AppalTRuST Project 3: Impact of proposed tobacco product rules in Appalachia on consumption and product switching with the Experimental Tobacco Marketplace

AppalTRuST 项目 3：阿巴拉契亚拟议烟草产品规则对实验烟草市场消费和产品转换的影响

• 批准号: 10665322
• 负责人: Mikhail Nikolaas Koffarnus
• 金额: $ 65.24万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-30 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10665322
• 关键词: Appalachian Region; Authorization documentation; Behavior; Biometry; Catchment Area; Cigarette; Cities; Communities; Community Outreach; Complex; Consumption; Data; Economics; Elasticity; Environment; Goals; Grant; Informatics; Manufacturer; Measures; Menthol; Methods; Modeling; Nicotine; Participant; Pattern; Policies; Price; Public Health; Randomized; Recommendation; Regulation; Research; Rural; Rural Appalachia; Rural Community; Sampling; Taxation; Tobacco; Tobacco use; United States Food and Drug Administration; Variant; abuse liability; authority; behavioral economics; combustible cigarette; design; falls; low nicotine content cigarette; nicotine user; patient engagement; peri-urban; prospective; recruit; rural area; rural underserved; rurality; tobacco products; tobacco regulation; tobacco regulatory science; urban area

ABSTRACT – Project 3 Our overall goal, reflecting AppalTRuST’s Integrative Theme of investigating the effects of regulatory changes on tobacco product use in Appalachian KY, is to assess the impact of proposed tobacco product regulations using behavioral economic methods that we have developed and refined in past years to characterize the consumption of tobacco products within the complex nicotine marketplace of Appalachian KY, a diverse and underserved rural region that would greatly benefit from focused tobacco regulatory science research. This project primarily falls under the Regulatory Scientific Domain of Impact Analysis. In 2009, the Food and Drug Administration (FDA) was granted authority to regulate tobacco products to benefit public health. In the years since, the FDA has proposed potential regulatory actions that may benefit public health, including regulating the maximum nicotine content in combustible cigarettes and restricting flavors of combusted and non- combusted tobacco products. Estimating the impact of any proposed regulatory action is complicated by the existence of a complex tobacco marketplace containing multiple products that are economic substitutes for one another and the frequent introduction of new tobacco products by manufacturers. Furthermore, when compared to more urban, non-Appalachian communities, rural Appalachian communities often have 1) higher rates of tobacco product use overall, 2) different use patterns that include more combusted tobacco products, and 3) different product availability in tobacco stores. It is therefore important to estimate any differential impact of proposed tobacco-product regulations in Appalachia. Using an Experimental Tobacco Marketplace (ETM) model where product availability is manipulated across groups and demand elasticity and substitution is measured across tobacco products, we will estimate the impact of regulating 1) nicotine content of combusted cigarettes, 2) menthol flavor restrictions in combustible cigarettes, and 3) flavor additive restrictions in non- combusted nicotine/tobacco products including ENDS. Across two aims, we will assess the impact of these three regulations within Appalachia (Aim 1) and the effect of rurality on impact of these proposed regulations in Appalachia (Aim 2).

摘要-项目3 我们的总体目标，反映了AppalTRuST调查监管变化影响的综合主题 关于烟草产品在阿巴拉契亚肯塔基州的使用，是为了评估拟议的烟草产品法规的影响 使用我们在过去几年中开发和改进的行为经济学方法来表征 在阿巴拉契亚肯塔基州复杂的尼古丁市场内消费烟草产品，这是一个多样化和 服务不足的农村地区将从有重点的烟草监管科学研究中受益匪浅。这 该项目主要属于影响分析的管理科学领域。2009年，美国食品药品监督管理局 美国食品和药物管理局(FDA)被授权对烟草产品进行监管，以造福公众健康。在过去的岁月里 自那以后，FDA提出了可能有利于公众健康的潜在监管行动，包括监管 可燃卷烟的最高尼古丁含量和可燃卷烟和非可燃卷烟的限制香味 燃烧的烟草产品。估计任何拟议的监管行动的影响是复杂的 存在一个复杂的烟草市场，其中包含多种产品，这些产品是一种产品的经济替代品 另一个原因是制造商频繁推出新的烟草产品。此外，当 与更多的城市、非阿巴拉契亚社区相比，阿巴拉契亚农村社区通常拥有更高的 烟草产品总体使用率，2)包括更多燃烧烟草产品的不同使用模式， 3)烟草商店的产品供应不同。因此，重要的是要估计任何不同的影响 阿巴拉契亚地区拟议的烟草产品法规。使用实验性的烟草市场(ETM) 产品可获得性跨组控制，需求弹性和替代性为 通过对烟草产品的衡量，我们将估计监管燃烧后的烟草中尼古丁含量的影响 香烟，2)可燃香烟中的薄荷醇风味限制，以及3)非可燃香烟中的香精添加剂限制 燃烧的尼古丁/烟草产品，包括烟头。在两个目标上，我们将评估这些目标的影响 阿巴拉契亚地区的三项规定(目标1)以及乡村对这些拟议规定在#年的影响 阿巴拉契亚(目标2)。