Data Analysis and Management Core

数据分析与管理核心

• 批准号: 10198678
• 负责人: Raphael Gottardo
• 金额: $ 138.56万
• 依托单位: SEATTLE CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-19 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10198678
• 关键词: Age; Attention; Bioconductor; Biological; Biological Assay; Cells; Collaborations; Collection; Communicable Diseases; Communities; Complex; Computer Analysis; Data; Data Analyses; Data Collection; Data Files; Data Management Resources; Data Set; Database Management Systems; Databases; Deposition; Doctor of Philosophy; Ensure; Fostering; Fred Hutchinson Cancer Research Center; HIV Infections; HIV immunization; Immune response; Immune system; Immunologics; Immunology procedure; Infrastructure; Lead; Linear Models; Measures; Modeling; Preparation; Process; Quality Control; Reproducibility; Research; Research Design; Research Project Grants; Resources; Running; Science; Scientist; Services; Software Tools; Standardization; Statistical Data Interpretation; System; Systems Biology; Technology; Testing; Time; Tissues; Vaccines; Work; analysis pipeline; base; bioinformatics infrastructure; data analysis pipeline; data integration; data management; data quality; data sharing; data standards; data submission; database schema; heterogenous data; improved; insight; malaria infection; member; novel; pathogen; programs; software development; task analysis; tool; web portal

Raphael Gottardo, Ph.D., of Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, will serve as project leader for the subaward of the entitled application. Through this work, Dr. Gottardo's team will set up a data management core to permit data to be stored, quality controlled, standardized, analyzed and submitted to the ImmPort database. The core will also provide basic standard support for all research projects to be undertaken through the U19. The work consists of: · Developing a central data management system for collection, storage and sharing of data. · Developing tools to quality control, standardize and annotate raw data to facilitate submission to ImmPort. · Developing standardized data analysis pipelines for common assay technologies. · Providing basic study design and statistical support. All data for analysis under this Scope of Work will be de-identified without the key to decode.

Raphael Gottardo博士，弗雷德·哈钦森癌症研究中心疫苗和传染病部 中心，西雅图，华盛顿州，将担任项目负责人的子奖项的有资格的申请。通过这项工作， 博士Gottardo的团队将建立一个数据管理核心，以允许数据存储，质量控制， 标准化，分析并提交给ImmPort数据库。核心还将提供基本标准 支持通过U19开展的所有研究项目。这项工作包括： ·开发一个中央数据管理系统，用于收集、储存和分享数据。 ·开发质量控制、标准化和注释原始数据的工具，以方便提交给ImmPort。 ·为常见的分析技术开发标准化的数据分析管道。 ·提供基本的研究设计和统计支持。 本工作范围内用于分析的所有数据将被去识别化，没有解码密钥。