AIM to Improve Asthma: Airflow Improvements during Meal-prep
AIM to Improve Asthma: Airflow Improvements during Meal-prep
批准号:
9896653
负责人:
John R Balmes
金额:
$30.55万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-03-18 至 2022-12-31
关键词:
AdvocacyAffectAgeAir MovementsAir PollutantsAsthmaAwarenessBuilding CodesCaliforniaChemicalsChildChildhoodChildhood AsthmaChronic DiseaseCitiesCommunitiesControl GroupsDataData CollectionDeveloped CountriesEducationEducational MaterialsEducational process of instructingEnvironmental HealthEventExhalationFamilyGasesGoalsHealth PromotionHealth educationHome environmentHourHouseholdHousehold Air PollutionIndoor Air PollutionInterventionInterviewLeadLeadershipLow incomeLung diseasesManufacturer NameMeasurementMeasuresModelingNitric OxideNitrogen DioxideNoiseParticipantParticulate MatterPatternPhysiciansPrevalenceQuality of lifeQuestionnairesRandomizedRandomized Controlled TrialsRecommendationReportingResearchResearch DesignResearch MethodologyResearch Project GrantsResourcesRespiratory Signs and SymptomsRespiratory physiologyRoleSalinas ValleySample SizeSamplingSchoolsSourceSpirometrySymptomsTestingTrainingUnited StatesVisitYouthairway inflammationasthma exacerbationcommunity based participatory researchcookingcostdesignexhaustfine particlesfootimprovedindoor particulate matterindoor pollutantmemberpollutantpublic health prioritiesrandomized trialrecruitsensorskillsventilationvolatile organic compound
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Asthma is one of the most prevalent chronic diseases of childhood. Because children spend many hours
indoors at home, interventions to decrease asthma-exacerbating exposures in the home could have profound
impacts. In addition, many pollutants, such as fine particulate matter (PM2.5) and Nitrogen dioxide (NO2) have
higher levels indoors than outdoors, even in the developed world. Air pollutants may worsen asthma
symptoms through multiple mechanisms, including by directly increasing airways inflammation. One of the
primary sources of indoor pollutants in the United States is cooking with gas stoves, and cooking-related
pollutants have been shown to be related to increases in asthma symptoms. In a nationally representative
sample, children who live in homes where cooking ventilation is not used have higher rates of asthma and
other respiratory diseases. This study will be a pilot stepped-wedge randomized trial in homes with both a child
with asthma and a gas stove, assessing an intensive cooking ventilation intervention. The long-term goal is to
provide the scientific rationale for an easily implementable household air pollution intervention. The primary
aim of this project will be to assess the effect of the cooking ventilation intervention on household PM2.5 and
NO2 levels, and a secondary aim is to assess the effect of the cooking ventilation on short-term measures of
pediatric asthma control, as improvements could result either from changes in PM2.5 and NO2 or from changes
in other chemicals. As a youth participatory action research project, a third aim will be to develop scientific
leadership capacity in community youth. This will be the first trial to both replace stove hoods for improved
cooking ventilation in the homes of children with asthma and objectively measure both stove and hood fan use.
Moreover, the stepped wedge design will allow for analysis in two ways: first as a randomized controlled trial
(to minimize confounding) and secondly as a before-after trial (to maximize sample size). All homes will
receive measurement of air flow through the range hood, and an intervention with two parts: (1) replacement of
the range hood if air flow is less than the California building code level of 100 cubic feet per minute (cfm) or
intolerably noisy and (2) intensive education regarding the use of the range hood during all cooking events and
cleaning of the grease screen. A manufacturer (Broan), which has no role in the design of the study, plans to
provide replacement hoods if the airflow is inadequate. Stove and Range hood sensors will also be installed in
participant homes for the entire 3-week data collection period, with study visits at initiation and every week
thereafter, for a total of four visits spanning three weeks of data collection. Those randomized to group 1 (30
homes) will receive the intervention after one week of baseline data collection and group 2 (30 homes) will
receive it after two weeks. Measured variables will include stove use, range hood use, PM2.5 and NO2 in the
household, and multiple measures of asthma control in the children (spirometry, Fractional exhaled Nitric
Oxide, asthma control questionnaire, ISAAC Asthma and Environmental Questionnaires).
