Health Promotion and Disease Prevention Research Centers

癫痫患者面临着许多问题，包括复杂的药物治疗方案，生活方式， 调整，症状管理，耻辱，情绪困难，共病抑郁症，认知 贫困、残疾、失业或失业，以及交通工具有限。癫痫自我管理 可以改善PWE的治疗结果和整体生活质量。项目UPLIFT（使用实践和 学习增加有利的想法），管理癫痫好（MEW）网络自我管理 该计划是基于理论的，可以远程交付，并已被证明是有效的，在减少症状 共病抑郁症的比例然而，在经历过这种情况的社区中采用这种方案， 健康差距的最大负面影响一直很缓慢。黑人或非裔美国人， 大约三分之一的格鲁吉亚人口，携带更重的负担与癫痫相比， 白色同行，和项目UPLIFT在黑人成年人中的疗效现在才被调查。 目前拟议的项目将复制和评估项目UPLIFT的有效性与黑色的样本 成年癫痫患者，并确定关键的促进因素和障碍，在这一人群中采用。此外，本发明还 作为我们在MEW网络中的传播计划和贡献角色的一部分，我们建议支持 继续MEW网络综合数据库（MEW DB）计划，该计划使用档案数据进行 相关的二次分析，为癫痫自我管理的最佳实践提供信息。 通过社区参与的方式，我们建议的活动与SIP RFA的声明一致， 项目目标是：（1）利用文献和形成性研究的结果， 在整个研究过程中加强参与者招募和保留的策略;（2）探索和评估 患者相关因素的关联（例如，（3）对癫痫病患者进行治疗; 对现有的基于证据的MEW网络自我管理计划进行复制研究， UPLIFT，在格鲁吉亚的黑人癫痫患者中;以及（4）确定方案的有利因素和障碍 采用，参与和保留循证癫痫自我管理计划。 建议的研究将分三个阶段进行：（1）形成阶段，在此期间，我们将利用 焦点小组和深入访谈，以确定改善招聘和留住员工的战略， 了解非裔美国人癫痫患者的健康素养和癫痫健康知识;（2） 执行阶段，在此期间，我们建议复制和评估UPLIFT项目的功效， 减少非洲人的压力，焦虑和抑郁症状，癫痫发作频率和生活质量 美国人;和（3）传播阶段，在此期间，我们将与社区分享我们的发现 我们将与MEW网络数据库分享我们的数据。

People with epilepsy (PWE) face many problems including complicated medication regimens, lifestyle adjustments, management of symptoms, stigma, emotional difficulties, co-morbid depression, cognitive struggles, disability, under- or unemployment, and limited access to transportation. Epilepsy self-management can improve treatment outcomes and overall quality of life for PWE. Project UPLIFT (Using Practice and Learning to Increase Favorable Thoughts), a Managing Epilepsy Well (MEW) Network self-management program is theory-based, can be distance-delivered, and has been shown to be effective in reducing symptoms of co-morbid depression among PWE. However, adoption of such a program in communities that experience the greatest negative effects of health disparities has been slow. Black or African Americans, who constitute about a third of the population of Georgia, carry a heavier burden with regard to epilepsy compared to their White counterparts, and the efficacy of Project UPLIFT among Black adults is only now being investigated. The current proposed project will replicate and evaluate the efficacy of Project UPLIFT with a sample of Black adults with epilepsy and identify key facilitators and barriers to adoption among this population. Additionally, as part of our dissemination plan and contributory role in the MEW Network, we propose to support the continuation of the MEW Network integrated database (MEW DB) initiative that uses archival data to conduct relevant secondary analyses to inform best practice in epilepsy self-management. Using a community-engaged approach, our proposed activities are consistent with the SIP RFA's stated project objectives to: (1) utilize findings from the literature and formative research to incorporate recommended strategies for enhancing participant recruitment and retention throughout the study; (2) explore and evaluate associations of patient-related factors (e.g., health literacy) to inform best practices for the epilepsy field; (3) conduct a replication study of an existing evidenced-based MEW Network self-management program, Project UPLIFT, in Blacks with epilepsy across Georgia; and (4) identify enabling factors and barriers to program adoption, engagement and retention in evidence-based epilepsy self-management programs. The proposed study will be conducted in three phases: (1) a formative phase, during which we will utilize focus groups and in-depth interviews to identify strategies to improve recruitment and retention as well as understand health literacy and epilepsy health knowledge for African Americans with epilepsy; (2) an implementation phase, during which we propose to replicate and evaluate the efficacy of Project UPLIFT for reducing symptoms of stress, anxiety, and depression, seizure frequency and quality of life among African Americans; and (3) a dissemination phase, during which we will share our findings with community stakeholders and scientific outlets, and we will share our data with the MEW Network database.