Maternal gut microbiome during pregnancy influences offspring atopy and asthma.

怀孕期间母体肠道微生物组影响后代特应性和哮喘。

• 批准号: nhmrc : GNT1151322
• 负责人: Dr Lawrence Gray
• 金额: $ 4.6万
• 依托单位: Deakin University
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/maternal-gut-microbiome-atopy-asthma/1348983
• 关键词: Maternal; gut; microbiome; during; pregnancy

Allergic diseases such as food allergy and asthma have increased significantly as our exposure to bacteria has reduced. Many studies have explored exposure to bacteria in early life but few have examined the maternal bacteria we are exposed to while we develop in the womb. New studies indicate that we are exposed to many different components of our mothers gut bacteria and this might change our developing immune system and determine whether or not we get diseases like food allergy and asthma.

食物过敏和哮喘等过敏性疾病随着我们接触细菌的减少而显着增加。许多研究探讨了在生命早期暴露于细菌，但很少有人研究我们在子宫中发育时暴露于母体细菌。新的研究表明，我们暴露在母亲肠道细菌的许多不同成分中，这可能会改变我们发育中的免疫系统，并决定我们是否会患上食物过敏和哮喘等疾病。