A Mind-Body Intervention to reduce symptoms among people aging with HIV

修订的项目摘要：减少艾滋病毒老年患者症状的身心干预(1 R34 AT009966-01) 项目摘要 在美国，一半的艾滋病毒感染者年龄在50岁以上；预计到2020年，这一比例将增加到70%。然而，针对感染艾滋病毒/艾滋病的老年人，很少有针对心理症状的干预措施，也没有针对身体症状的干预措施，这两种症状在这一人群中都很普遍。需要找到创新和可获得的干预措施，帮助感染艾滋病毒/艾滋病的老年人控制其症状。像太极和启功(TCQ)这样的身心干预措施，可以改善身体和心理健康。TCQ是一系列缓慢的、低影响的冥想运动，结合了呼吸、冥想和姿势。我们建议对患有艾滋病毒/艾滋病的不同种族老年人进行标准化的TCQ干预措施的改进、适应、可接受性和可行性测试，该干预措施对癌症患者有效，目的是增强他们管理心理和身体症状的能力。因此，这项研究提出了三个目标：(I)完善和在文化上调整TCQ干预方案，以适应不同样本的艾滋病毒/艾滋病患者(50岁或以上)；(Ii)评估TCQ干预的可接受性，假气功控制条件，以及老年艾滋病毒/艾滋病患者(n=60)护理控制条件的标准；以及(Iii)评估TCQ干预和假气功控制条件的可行性。参与者将从佛罗里达州迈阿密的一家具有联邦资格的健康中心招募。TCQ干预的适应是第一个目标，将通过定性研究进行。将进行专家小组讨论、主要线人访谈和三个焦点小组，并通过基于主题的内容分析进行分析。为了解决目标2和目标3，我们将进行一项先导性研究；参与者将被随机分为3种情况：TCQ干预、假气功情况或标准护理情况。我们将通过问卷调查和遵守TCQ来评估可接受性和可行性。结果将在基线、干预后2周和3个月随访时进行评估。对结果的分析将包括满足可行性和可接受性的具体先验基准，从80%到90%不等。此外，评估将包括基于参与者和培训者的衡量标准，例如干预保真度清单的使用。这项研究解决了感染艾滋病毒/艾滋病的老年人获得自我管理心理和身体症状的技能的重要需要，这两种症状在这一人群中都很普遍。

Revised Project Summary: A Mind-Body intervention to reduce symptoms among people aging with HIV (1 R34 AT009966-01) Project Summary Half of those infected with HIV in the United States are over 50 years of age; this is expected to increase to 70% by 2020. Yet, few interventions exist for older people living with HIV/AIDS that address psychological symptoms, and none that address physical symptoms, both of which are prevalent in this population. There is a need to find innovative and accessible interventions that can help older people living with HIV/AIDS to manage their symptoms. Mind-body interventions, like Tai chi and Qi gong (TCQ), improves both physical and psychological health. TCQ is a series of slow, low-impact meditative movements that integrates breath work, meditation, and stances. We propose the refinement, adaptation, acceptability and feasibility testing of a standardized TCQ intervention shown efficacious with cancer patients, to an ethnically diverse population of older people living with HIV/AIDS, with the goal of enhancing their ability to manage psychological and physical symptoms. Thus, this study proposes three aims: (i) to refine and culturally adapt a TCQ intervention protocol for a diverse sample of older people living with HIV/AIDS (50 years of age or older); (ii) to evaluate the acceptability of the TCQ intervention, a sham qigong control condition, and a standard of care control condition for older people living with HIV/AIDS (n = 60); and (iii) to evaluate the feasibility of the TCQ intervention and sham qigong control condition. Participants will be recruited from a federally qualified health center in Miami, Florida. Adaptation of the TCQ intervention, the first aim, will be done through qualitative research. An expert panel discussion, key informant interviews, and three focus groups will be conducted, and analyzed by thematically based content analysis. To address aims 2 and 3 we will conduct a pilot study; participants will be randomized to one of 3 conditions: the TCQ intervention, a sham qigong condition, or a standard of care condition. We will assess acceptability and feasibility through questionnaires and adherence to TCQ. Outcomes will be assessed at baseline, 2-week post-intervention, and at three months follow up. Analysis of outcomes will include meeting specific a prori benchmarks for feasibility and acceptability, ranging from 80% to 90%. In addition, assessment will include measurements based on both participants and trainers, such as use of the intervention fidelity checklist. This study addresses an important need for older people living with HIV/AIDS to acquire skills to self-manage both psychological and physical symptoms, both of which are prevalent in this population.