Central Nervous System Dysfunction Scientific Working Group

中枢神经系统功能障碍工作组将促进跨学科合作，重点是更好地了解艾滋病毒感染者中枢神经系统功能障碍的方法。我们的目标是：1.通过向对艾滋病毒研究有新兴趣的年轻临床医生和非临床医生研究人员提供资源和指导，促进我们多样化团队的发展。我们尤其有能力促进那些对分层和临床预测建模的计算方法、用于精确成像的生物标记物目标的验证、新生物标记物的识别(利用信息学)以及开发新的精确技术(如分子遗传成像)感兴趣的人的成功。·参与CNS功能障碍研究的初级调查人员数量SWG·CFAR内部和跨CFAR建立的合作数量，包括艾滋病毒研究的新手或艾滋病毒经验和CNS功能障碍研究的新手·这些CNS功能障碍HIV研究的初级或新研究员提交的摘要/手稿数量·CFAR/P30试点或其他奖项授予这些CNS功能障碍艾滋病毒研究的初级或新研究员2.促进新方案的开发和成功，以生成新的数据(例如，临床、神经成像、生物成像)或使用现有的临床数据，如电子健康记录(EHR)、多领域神经心理和精神健康数据、生物医学特征、和神经成像，以确定患有中枢神经系统功能障碍和合并症的艾滋病毒患者的特征·#份提交的NIH或其他与神经艾滋病毒有关的赠款·#份提交的方案，其中包括艾滋病毒/艾滋病研究领域以外的新专业知识·#份神经艾滋病毒的新手稿·#份CFAR学者奖

The CNS dysfunction SWG will facilitate interdisciplinary collaborations focusing on approaches to better understanding CNS dysfunction among people with HIV. Our goals are: 1. Promote the growth of our diverse team through provision of resources and mentorship to young clinician and non-clinician investigators who have new interest in HIV research. We are particularly well-positioned to foster the success of those with interests in computational approaches to stratification and clinical prediction modeling, validation of biomarker targets for precision imaging, identification of new biomarkers (with informatics), and development of new precision techniques such as molecular-genetic imaging. • Number of junior investigators involved with CNS dysfunction SWG • Number of collaborations established within & across CFAR, including individuals new to HIV research or HIV-experienced & new to CNS dysfunction research • Number of abstracts/manuscripts submitted by these junior or new investigators to CNS dysfunction HIV research • Number of CFAR/P30 pilot or other awards to these junior or new investigators to CNS dysfunction HIV research 2. Facilitate the development and success of new protocols that generate new data (e.g., clinical, neuroimaging, biospecimens) or use existing clinical datasets such as the electronic health record (EHR), multi-domain neuropsychological and mental health data, biospecimen characteristics, and neuroimaging toward characterizing people with HIV with CNS dysfunction and comorbidities • # of submitted NIH or other grants related to NeuroHIV • # of submitted protocols that include novel expertise from outside the field of HIV/AIDS research • # new manuscripts in NeuroHIV • # CFAR scholar awards