Renal Control of Body Composition and Blood Pressure

肾脏控制身体成分和血压

• 批准号: 10210383
• 负责人: MICHEL GERARD BAUM
• 金额: --
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10210383
• 关键词: Blood Pressure; Body Composition; Kidney

Abstract This is an application for continuation of the postdoctoral training program in kidney research at the University of Texas Southwestern Medical Center (UT Southwestern). The program provides research training for adult and pediatric nephrology fellows as well as basic scientists who are conducting kidney-related research.The primary purpose of the program remains the training of physician-scientists or basic scientists interested in translational research who will investigate kidney biology and disease, and transform this knowledge into improvements in patient care. The training program has been continuously funded for the past 35 years. The applicant pool is robust, and the program has filled consistently. The graduates from the program have published important contributions to biomedical research, and many have obtained faculty positions and received external funding for their research. The program faculty comprises 33 physician-scientists and basic scientists with expertise in a broad range of scientific disciplines that are relevant to the kidney. The training program is organized into three areas in basic science research (Renal Physiology & Cell Biology, Pathophysiology of Renal Disease, and Genetics & Development) and three areas in patient-oriented research (Chronic Kidney Disease, Hypertension & Cardiovascular Disease, and Mineral Metabolism). Each program includes clinical and basic science faculty and a formal didactic curriculum that includes required courses in ethics and the responsible conduct of research, and a works-in-progress seminar series presented by the trainnes. The curriculum for basic science research also includes special topics in career development, a journal club, and elective courses at the Southwestern Graduate School of Biomedical Sciences. The curriculum for patient-oriented research consists of a certification program in patient-oriented research and a Masters Degree in Clinical Science. Trainees in the program also benefit from the Educational Enrichment Program provided by the UT Southwestern George M. O'Brien Kidney Research Core Center, which includes a biweekly research conferences, an annual symposium, and hands-on instruction in mouse models, small animal physiology, cell biology and pathology, and clinical and translational research.

摘要 这是一份申请继续在肾脏研究大学的博士后培训计划， 德克萨斯西南医学中心（UT Southwestern）该计划为成年人提供研究培训， 儿科肾病学研究员以及进行肾脏相关研究的基础科学家。 该计划的目的仍然是培养对翻译感兴趣的医生科学家或基础科学家。 研究谁将调查肾脏生物学和疾病，并将这些知识转化为改善， 病人护理过去35年来，该培训计划一直得到持续资助。申请人池是 强大的，该计划一直充满。该计划的毕业生发表了重要的 为生物医学研究做出了贡献，许多人获得了教职并获得了外部资金 用于他们的研究。该计划的教师包括33名物理学家，科学家和基础科学家，他们在 与肾脏相关的广泛的科学学科。培训计划分为三个部分 基础科学研究领域（肾脏生理学和细胞生物学，肾脏疾病的病理生理学， 遗传学和发展）和三个面向患者的研究领域（慢性肾脏病，高血压 心血管疾病和矿物质代谢）。每个项目包括临床和基础科学教师 以及一个正式的教学课程，其中包括道德和负责任的研究行为的必修课程， 以及由培训人员举办的正在进行的系列研讨会。基础科学研究课程 还包括职业发展的专题，期刊俱乐部和西南大学的选修课程 生物医学科学研究生院。面向患者的研究课程包括一个认证 在以病人为导向的研究计划和临床科学硕士学位。该计划的学员还 受益于UT西南乔治M.奥布莱恩肾 研究核心中心，其中包括一个双周研究会议，年度研讨会，并动手 教学在小鼠模型，小动物生理学，细胞生物学和病理学，临床和翻译 research.

项目成果

Nonalcoholic fatty liver disease: a potential consequence of tumor necrosis factor-inhibitor therapy.

• DOI: 10.1097/meg.0000000000000421
• 发表时间: 2015-10
• 期刊: European journal of gastroenterology & hepatology
• 影响因子: 2.1
• 作者: Feagins LA;Flores A;Arriens C;Park C;Crook T;Reimold A;Brown G
• 通讯作者: Brown G

Potassium Magnesium Citrate Is Superior to Potassium Chloride in Reversing Metabolic Side Effects of Chlorthalidone.

柠檬酸钾镁在逆转氯噻酮的代谢副作用方面优于氯化钾。

• DOI: 10.1161/hypertensionaha.123.21932
• 发表时间: 2023
• 期刊: Hypertension (Dallas, Tex. : 1979)
• 作者: Vongpatanasin,Wanpen;Giacona,JohnM;Pittman,Danielle;Murillo,Ashley;Khan,Ghazi;Wang,Jijia;Johnson,Talon;Ren,Jimin;Moe,OrsonW;Pak,CharlesCY
• 通讯作者: Pak,CharlesCY

Association of Inflammatory Biomarkers with Immunosuppression Management and Outcomes in Kidney Transplant Recipients with COVID-19.

• DOI: 10.1016/j.transproceed.2021.08.002
• 发表时间: 2021-10
• 期刊: Transplantation proceedings
• 影响因子: 0.9
• 作者: AbdulRahim N;McAdams M;Xu P;Wojciechowski D;La Hoz RM;Lu C;Vazquez MA;Hedayati SS
• 通讯作者: Hedayati SS

Assessment of patient and provider attitudes towards therapeutic drug monitoring to improve medication adherence in low-income patients with hypertension: a qualitative study.

• DOI: 10.1136/bmjopen-2020-039940
• 发表时间: 2020-11-27
• 期刊: BMJ open
• 影响因子: 2.9
• 作者: Schesing KB;Chia R;Elwood B;Halm EA;Lee SJC;Lodhi H;Wu B;Sharma S;Smith SA;Jarrett RB;Das SR;Vongpatanasin W
• 通讯作者: Vongpatanasin W

Systemic lupus erythematosus diagnostics in the 'omics' era.

• DOI: 10.2217/ijr.13.59
• 发表时间: 2013-12-01
• 期刊: International journal of clinical rheumatology
• 作者: Arriens C;Mohan C
• 通讯作者: Mohan C