
• 通讯作者: Franke MF

Patient and provider perceptions of a community-based accompaniment intervention for adolescents transitioning to adult HIV care in urban Peru: a qualitative analysis.

• DOI: 10.1002/jia2.26019
• 发表时间: 2022-10
• 期刊: JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
• 影响因子: 6
• 作者: Galea, Jerome T.;Wong, Milagros;Ninesling, Brennan;Ramos, Alicia;Senador, Liz;Sanchez, Hugo;Kolevic, Lenka;Matos, Eduardo;Sanchez, Eduardo;Errea, Renato A.;Lindeborg, Andrew;Benites, Carlos;Lecca, Leonid;Shin, Sonya;Franke, Molly F.
• 通讯作者: Franke, Molly F.

Community-based accompaniment for adolescents transitioning to adult HIV care in urban Peru: a pilot study.

• DOI: 10.1007/s10461-022-03725-2
• 发表时间: 2022-12
• 期刊: AIDS and behavior
• 影响因子: 4.4
• 作者: Vargas V;Wong M;Rodriguez CA;Sanchez H;Galea J;Ramos A;Senador L;Kolevic L;Matos E;Sanchez E;Errea RA;Ramos K;Beckhorn C;Lindeborg A;Benites C;Lecca L;Shin S;Franke MF
• 通讯作者: Franke MF