Using Implementation Science to Increase PrEP Uptake among African American Women in the South - HIV/AIDS Supplement

项目摘要/摘要 这项提议是为了回应：“#年艾滋病毒/艾滋病研究NIMHD奖的行政补充 经历健康差距的人群(非-MD-21-020)。母公司K01奖项旨在发展， 测试和评估面向美国南部社区医疗诊所工作人员的PrEP实施工具包 加强对美国南部非裔美国妇女的PrEP接触。为非裔美国妇女准备入学机会 在美国，可能会受到公共卫生突发事件和影响女性健康的社会结构性不平等的干扰 医疗体验和整体幸福感。这份行政副刊提出了一项解释性的 序贯混合方法设计评估以临床为基础的干预对以下人群PrEP摄取的影响 非裔美国女性。第一阶段：基线、2个月和4个月(N=300)的重复横断面调查 评估干预对患者水平PrEP摄取的影响(目标1)。第二阶段包括个别访谈，以 说明调查结果(目标2)。整合社会认知理论、社会压力理论和交叉性， 我们提议的混合方法研究将为干预对患者水平的影响提供重要证据 在国家突发公共卫生事件和社会结构性不平等的背景下取得的成果。调查结果来自 这项拟议的行政补充将加强临床干预对 在临床和非裔美国女性患者中提高PrEP的接受率。

Project Summary/Abstract This proposal is in response to: “Administrative Supplements to NIMHD Awards for Research on HIV/AIDS in Populations that Experience Health Disparities (NOT-MD-21-020).” The parent K01 award seeks to develop, test, and evaluate a PrEP Implementation Toolkit for staff in community healthcare clinics in the U.S. South to enhance PrEP access to African American women in the U.S. South. PrEP access for African American women in the U.S. may be disrupted by public health emergencies and sociostructural inequities influencing women’s healthcare experiences and overall wellbeing. This administrative supplement proposes an explanatory sequential mixed-methods design to assess the impact of a clinic-based intervention on PrEP uptake among African American women. Phase I: repeated cross-sectional surveys at baseline, 2- and 4-months (N=300) to assess the intervention’s impact on patient-level PrEP uptake (Aim 1). Phase II includes individual interviews to explicate survey findings (Aim 2). Integrating Social Cognitive theory, Social Stress theory and intersectionality, our proposed mixed-methods study will provide vital evidence of the intervention’s impact on patient-level outcomes within the context of national public health emergencies and sociostructural inequities. Findings from this proposed administrative supplement will strengthen the evidence of the clinical intervention’s impact to enhance PrEP uptake at both the clinic-level and among African American women patients.