Multiplexed wireless battery-free sensors for pediatric intensive care units (PICU).

适用于儿科重症监护病房 (PICU) 的多路无线无电池传感器。

• 批准号: 9908207
• 负责人: Jeffrey Model
• 金额: $ 22.48万
• 依托单位: WEARIFI, INC.
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-08 至 2023-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9908207
• 关键词: Address; Ambulatory Care; Anxiety; Beds; Blood; Blood Pressure; Blood flow; Businesses; Caliber; Cardiac Catheterization Procedures; Cardiac Output; Cardiovascular system; Caregivers; Caring; Cellular Phone; Chicago; Childhood; Clinical; Common Ventricle; Complication; Coupling; Custom; Data; Decision Making; Devices; Encapsulated; Engineering; Equipment; Family; Goals; Gold; Head; Heart; Heart Rate; Hospitals; Hour; Laboratories; Lead; Length of Stay; Logistics; Maps; Mattresses; Measurement; Measures; Methods; Mission; Monitor; Morbidity - disease rate; Morphologic artifacts; Motion; Movement; National Institute of Child Health and Human Development; Neonatal; Operative Surgical Procedures; Output; Oxygen; Palliative Care; Patient Monitoring; Patients; Pediatric Hospitals; Pediatric Intensive Care Units; Pediatric Surgical Procedures; Perfusion; Perinatal; Peripheral; Peripheral Resistance; Persons; Physiologic Monitoring; Physiologic pulse; Physiological; Pilot Projects; Psychological Impact; Pulse Oximetry; Reader; Reading; Reporting; Resistance; Risk; Statistical Data Interpretation; System; Tablets; Techniques; Technology; Temperature; Testing; Thinness; Thoracic Surgical Procedures; Time; Tissues; Translations; Tube; United States National Institutes of Health; Universities; Validation; Vascular resistance; Venous; Wireless Technology; Work; acute care; base; cardiac intensive care unit; care providers; clinical care; cost; design; fundamental research; hemodynamics; improved; indexing; innovation; inpatient service; interest; medical schools; neonate; oxygen transport; patient mobility; patient monitoring device; pilot trial; programs; reconstruction; sensor; standard of care; symposium; tool; validation studies

Project Summary In the pediatric intensive care unit (PICU) monitoring of hemodynamics and oxygen transport provide critical information needed by care providers for decision making. Patients end up with so many wires, tubes and umbilicals that access to the patient and movement become limited. Furthermore, many of these monitoring techniques are invasive, and for the frailest patients in the PICU, often result in suffering or even morbidity. There is an urgent need for reducing invasive monitoring and the number of wires that get attached to PICU patients, while still providing the critical physiological data that care providers rely on. Wearifi, Inc. is working to develop a platform for wireless battery-free patient monitoring. In this proposal the platform will be applied to the PICU setting to reduce the number of wires that are attached to patients and to investigate if the system can provide a surrogate or indicator for parameters that are traditionally only available from invasive monitoring techniques. The specific aims of this work include 1) hardening of the platform for clinical use and compatibility with standard patient monitors, 2) validation pilot study in the pediatric cardiac intensive care unit (PCICU), and 3) an attempt to correlate data from the wireless sensor platform to additional markers of interest such as systematic vascular resistance (SVR). This project fits the mission of the NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). In particular it is well aligned with the objectives of the RFA-HD-19-001 Safe and Effective Devices for Use In Neonatal, Perinatal and Pediatric Care Settings. We have assembled a highly qualified and competent team form the small business Wearifi, Inc. and clinical experts from Northwestern University’s Ann & Robert H Lurie Hospital and Feinberg School of Medicine to develop and test innovative patient monitoring devices for use in the pediatric intensive care unit.

项目摘要 在儿科重症监护病房(PICU)监测血流动力学和氧气转运 为护理人员提供决策所需的关键信息。患者最终会患上 太多的电线、管子和脐带，以至于接触病人和移动变得有限。 此外，这些监测技术中的许多都是侵入性的，对于 在PICU，往往会导致痛苦甚至发病。迫切需要减少 侵入性监测和连接到PICU患者的电线数量，同时仍 提供护理人员所依赖的关键生理数据。Wearifi，Inc.正在努力 开发无线无电池患者监护平台。在本提案中，平台将 应用于PICU设置，以减少连接到患者和 调查系统是否可以为传统的参数提供代理或指示器 只有通过侵入性监测技术才能获得。这项工作的具体目标包括1) 加强临床使用的平台，并与标准患者监护仪兼容，2) 儿科心脏重症监护病房(PCICU)的验证性先导研究，以及3)尝试 将来自无线传感器平台的数据与其他感兴趣的标记相关联，例如 系统性血管阻力(SVR)。该项目符合美国国立卫生研究院尤尼斯·肯尼迪的使命 施莱弗国家儿童健康和人类发展研究所(NICHD)。尤其是它是 与RFA-HD-19-001安全有效设备的目标很好地保持一致 新生儿、围产期和儿科护理设置。我们已经组建了一支非常合格的 由来自西北大学的小企业Wearifi，Inc.和临床专家组成的称职团队 安罗伯特·H·鲁里医院和范伯格医学院将共同开发和测试 用于儿科重症监护病房的创新患者监护设备。