2019 Atherosclerosis Gordon Research Conference and Gordon Research Seminar

项目总结 2019年戈登动脉粥样硬化研究会议的总主题是`来自分子和 动脉粥样硬化治疗方法的细胞洞察力。这次会议的目标是提供一个 全面概述该领域的最新前沿研究和最新发展，特别是 那些利用最新的方法和最有希望的方法来促进预防和 心血管疾病的治疗。这次会议的一个独特和主要的方面是期望 演讲者将展示来自他们实验室的未发表的新研究，这将允许进行大讨论 在这次会议的过去40年里，我们了解到动脉粥样硬化是一种 由炎症、自身免疫、脂质和血管生物学成分组成的复杂疾病。在这2019年 GRC，我们想以全新的视角看待这些疾病的每一个组成部分。我们计划讨论并提出问题 关于动脉粥样硬化性疾病进展的当前教条，了解新分子和新细胞 机械作用于动脉粥样硬化发展的途径，探讨如何利用新高 用空间方法研究动脉粥样硬化斑块的细胞和分子成分，并鉴定 并讨论新的临床目标-所有这些目标都是为了治疗并最终预防动脉粥样硬化。会议 在血管生物学、血脂异常、先天性和获得性免疫、非编码RNA以及新的治疗方法方面 都是有计划的。对于年轻的研究人员和实习生来说，有很多机会简要介绍他们的工作 谈话和海报会议。美丽的星期日河会议现场的大学氛围非常 放松，下午和晚上的非正式聚会，结束了多个讨论环节 “社区”餐饮和户外社交活动。会场为与会者提供了绝佳的机会 建立网络并建立新的合作关系。这次会议以非正式的方式将年轻人和 成熟的调查人员，为年轻的调查人员和受训人员提供一个与领导人互动的论坛 在一个积极、放松的论坛上。 在参与者中。

PROJECT SUMMARY The overall theme of the 2019 Gordon Research Conference on Atherosclerosis is `From Molecular and Cellular Insights to Therapeutic Approaches in Atherosclerosis'. The goal of this conference is to provide a comprehensive overview of the latest cutting-edge research and newest developments in the field, particularly those harnessing the newest methodologies and most promising approaches to promote the prevention and treatment of cardiovascular disease. A unique and major aspect of this conference is the expectation that speakers will present unpublished new research from their laboratories, which allows for great discussion Over the past four decades of this conference, we have learned that atherosclerosis is a complex disease consisting of inflammatory, autoimmune, lipid, and vascular biology components. In this 2019 GRC, we want to take a fresh new look at each of these disease components. We plan to discuss and question the current dogmas about atherosclerotic disease progression, learn about new molecules and new cellular pathways that mechanistically play a role in atherosclerosis development, discuss how to utilize new high dimensional methods to study cellular and molecular components of the atherosclerotic plaque, and identify and discuss new clinical targets – all with the goals to treat, and ultimately prevent, atherosclerosis. Sessions on vascular biology, dyslipidemia, innate and adaptive immunity, noncoding RNAs, and novel therapies have been planned. There are many opportunities for young investigators and trainees to present their work in short talks and in poster sessions. The collegial atmosphere of the beautiful Sunday River conference site is very relaxed, with informal gatherings in the afternoons and evenings, multiple discussion sessions over `community' meals, and outdoor social activities. The venue allows wonderful opportunities for attendees to network and forge new collaborations. The conference brings together in an informal manner young and established investigators, providing a forum in which young investigators and trainees can interact with leaders in the field in a positive, relaxing forum. among participants.