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会议论文
OCCUPATIONAL SAFETY AND HEALTH EDUCATION AND RESEARCH CENTERS (T42)
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批准号:10044571
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项目类别:
-
资助金额:$179.97万
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财政年份:2020
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负责人:John R Balmes
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依托单位:
CHAPS Cohort Maintenance
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批准号:10302315
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项目类别:
-
资助金额:$38.9万
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财政年份:2020
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负责人:John R Balmes
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依托单位:
CHAPS Cohort Maintenance
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批准号:10524022
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项目类别:
-
资助金额:$37.51万
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财政年份:2020
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负责人:John R Balmes
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依托单位:
OCCUPATIONAL SAFETY AND HEALTH EDUCATION AND RESEARCH CENTERS (T42)
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批准号:10255488
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项目类别:
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资助金额:$167.71万
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财政年份:2020
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负责人:John R Balmes
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依托单位:
Cluster Randomized Controlled Trial of an Advanced Stove to Reduce Risk of COPD
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批准号:8887404
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项目类别:
-
资助金额:$11.99万
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财政年份:2014
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负责人:John R Balmes
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依托单位:
UC Berkeley/Stanford Children's Enviromental Health Center
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批准号:8702173
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项目类别:
-
资助金额:$78.94万
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财政年份:2013
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负责人:John R Balmes
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依托单位:
UC Berkeley/Stanford Children's Enviromental Health Center
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批准号:9325525
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项目类别:
-
资助金额:$79.39万
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财政年份:2013
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负责人:John R Balmes
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依托单位:
UC Berkeley/Stanford Children's Enviromental Health Center
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批准号:9070674
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项目类别:
-
资助金额:$80.35万
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财政年份:2013
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负责人:John R Balmes
-
依托单位:
UC Berkeley/Stanford Children's Enviromental Health Center
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批准号:8513476
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项目类别:
-
资助金额:$82.85万
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财政年份:2013
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负责人:John R Balmes
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依托单位:
UC Berkeley/Stanford Children's Enviromental Health Center
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批准号:8857451
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项目类别:
-
资助金额:$79.15万
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财政年份:2013
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负责人:John R Balmes
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依托单位:
Targeted Research Training Core
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批准号:7488284
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项目类别:
-
资助金额:$19.4万
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财政年份:2008
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负责人:John R Balmes
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依托单位:
Occupational Safety and Health Education and Research Centers
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批准号:7645597
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项目类别:
-
资助金额:$124.27万
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财政年份:2007
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负责人:John R Balmes
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依托单位:
Occupational Safety and Health Education and Research Centers
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批准号:7896178
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项目类别:
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资助金额:$12.19万
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财政年份:2007
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负责人:John R Balmes
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依托单位:
Occupational Safety and Health Education and Research Centers
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批准号:7288045
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项目类别:
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资助金额:$104.34万
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财政年份:2007
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负责人:John R Balmes
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依托单位:
Occupational Safety and Health Education and Research Centers
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批准号:7478025
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项目类别:
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资助金额:$100.94万
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财政年份:2007
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负责人:John R Balmes
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依托单位:
Occupational Safety and Health Education and Research Centers
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批准号:7661916
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项目类别:
-
资助金额:$3.93万
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财政年份:2007
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负责人:John R Balmes
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依托单位:
Occupational Safety and Health Education and Research Centers
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批准号:8717431
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项目类别:
-
资助金额:$114.74万
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财政年份:2005
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负责人:John R Balmes
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依托单位:
Occupational Safety and Health Education and Research Centers
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批准号:8308262
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项目类别:
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资助金额:$150.25万
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财政年份:2005
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负责人:John R Balmes
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依托单位:
Berkeley Center for Environmental Public Health Tracking
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批准号:7124224
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项目类别:
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资助金额:$45.0万
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财政年份:2005
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负责人:John R Balmes
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依托单位:
Berkeley Center for Environmental Public Health Tracking
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批准号:7273636
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项目类别:
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资助金额:$45.0万
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财政年份:2005
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负责人:John R Balmes
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依托单位:
海外基金