Renal Control of Body Composition and Blood Pressure

摘要 这是美国加州大学肾脏研究博士后培训计划的续展申请书。 德克萨斯西南医学中心(德克萨斯州西南大学)。该计划为成年人和青少年提供研究培训 儿科肾病研究员以及从事肾脏相关研究的基础科学家。 该计划的目的仍然是培训对翻译感兴趣的内科科学家或基础科学家 研究谁将研究肾脏生物学和疾病，并将这些知识转化为对 病人护理。在过去的35年里，该培训计划一直得到持续资助。申请者名单为 稳健，而且该计划一直在填满。该项目的毕业生发表了重要的 对生物医学研究的贡献，许多人获得了教职并获得了外部资助 用于他们的研究。该计划的教职员工包括33名内科科学家和基础科学家，他们在 与肾脏相关的广泛的科学学科。培训计划分为三个部分 基础科学研究领域(肾脏生理学和细胞生物学、肾脏疾病病理生理学和 遗传学与发育)和以患者为中心的三个研究领域(慢性肾脏疾病、高血压 和心血管疾病、矿物质代谢)。每个项目都包括临床和基础科学学院。 以及正式的教学课程，其中包括伦理和负责任的研究行为方面的必修课， 以及由培训人员介绍的正在进行的工作研讨会系列。基础科学研究课程 还包括职业发展的专题，期刊俱乐部，以及西南大学的选修课 生物医学研究生院。以患者为中心的研究课程包括一项认证 以病人为中心的研究课程和临床科学硕士学位。该计划的实习生也 受益于德克萨斯大学西南乔治·M·奥布莱恩·肯尼提供的教育充实计划 研究核心中心，包括两周一次的研究会议、年度研讨会和实践 教授小鼠模型、小动物生理学、细胞生物学和病理学，以及临床和翻译 研究。

Abstract This is an application for continuation of the postdoctoral training program in kidney research at the University of Texas Southwestern Medical Center (UT Southwestern). The program provides research training for adult and pediatric nephrology fellows as well as basic scientists who are conducting kidney-related research.The primary purpose of the program remains the training of physician-scientists or basic scientists interested in translational research who will investigate kidney biology and disease, and transform this knowledge into improvements in patient care. The training program has been continuously funded for the past 35 years. The applicant pool is robust, and the program has filled consistently. The graduates from the program have published important contributions to biomedical research, and many have obtained faculty positions and received external funding for their research. The program faculty comprises 33 physician-scientists and basic scientists with expertise in a broad range of scientific disciplines that are relevant to the kidney. The training program is organized into three areas in basic science research (Renal Physiology & Cell Biology, Pathophysiology of Renal Disease, and Genetics & Development) and three areas in patient-oriented research (Chronic Kidney Disease, Hypertension & Cardiovascular Disease, and Mineral Metabolism). Each program includes clinical and basic science faculty and a formal didactic curriculum that includes required courses in ethics and the responsible conduct of research, and a works-in-progress seminar series presented by the trainnes. The curriculum for basic science research also includes special topics in career development, a journal club, and elective courses at the Southwestern Graduate School of Biomedical Sciences. The curriculum for patient-oriented research consists of a certification program in patient-oriented research and a Masters Degree in Clinical Science. Trainees in the program also benefit from the Educational Enrichment Program provided by the UT Southwestern George M. O'Brien Kidney Research Core Center, which includes a biweekly research conferences, an annual symposium, and hands-on instruction in mouse models, small animal physiology, cell biology and pathology, and clinical and translational research.