Multimethod Cancer Outcomes Research Shared Resource

多方法癌症结果研究共享资源 项目总结/摘要 多方法癌症成果研究共享资源（癌症成果SR）是一个重要的资产， 案例综合癌症中心（案例CCC）成员的研究，说明了科学的广度 项目参与，并反映在使用此SR的调查人员数量上。仅去年一年， 7个案例CCC项目中有5个项目的研究者使用SR，其中88%是案例CCC成员。 癌症结局SR帮助研究人员解决癌症预防或治疗中复杂的多因素挑战。 控制，需要一个连接，多方法的方法。癌症成果SR将人们联系起来， 组织，和数据，以推动癌症研究的整个频谱：发现干预发展， 执行、传播和成果评价。癌症成果SR投资于开发深度 与社区组织的伙伴关系，大型数据库基础设施和方法学专业知识， 集成了定量和定性方法，以支持复杂系统建模和多层次 干预措施，以改善癌症的结果。癌症结局SR的具体目标是： 1.培养丰富的社区伙伴关系、数据基础设施和方法专业知识， 开展以癌症为重点的相关研究。 2.在理解癌症风险因素、合并症、癌症的社会决定因素方面进行基础癌症研究 健康、行为测量和干预机会。 3.连接不同的方法和合作伙伴，以支持复杂的观察和干预研究 癌症控制问题。 在上次审查中，癌症结局SR被评为优秀至优秀。纵观当前 在2012-2016年资助周期内，癌症成果SR为104名注册用户提供了服务，其中29名（28%） 他们是案例CCC成员，代表了7个案例CCC项目中的5个。 癌症成果SR的目标是通过以下方式实现的： 超越个人项目的研究合作伙伴;提供行为和结果测量方面的专业知识; 定量与定性相结合;支持多层次干预设计;链接与分析 公共卫生和医疗保健系统数据库;支持仿真建模。癌症的结果 SR正在积极扩大其人口健康数据基础设施，以支持新的研究，并加快 为研究者提供的基于邻里和社区的背景数据与队列研究的整合 开展流域相关研究。

MULTIMETHOD CANCER OUTCOMES RESEARCH SHARED RESOURCE PROJECT SUMMARY/ABSTRACT The Multimethod Cancer Outcomes Research Shared Resource (Cancer Outcomes SR) is an essential asset to Case Comprehensive Cancer Center (Case CCC) members' research, illustrated by the breadth of scientific program involvement and reflected in the number of investigators who use this SR. Last year alone, 25 investigators, 88% of whom were Case CCC members, from 5 out of the 7 Case CCC programs used the SR. The Cancer Outcomes SR helps researchers address complex, multifactorial challenges in cancer prevention or control that require a connected, multimethod approach. The Cancer Outcomes SR connects people, organizations, and data to advance cancer research across the spectrum: discovery to intervention development, implementation, dissemination, and outcome evaluation. The Cancer Outcomes SR invests in developing deep partnerships with community organizations, large database infrastructure, and methodological expertise that integrates quantitative and qualitative methods to support complex systems modeling and multilevel interventions to improve cancer outcomes. The Specific Aims of the Cancer Outcomes SR are to: 1. Cultivate rich community partnerships, data infrastructures, and methodological expertise to enable the conduct of relevant cancer-focused research. 2. Ground cancer research in understanding of cancer risk factors, co-morbidities, social determinants of health, behavioral measurement, and intervention opportunities. 3. Connect diverse methods and partners to support observational and intervention research on complex cancer control problems. At last review, the Cancer Outcomes SR was rated Outstanding to Excellent merit. Throughout the current funding cycle (2012-2016), the Cancer Outcomes SR provided services to 104 registered users, 29 (28%) of whom are Case CCC members, representing 5 out of the 7 Case CCC programs. The aims of the Cancer Outcomes SR are accomplished by: Developing collaborations with diverse community research partners that transcend individual projects; Providing expertise in behavioral & outcome measurement; Integrating quantitative and qualitative methods; Supporting multilevel intervention design; Linking and analyzing public health and health care system databases; and Supporting simulation modeling. The Cancer Outcomes SR is actively expanding its population health data infrastructure to support novel research and to accelerate the integration of neighborhood- and community-based contextual data for investigators with cohort studies conducting catchment area relevant research.