Career Enhancement Program

项目总结(职业提升计划) 职业提升计划(CEP)的目标是为学术研究提供培训和指导 希望奉献其职业生涯的医生-科学家、临床医生-研究人员和基于实验室的科学家 并致力于白血病的研究翻译研究。为了实现这一目标，CEP将开展以下工作 具体目标： 1.招募、培训和指导医生、科学家和高级博士后研究员 优秀的白血病研究人员专注于白血病的翻译研究。 2.向获奖者传授癌症和白血病生物学的所有基本原理，包括分子、细胞 和系统生物学、药物开发、药代动力学和药效学研究，以及基础 生物统计学和生物信息学原理。 3.为白血病翻译和早期临床特定领域的获奖者提供坚实的基础 研究。 这些目标将通过强有力的指导来实现，获奖者将在 白血病的临床、基础和转化性研究原理。具体的教育领域将包括 科学和临床方法，生物医学伦理学，统计设计和分析，生物信息学，生物学， 生物化学、遗传学、流行病学和其他与个别项目相关的领域。导师制将包括 实验室调查人员、临床翻译调查人员、生物统计学家、生物信息学家和 流行病学家。来自白血病孢子和MD其他1500名教职员工的导师 安德森癌症中心、生物医学研究生院、福克斯·蔡斯癌症中心和来自 位于休斯敦的德克萨斯大学将提供发展强大、高产所需的专业知识 翻译研究技能。 自2003年成立以来，CEP已资助了54个奖项，授予36名获奖者，其中包括14名女性和14名 少数族裔，他们获得了设计和实施基于临床的翻译的技能和专业知识 白血病研究，包括将以实验室为基础的研究纳入临床试验，反过来， 将关键的临床观察转化为有意义的实验室研究。大多数人都有 在白血病或癌症研究方面继续独立的学术生涯。因此，这个项目做出了贡献 对事业发展有才华的青年白血病科研人员加快发展是有效的 针对白血病的新治疗策略。

PROJECT SUMMARY (Career Enhancement Program) The goal of the Career Enhancement Program (CEP) is to provide training and guidance for academic physician-scientists, clinician-investigators, and laboratory-based scientists who wish to dedicate their career and research efforts to leukemia translational research. To achieve this goal, the CEP will pursue the following specific aims: 1. Recruit, train, and mentor physicians, scientists, and senior postdoctoral fellows to become excellent leukemia investigators focused on leukemia translational research. 2. Educate awardees in all the basic principles of cancer and leukemia biology, including molecular, cellular and systems biology, drug development, pharmacokinetic and pharmacodynamics studies, and basic principles of biostatistics and bioinformatics. 3. Provide a firm foundation for awardees in the specific area of leukemia translational and early clinical research. These objectives will be achieved through strong mentorship in which awardees will be instructed in the principles of clinical, basic, and translational leukemia research. Specific areas of education will include scientific and clinical methods, biomedical ethics, statistical design and analysis, bioinformatics, biology, biochemistry, genetics, epidemiology, and other areas relevant to individual projects. Mentorship will include laboratory-based investigators, clinical-translational investigators, biostatisticians, bioinformaticians and epidemiologists. Mentors from within the Leukemia SPORE and the other 1,500 faculty members at the MD Anderson Cancer Center, Graduate School of Biomedical Sciences, Fox Chase Cancer Center and from the University of Texas in Houston, will provide the expertise required for the development of strong, productive translational research skills. Since its inception in 2003, the CEP has funded 54 awards given to 36 recipients, including 14 women and 14 minorities, who have gained skills and expertise in designing and conducting clinical translational-based studies in leukemia, including incorporating laboratory-based studies in clinical trials and, conversely, transforming critical clinical observations into meaningful laboratory investigations. The majority have continued independent academic careers in leukemia or cancer research. Thus, this program has contributed to the career development of talented young leukemia investigators to hasten the development of effective new therapeutic strategies against leukemia.