AppalTRuST Project 3: Impact of proposed tobacco product rules in Appalachia on consumption and product switching with the Experimental Tobacco Marketplace

AppalTRuST 项目 3：阿巴拉契亚拟议烟草产品规则对实验烟草市场消费和产品转换的影响

• 批准号: 10665322
• 负责人: Mikhail Nikolaas Koffarnus
• 金额: $ 65.24万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-30 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10665322
• 关键词: Appalachian Region; Authorization documentation; Behavior; Biometry; Catchment Area; Cigarette; Cities; Communities; Community Outreach; Complex; Consumption; Data; Economics; Elasticity; Environment; Goals; Grant; Informatics; Manufacturer; Measures; Menthol; Methods; Modeling; Nicotine; Participant; Pattern; Policies; Price; Public Health; Randomized; Recommendation; Regulation; Research; Rural; Rural Appalachia; Rural Community; Sampling; Taxation; Tobacco; Tobacco use; United States Food and Drug Administration; Variant; abuse liability; authority; behavioral economics; combustible cigarette; design; falls; low nicotine content cigarette; nicotine user; patient engagement; peri-urban; prospective; recruit; rural area; rural underserved; rurality; tobacco products; tobacco regulation; tobacco regulatory science; urban area

ABSTRACT – Project 3 Our overall goal, reflecting AppalTRuST’s Integrative Theme of investigating the effects of regulatory changes on tobacco product use in Appalachian KY, is to assess the impact of proposed tobacco product regulations using behavioral economic methods that we have developed and refined in past years to characterize the consumption of tobacco products within the complex nicotine marketplace of Appalachian KY, a diverse and underserved rural region that would greatly benefit from focused tobacco regulatory science research. This project primarily falls under the Regulatory Scientific Domain of Impact Analysis. In 2009, the Food and Drug Administration (FDA) was granted authority to regulate tobacco products to benefit public health. In the years since, the FDA has proposed potential regulatory actions that may benefit public health, including regulating the maximum nicotine content in combustible cigarettes and restricting flavors of combusted and non- combusted tobacco products. Estimating the impact of any proposed regulatory action is complicated by the existence of a complex tobacco marketplace containing multiple products that are economic substitutes for one another and the frequent introduction of new tobacco products by manufacturers. Furthermore, when compared to more urban, non-Appalachian communities, rural Appalachian communities often have 1) higher rates of tobacco product use overall, 2) different use patterns that include more combusted tobacco products, and 3) different product availability in tobacco stores. It is therefore important to estimate any differential impact of proposed tobacco-product regulations in Appalachia. Using an Experimental Tobacco Marketplace (ETM) model where product availability is manipulated across groups and demand elasticity and substitution is measured across tobacco products, we will estimate the impact of regulating 1) nicotine content of combusted cigarettes, 2) menthol flavor restrictions in combustible cigarettes, and 3) flavor additive restrictions in non- combusted nicotine/tobacco products including ENDS. Across two aims, we will assess the impact of these three regulations within Appalachia (Aim 1) and the effect of rurality on impact of these proposed regulations in Appalachia (Aim 2).

摘要 - 项目3 我们的总体目标，反映了AppalTrust调查监管变化影响的综合主题 关于阿巴拉契亚肯塔基州烟草产品的使用是为了评估拟议的烟草产品法规的影响 使用过去几年我们开发和完善的行为经济方法来表征 在复杂的阿巴拉契亚肯塔基州尼古丁市场中消费烟草产品，多元化 服务不足的农村地区将大大受益于重点的烟草监管科学研究。这 项目主要属于影响分析的监管科学领域。 2009年，食物和毒品 行政管理（FDA）被授予规范烟草产品以使公共卫生受益的授权。在几年中 此后，FDA提出了可能受益于公共卫生的潜在监管行动，包括法规 混合香烟中的最大尼古丁含量以及限制燃烧和非燃料的口味 燃烧的烟草产品。估计任何拟议的监管行动的影响使 存在一个复杂的烟草市场，其中包含多种产品，这些产品是一个经济替代品 另一个和经常由制造商引入了新的烟草产品。此外，什么时候 与更多的城市，非阿帕拉奇社区相比，阿巴拉契亚粗糙的社区通常具有1）更高 烟草产品的使用率总体上使用，2）不同的使用模式，包括更多燃烧的烟草产品， 3）烟草商店中的不同产品可用性。因此，重要的是要估计任何差异影响 阿巴拉契亚州拟议的烟草产品法规。使用实验性烟草市场（ETM） 在各组之间操纵产品可用性的模型，并且需求弹性和替代是 通过烟草产品测量，我们将估计调节的影响1）燃烧的尼古丁含量 香烟，2）混合香烟中的精神病风味限制，3）非 - 燃烧的尼古丁/烟草产品，包括末端。在两个目标中，我们将评估这些影响的影响 阿巴拉契亚州内的三项法规（AIM 1）以及粗糙度对这些拟议法规在 阿巴拉契亚（AIM 2）。