Training in the Science of Co-Occurring Disorders

此更新申请提出了一个计划，以维持和加强一个独特的培训计划，在一个新兴的 跨学科研究领域，同时发生的物质使用和其他精神和医学疾病 （COD）。考虑到化学需氧量是一种常态，而不是例外， 那些有成瘾障碍的人。这个项目的理念是，为了有效地解决问题， 成瘾和其他常见的精神和健康疾病，人们必须充分意识到它们的共存， 病因学、现象学和临床表现。我们不断发展的计划利用独特的资源， 在达特茅斯的机会。五个不同的研究小组（技术和行为中心 健康，心理和脑科学系，诺里斯棉花癌症控制研究计划， 精神病学系的成瘾研究项目，以及实验和分子生物学项目。 医学神经科学）提供行为和神经生物学机制中以COD为重点的机会， 行为和药理学治疗的发展，技术辅助的评估创新， 治疗提供、实施科学以及卫生服务和政策。培训教师包括MD和 博士研究员具有培养年轻科学家的良好历史和杰出的校外记录 资助他们的研究项目。目前，我们的T32教师有24个NIH-，3个NSF-和1个PCRI- 资助的项目。在该计划的前4年（资金的初始周期），我们的培训名额有 我们仍然有高素质的受训人员，我们现在已经培训或正在培训4 博士前和7名博士后T-32资助的学员和另外两名参加我们项目的学员 而是由其他来源资助的这些学员撰写了75篇同行评审的出版物， 培训活动，是其中45%的第一作者。我们的学员在许多场合展示了他们的研究成果 国家和地方科学会议，除了两个已经完成了顶点项目在中学 有兴趣的领域与替代导师。所有已经或即将完成该计划的学员 继续从事研究密集型职位或继续进行下一步的研究培训， 成为独立的研究科学家。我们的评估过程产生了非常积极的反馈， 也导致了我们的培训计划的计划增强。本更新申请旨在维持 积极普查3名博士前和4名博士后学员。我们已经制定了一个修订的招聘计划 利用新的达特茅斯计划来解决我们在吸引和招生方面的持续困难， 少数民族的弱势群体。总体而言，T32供资的第一个周期导致了 成功地制定和实施一项有力的培训计划，有效地培养年轻人 科学家参与合作和跨学科研究，包括和解决共同的问题， 存在成瘾和其他精神和健康障碍。

This renewal application proposes a plan to sustain and enhance a unique training program in an emerging area of trans-disciplinary research, co-occurring substance use and other psychiatric and medical disorders (COD). The need for this scientific focus is vital given that COD are more the norm than the exception among those with addictive disorders. The philosophy of this program charges that to effectively impact the problems of addiction and other common psychiatric and health disorders, one must be fully aware of their co-existence, etiologies, phenomenology, and clinical manifestations. Our evolving program leverages unique resources and opportunities available at Dartmouth. Five diverse research groups (Center for Technology and Behavioral Health, Department of Psychological and Brain Sciences, Norris Cotton Cancer Control Research Program, the Department of Psychiatry’s Addiction Research Program, and the Program of Experimental and Molecular Medicine-Neuroscience) provide COD-focused opportunities in behavioral and neurobiological mechanisms, behavioral and pharmacological treatment development, technology-assisted innovations in assessment and treatment delivery, implementation science, and health services and policy. Training faculty include MD and PhD investigators with strong histories of training young scientists and outstanding records of extramural funding to support their research programs. Currently our T32 faculty have 24 NIH-, 3 NSF-, and 1 PCORI- funded projects. During the first 4 years of this program (the initial cycle of funding), our training slots have remained at capacity with high quality trainees, and we have now trained or are in the process of training 4 predoctoral and 7 postdoctoral T-32 funded trainees and two other trainees who participated in our program but were funded by other sources. These trainees have authored 75 peer-reviewed publications related to their training activities and were first author on 45% of these. Our trainees have presented their research at many national and local scientific conferences, and all but two have completed capstone projects in a secondary area of interest with an alternative mentor. All the trainees who have or are about to complete the program continue in research intensive positions or have continued in the next step of research training towards becoming independent research scientists. Our evaluation process has yielded highly positive feedback, and also resulted in planned enhancements to our training program. This renewal application proposes to maintain an active census of 3 predoctoral and 4 postdoctoral trainees. We have developed a revised a recruitment plan that takes advantage of new Dartmouth initiatives to address our continued difficulty attracting and enrolling underrepresented minorities to the program. Overall, the first cycle of T32 funding has resulted in the successful development and implementation of a vigorous training program that is effectively preparing young scientists to engage in collaborative and transdisciplinary research that embraces and addresses the co- existence of addiction and other psychiatric and health disorders.