Palliative Care Research Cooperative Group (PCRC): Measurement Core

项目概要/摘要 此U2 C应用程序的主要目标是提高姑息治疗的生产率和影响力 研究合作组（PCRC）通过促进高质量，有效的临床研究的进行 扩大进行多点临床试验的姑息治疗研究人员的数量和专业知识。在 追求这些总体目标和目的，测量核心，PCRC内的四个核心之一， 致力于通过确保高质量的测量科学和患者， 在所有PCRC支持的研究方案中以结果为中心，并通过促进研究者的发展， 测量科学培训。衡量核心的具体目标是：（1）继续扩大 PCRC仪器库，以满足EOLPC研究的新需求;（2）促进开发和 验证满足EOLPC研究需求的工具，特别关注代表性不足的问题 少数民族和经济上处于不利地位的人，患有多种慢性病的人，以及儿童 （3）领导审查、修订和扩大《人口与发展报告》的共同数据要素， 与其他核心（数据，信息学和统计学;护理人员研究;和临床 研究/方法）;（4）与其他三个核心合作，在研究之间建立一致性， 与事件协调中心磋商，促进各核心之间的协同作用;及（5）与调查员紧密合作 发展中心，指导和培训PCRC成员严格使用和发展措施， 他们的研究设计衡量核心的具体目标和战略旨在提供一个 在方法上严格和多方面的方法，以满足EOLPC研究的测量需求。

PROJECT SUMMARY/ABSTRACT The primary goals of this U2C application are to increase the productivity and impact of the Palliative Care Research Cooperative Group (PCRC) through facilitating conduct of high-quality, effective clinical research and expanding the number and expertise of palliative care researchers conducting multi-site clinical trials. In pursuit of these overall goals and objectives, the Measurement Core, one of four Cores within the PCRC, strives to facilitate progress in EOLPC research by ensuring high quality measurement science and patient- centered outcomes in all PCRC supported research protocols, and by promoting investigator development and training in measurement science. The Measurement Core's specific aims are: (1) to continue to expand the PCRC Instrument Library to meet emerging needs of EOLPC research; (2) to foster the development and validation of instruments that meet the needs of EOLPC research, with a particular focus on underrepresented minorities and those who are economically disadvantaged, those with multiple chronic conditions, and pediatric populations; (3) to lead the review, revision and expansion of the PCRC Common Data Elements in collaboration with other Cores (Data, Informatics, and Statistics; Caregiver Research; and Clinical Studies/Methodology); (4) to collaborate with the other three Cores to create consistency across studies that consult with the PCRC and promote synergy among the Cores; and (5) to work closely with the Investigator Development Center to mentor and train PCRC members in the rigorous use and development of measures in their study design. The Measurement Core specific aims and strategies are intended to provide a methodologically rigorous and multi-faceted approach to meeting the measurement needs of EOLPC research.