Developmental Core

核心B：发展 摘要 发展核心(核心B)是宾夕法尼亚大学CFAR活动的基石，催化新的研究方向 在艾滋病毒/艾滋病优先领域，通过指导计划加强研究渠道，确保下一步 新一代艾滋病毒研究人员和研究带头人，并吸引新的艾滋病研究人员，并取得进展 宾夕法尼亚大学CFAR战略科学优先事项。发展的核心是建立新的 独立的艾滋病毒/艾滋病调查人员和新的研究领域，通过其指导、伙伴关系和资助活动。 核心基金自1999年成立以来，已资助101笔试验拨款，总额达396万元，所得款项达8240万元 在随后的NIH基金中，投资回报率(ROI)为21：1；在过去10年中，它为62 试点拨款250万美元，导致NIH拨款总额为6240万美元(25：1 ROI)。核心B由巴勃罗博士领导 特巴斯(董事)和路易斯·蒙塔纳(联席董事)。发展的核心目标是： 1.培训和指导下一代艾滋病毒研究人员和艾滋病研究带头人，鼓励 让来自其他领域的资深研究人员进入艾滋病毒/艾滋病研究领域，并增强 该领域的研究人员通过：(1)教育、指导和合作计划提供建议、支持 以及对新出现的和新接触艾滋病的调查人员的领导；(2)让CFAR社区广泛参与 通过与其他核心和CFAR教职员工的协作和协调进行指导；(3)实施一系列 研讨会、工作组和审查小组将来自相关领域的调查人员聚集在一起 以便向新的研究人员提供反馈，并促进跨学科互动。 2.提供新颖的资助机制，以支持创新研究计划，并作为 通过以下方式为研究培训提供工具：(1)发展试点资助计划，资助最多6 每年的发展项目，目标是新的和新接触艾滋病毒的调查人员，和/或新的跨学科 团队；(2)伙伴关系试点资助计划，利用资源并在以下方面与其他小组产生协同效应 CFAR园区；(3)为初级调查人员提供灵活、快速资金的新小额赠款计划 为重新提交赠款或支持在重要科学会议上的陈述而获得有针对性的数据。 3.促进CFAR和美国国立卫生研究院艾滋病毒/艾滋病研究优先领域的研究，并制定 跨学科协作研究，并通过以下方式吸引校园和社区合作伙伴：(1)创建 聚集基础、临床和行为科学研究人员的环境；(2)吸引 校园研究人员和费城社区合作伙伴与学校、部门和部门进行接触 并加强与费城公共卫生和社区部门的合作- 以艾滋病为基础的服务组织；(3)指导指导活动和资助倡议，以支持新的 调查人员并在艾滋病毒/艾滋病优先研究领域发展职业；(4)指导筹资倡议，以 CFAR包括其科学工作组的优先领域。

Core B: Developmental ABSTRACT The Developmental Core (Core B) is the keystone of Penn CFAR activities catalyzing new research directions in HIV/AIDS priority areas, enhancing the research pipeline through mentoring programs that ensure the next generation of HIV investigators and research leaders and attracting new-to-AIDS investigators, and advancing Penn CFAR strategic scientific priorities. The Developmental Core has been critical for the establishment of new independent HIV/AIDS investigators and new research areas by its mentoring, partnering and funding activities. Since creation of the Core in 1999, it has funded 101 pilot grants with a total of $3.96M, yielding $82.4M in subsequent NIH funds for a 21:1 return on investment (ROI); over the past 10 years it has funding 62 pilot grants with $2.5M, resulting in NIH grants totaling $62.4M (25:1 ROI). Core B is led by Drs. Pablo Tebas (Director) and Luis Montaner (Co-Director). The Developmental Core aims are: 1. To train and mentor the next generation of HIV investigators and leaders in AIDS research, encourage entry of established investigators from other areas into HIV/AIDS research, and enhance the diversity of investigators in the field through: (1) Education, mentoring, and partnering programs to provide advice, support and leadership for emerging and new-to-AIDS investigators; (2) Broadly engaging the CFAR community in mentoring through collaboration and coordination with other Cores and CFAR faculty; (3) Implementing a series of Workshops, Working Groups, and Review Panels that bring together investigators from interrelated areas in order to give feedback to new investigators and to nurture interdisciplinary interactions. 2. To provide novel funding mechanisms that support innovative research initiatives, and serve as a vehicle for research training through: (1) The Developmental Pilot Grant program that funds up to 6 developmental projects each year, targeting new and new-to-HIV investigators, and/or new interdisciplinary teams; (2) A Partnership Pilot Grant program that leverage resources and create synergy with other groups on the CFAR campus; (3) A novel Microgrant Grant Program to provide nimble, rapid funding for junior investigators to obtain targeted data for resubmission of a grant or support presentations at important scientific meetings. 3. To catalyze research in CFAR and NIH HIV/AIDS research priority areas and the development of interdisciplinary collaborative research, and engage campus and community partners by: (1) Creating an environment that brings together investigators from the basic, clinical and behavioral sciences; (2) Engaging campus researchers and Philadelphia community partners in outreach to Schools, Departments and Divisions on campus, and enhancing collaborations with the Philadelphia Department of Public Health and community- based AIDS service organizations; (3) Directing mentorship activities and funding initiatives to support new investigators and to develop careers in HIV/AIDS priority research areas; (4) Directing funding initiatives to priority areas for the CFAR including its Scientific Working Groups.