African Centre for Biostatistical Excellence

项目摘要 LMIC：南非 机构：斯泰伦博斯大学，开普敦 科学领域：HIV研究设计和方法的生物统计学 非洲生物统计卓越中心：建设艾滋病毒/艾滋病生物统计能力 研究 此应用程序是在响应FOA“福格蒂艾滋病毒研究培训计划的低收入和中等收入 根据D43赠款机制（FOA PAR-16-279）， 建立艾滋病毒研究设计和方法的生物统计能力，并建立非洲艾滋病中心， 南非斯泰伦博斯大学的生物统计学卓越奖（ACBE）。 在撒哈拉以南非洲建立一个可持续的、多学科的卫生研究企业， 这对改善该地区的健康、促进发展和推进科学至关重要。SSA 与世界其他地区相比，中国继续承受着不成比例的艾滋病毒/艾滋病和结核病负担 这导致了更多的预防计划和研究活动，以试图阻止这种流行病。的 艾滋病毒/艾滋病和结核病研究活动的增长创造了对训练有素的方法学家的需求，他们可以 促进研究的设计、实施、分析和报告，并提供指导和培训 下一代研究人员的未来。当地培训的方法学家，包括流行病学家、社会科学家 许多非洲国家现在都有卫生经济学家（程度较轻）。然而，尽管各种 尽管在撒哈拉以南非洲开展了许多努力，但生物统计专业知识仍然严重短缺。生物统计学家是 研究团队需要他们的技能，在写作竞争性赠款，执行统计程序， 进行先进的数据分析，在知名期刊上发表文章，并在 研究生水平。 为了满足对生物统计专家的需求，我们建议设立非洲生物统计卓越中心 （ACBE）在斯泰伦博斯大学与一个使命，以实施高质量的生物统计学培训计划 满足斯泰伦博斯大学（SU）和SSA地区的艾滋病毒研究需求和竞争力。的 该培训补助金的具体目标是：（1）通过正式的硕士课程建立生物统计能力 斯泰伦博斯大学的学术课程;（2）在生物医学研究人员中建立生物统计学素养 通过在撒哈拉以南非洲的短期课程;（3）通过专业的生物统计学教学能力， 研讨会和工作人员发展计划;（4）建立非洲生物统计卓越中心; 生物统计卓越中心是对福格蒂建立可持续发展战略计划的直接回应。 通过卓越研究中心的研究环境。这些研究“中心”是一种丰富和 通过将一个机构与一个国家和一个区域内的其他地点联系起来，维持该机构的研究能力。 我们提出的ACBE将补充整个非洲艾滋病毒/艾滋病和结核病研究其他领域的培训工作。 撒南地区。

PROJECT SUMMARY LMIC: South Africa Institution: Stellenbosch University, Cape Town Scientific Area: Biostatistics for HIV research design and methodology Africa Center for Biostatistical Excellence: Building Biostatistics Capacity for HIV/AIDS Research This application is in response to the FOA “Fogarty HIV Research Training Program for Low- and Middle-Income Country Institutions” under the D43 grant mechanism (FOA PAR-16-279) and requests 5 years of support to build biostatistics capacity for HIV research design and methodology and establish an Africa Center for Biostatistical Excellence (ACBE) at Stellenbosch University in South Africa. The creation of a sustainable, multidisciplinary health research enterprise in Sub-Saharan Africa (SSA) is of paramount importance for improving health, promoting development and advancing science in the region. SSA continues to experience a disproportionate burden of both HIV/AIDS and TB relative to the rest of the world that has led to increases prevention programs as well as research activities to try and stop the pandemic. The growth in HIV/AIDS and TB research activities has created a demand for well-trained methodologists who can contribute to the design, conduct, analysis and reporting of research studies and provide mentoring and training of the next generation of researchers. Locally trained methodologists, including epidemiologists, social scientists and (to a lesser extent) health economists are now available in many African countries. However, despite various efforts in SSA, there remains a critical shortage of biostatistics expertise. Biostatisticians are integral members of research teams required for their skills in writing competitive grants, executing statistical procedures, conducting advanced data analysis, publishing in high profile journals and teaching biostatistics at the postgraduate level. To meet the demand for biostatistical experts, we propose to setup an Africa Center for Biostatistical Excellence (ACBE) at Stellenbosch University with a mission to implementing high quality training programs in biostatistics to meet the HIV research needs and competitiveness of both Stellenbosch University (SU), and SSA region. The specific objectives of this training grant are to: (1) to build biostatistics capacity through a formal Master level academic program at Stellenbosch University; (2) to build biostatistical literacy among biomedical researchers through short courses in Sub-Saharan Africa; (3) to develop biostatistics teaching capacity through specialized seminars and staff development programs; (4) to setup the Africa Center for Biostatistical Excellence; A Center for Biostatistical Excellence is a direct response to one of Fogarty’s strategic plan of building sustainable research environments through centers of research excellence. These research “hubs” are a way to enrich and sustain the research capacity of an institution by linking it to other sites within a country and across a region. Our proposed ACBE will complement training efforts in other areas of HIV/AIDS and TB research across the SSA region.