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Vascular Surgery Research Training Program

血管外科研究培训计划

基本信息

批准号：
10199882
负责人：
JON STEVEN MATSUMURA
金额：
$ 23.86万
依托单位：
UNIVERSITY OF WISCONSIN-MADISON
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-05-01 至 2023-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10199882
关键词：
Blood Vessels Operative Surgical Procedures Research Training Training Programs

项目摘要

PROJECT SUMMARY/ABSTRACT Cardiovascular disease remains the leading cause of mortality and morbidity in the US. The growth of the aged population over the next 20 years will dramatically increase the incidence of peripheral vascular disease (PVD) leading to a great need for new options for diagnosis, prevention and treatment. There is a relative deficit in the number of researchers whose investigations focus exclusively on peripheral vascular disease and this T32 training program is designed to train basic scientists, engineers, and clinicians who can advance the science and create new therapies for PVD. This application requests continued support for a multidisciplinary and collaborative program that co-trains young physician/scientists and PhDs with an interest in vascular disease. The overall goal of the proposed “Vascular Surgery Research Training Program” is to provide comprehensive research training to scientists who are strongly motivated to develop a career in vascular surgery and vascular research. The program provides trainees with multiple opportunities for research activities in broad areas of vascular biology, drug development and delivery, and health services research. The program also fosters the development of knowledge, competence, skills, professional attitudes, and experience required for successful academic careers in independent NIH-funded research. The specific objectives of this program are to: 1) for selected surgical residents interested in vascular surgery, provide training in the conduct of basic, translational or health services research through participation in an individualized mentoring program, 2) develop physician-scientists and leaders in academic surgery with expertise in vascular research, 3) expand the pool of surgeon-scientists with comprehensive training in health services research, 4) expand the pool of PhD scientists who will devote their careers to vascular related research, and 5) foster an environment of collaboration between clinician-scientists and PhDs that enhances the breadth of vascular research. The program includes a pool of outstanding extramurally funded trainers from a variety of vascular- related disciplines including surgery, population health, regenerative medicine, pathology and engineering. The program has had tremendous success over its initial four years. Interest in the program has been robust with the ratio of able applicants to those accepted of over 12:1. All of the trainees have had a robust research experience working closely with a collaborative research team. Four trainees have completed the program and are continuing their training in environments that will fasciliate their continued success in developing an independent academic career with a focus on vascular disease. An additional four are currently appointed. Trainees have demonstrated tremendous productivity as evidenced by publications and national presentations. We feel that this program over time will contribute greatly to the work force of able researchers that will make transformative discoveries in the field of vascular disease. We therefore request continued funding for an additional five years and an increase in the positions from 4 to 6.

项目总结/文摘

项目成果

期刊论文数量（57）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

TGF-β/Smad3 stimulates stem cell/developmental gene expression and vascular smooth muscle cell de-differentiation.

DOI：
10.1371/journal.pone.0093995
发表时间：
2014
期刊：
PloS one
影响因子：
3.7
作者：
Shi X;DiRenzo D;Guo LW;Franco SR;Wang B;Seedial S;Kent KC
通讯作者：
Kent KC

Controlled Self-assembly of Stem Cell Aggregates Instructs Pluripotency and Lineage Bias.

DOI：
10.1038/s41598-017-14325-9
发表时间：
2017-10-25
期刊：
Scientific reports
影响因子：
4.6
作者：
Xie AW;Binder BYK;Khalil AS;Schmitt SK;Johnson HJ;Zacharias NA;Murphy WL
通讯作者：
Murphy WL

Inter-rater agreement and checklist validation for postoperative wound assessment using smartphone images in vascular surgery.

DOI：
10.1016/j.jvsv.2016.02.001
发表时间：
2016-07
期刊：
Journal of vascular surgery. Venous and lymphatic disorders
影响因子：
0
作者：
Wiseman JT;Fernandes-Taylor S;Gunter R;Barnes ML;Saunders RS;Rathouz PJ;Yamanouchi D;Kent KC
通讯作者：
Kent KC

Know Your Limitations: Assumptions in the Single-Beat Method for Estimating Right Ventricular-Pulmonary Vascular Coupling.

了解您的局限性：估计右心室-肺血管耦合的单搏法中的假设。