Actions of the polyphenol epigallocatechin 3-gallate on insulin sensitivity

多酚表没食子儿茶素 3-没食子酸酯对胰岛素敏感性的作用

• 批准号: nhmrc : 1009962
• 负责人: A/Pr Michelle Keske
• 金额: $ 27.32万
• 依托单位: Antarctic Climate and Ecosystems CRC, University of Tasmania
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/actions-polyphenol-epigallocatechin-insulin-sensitivity/109447
• 关键词: Actions; polyphenol; epigallocatechin; gallate; insulin

This project will determine whether the bioactive compound in green tea (called EGCG) can reduce insulin resistance by enhancing the ability of insulin to open very small blood vessels (called capillaries) in muscle. Opening more capillaries will help glucose to be stored in muscle, thus alleviating insulin resistance. Findings from these studies may have important impact on the management of insulin resistance and type 2 diabetes.

该项目将确定绿茶中的生物活性化合物（称为 EGCG）是否可以通过增强胰岛素打开肌肉中非常小的血管（称为毛细血管）的能力来降低胰岛素抵抗。打开更多的毛细血管将有助于葡萄糖储存在肌肉中，从而减轻胰岛素抵抗。这些研究的结果可能对胰岛素抵抗和 2 型糖尿病的治疗产生重要影响。