PrEP Up!: Understanding PrEP stigma to improve uptake among men who have sex with men

PrEP Up!:了解 PrEP 耻辱以提高男男性行为者的接受度

基本信息

  • 批准号:
    9914144
  • 负责人:
  • 金额:
    $ 16.94万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-04-15 至 2022-02-28
  • 项目状态:
    已结题

项目摘要

Project Summary/Abstract Men who have sex with men (MSM) are disproportionately affected by HIV in Guatemala. While national level adult HIV prevalence is less than 1.0%, the most recent prevalence estimate among MSM is 10.5%. This dramatic HIV disparity suggests that current prevention strategies are not sufficient. Pre-Exposure Prophylaxis (PrEP) with daily tenofovir/emtricitabine safely provides high levels of protection against HIV infection if taken correctly and has expanded the HIV prevention landscape. Global PrEP uptake has been slower than expected, however, and PrEP acceptability among men who have sex with men (MSM) is only 58%. Promoting PrEP requires innovative, tailored approaches grounded in contextualized understanding of the social context and lived experiences of potential users. Among MSM, multiple levels of intersecting stigma related to HIV and sexual orientation can deter PrEP initiation. PrEP stigma, which includes negative stereotypes of PrEP users as having HIV and/or being irresponsible and promiscuous, also greatly inhibits PrEP acceptability and uptake. More research on levels and manifestations of PrEP stigma are needed to inform global PrEP promotion efforts. Mobile Health (mHealth) interventions, in particular smartphone applications (apps), can be used to mitigate stigma. The accessibility, affordability, flexibility, and anonymity of smartphones make them a highly appealing medium for engaging MSM and addressing PrEP stigma. Further, smartphone interventions address issues such as transportation logistics, stigma, and confidentiality, all of which are barriers to sexual health services among MSM in Guatemala. While still a nascent field, early evidence, including work by our team, suggests that smartphone apps can address stigma as a barrier to health promotion among MSM by providing information and cultivating social support. Our community research partner, Colectivo Amigos Contra el SIDA (CAS), opened the first community-based PrEP clinic in Latin America in January 2016 and is now planning to scale up coverage. This scale up creates a crucial need for information on barriers to PrEP acceptability and uptake and a unique opportunity to explore PrEP stigma in the lives of MSM. The proposed R21 aims to assess the role of stigma in PrEP acceptability to inform the design of mHealth PrEP promotion strategies through a bidirectional process of research capacity building with UNC and CAS. In Aim 1, we will determine the association between PrEP stigma and PrEP acceptability among MSM using a mixed methods approach. We will conduct qualitative in-depth interviews (n=20) and a structured survey (n=200) to obtain multiple perspectives on PreP acceptability, PrEP stigma, and smartphone use and preferences. For Aim 2, we will assess how MSM in Guatemala interact in online discussions and exchange social support related to PrEP through online focus groups discussions. For Aim 3, we will evaluate strategies to promote uptake of and engagement with a smartphone app for PrEP uptake. In these discussions we will assess optimal channels and messaging for app dissemination and components within the app to promote engagement.
项目总结/文摘

项目成果

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CLARE L BARRINGTON其他文献

CLARE L BARRINGTON的其他文献

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{{ truncateString('CLARE L BARRINGTON', 18)}}的其他基金

Understanding burden and lived experience of diabetes and hypertension among women living with HIV in the Dominican Republic to improve care integration
了解多米尼加共和国艾滋病毒感染者的糖尿病和高血压负担和生活经历,以改善护理一体化
  • 批准号:
    10538201
  • 财政年份:
    2022
  • 资助金额:
    $ 16.94万
  • 项目类别:
Understanding burden and lived experience of diabetes and hypertension among women living with HIV in the Dominican Republic to improve care integration
了解多米尼加共和国艾滋病毒感染者的糖尿病和高血压负担和生活经历,以改善护理一体化
  • 批准号:
    10653263
  • 财政年份:
    2022
  • 资助金额:
    $ 16.94万
  • 项目类别:
Piloting a multi-level intervention to promote viral suppression among transgender women living with HIV
试点多层次干预措施,促进感染艾滋病毒的跨性别女性的病毒抑制
  • 批准号:
    10676883
  • 财政年份:
    2022
  • 资助金额:
    $ 16.94万
  • 项目类别:
Piloting a multi-level intervention to promote viral suppression among transgender women living with HIV
试点多层次干预措施,促进感染艾滋病毒的跨性别女性的病毒抑制
  • 批准号:
    10548552
  • 财政年份:
    2022
  • 资助金额:
    $ 16.94万
  • 项目类别:
Patient and Provider perspectives on long acting injectable ART
患者和医疗服务提供者对长效注射 ART 的看法
  • 批准号:
    10116481
  • 财政年份:
    2019
  • 资助金额:
    $ 16.94万
  • 项目类别:
PrEP Up!: Understanding PrEP stigma to improve uptake among men who have sex with men
PrEP Up!:了解 PrEP 耻辱以提高男男性行为者的接受度
  • 批准号:
    9754300
  • 财政年份:
    2019
  • 资助金额:
    $ 16.94万
  • 项目类别:
Patient and Provider perspectives on long acting injectable ART
患者和医疗服务提供者对长效注射 ART 的看法
  • 批准号:
    10589878
  • 财政年份:
    2019
  • 资助金额:
    $ 16.94万
  • 项目类别:
Patient and Provider perspectives on long acting injectable ART
患者和医疗服务提供者对长效注射 ART 的看法
  • 批准号:
    10437594
  • 财政年份:
    2019
  • 资助金额:
    $ 16.94万
  • 项目类别:

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针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
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Targeted interventions to address the multi-level effects of gender-based violence on PrEP uptake and adherence among adolescent girls and young women in Kenya
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