Metabolic/gas exchange system

代谢/气体交换系统

• 批准号: 10629673
• 负责人: KENNETH K KWONG
• 金额: $ 16.12万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-15 至 2024-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10629673
• 关键词: Area; Boston; Brain; Cardiovascular system; Clinical; Clinical Research; Devices; Diagnostic Imaging Program; Ensure; Equipment; Funding; Future; Gases; Image; Institution; Long COVID; Lung; Magnetic Resonance Imaging; Magnetoencephalography; Metabolic; Monitor; Physiological; Positron-Emission Tomography; Rehabilitation therapy; Request for Applications; Research; Research Subjects; Safety; System; biomedical imaging; imaging modality; imaging platform; optical imaging; pandemic disease; pulmonary function; research and development; software development; success; tool

PROJECT SUMMARY This application requests funding to purchase a Metabolic/Gas Exchange system. The state-of- the-art Metabolic Gas Exchange system is the only system with accessories made compatible with magnetic resonance imaging (MRI) to acquire a wide range of breath-by-breath gas exchange and pulmonary function parameters. In addition, a set of comprehensive vital monitoring tools will be equipped to ensure the safety of the research subjects and the needs of physiological recordings in different clinical and hardware/software development research at the Martinos Center, across different departments at MGH, as well as different institutions in the Boston area. The proposed Metabolic/Gas Exchange system is especially important to ensure the continuity of the existing funded projects and the synergistic research in the future. The system not only serves as a replacement of the existing equipment constructed with separate pieces of outdated devices that are nearly worn out but also provides a wider opportunity for synergizing research in the study of brain activity in association with pulmonary function and gas exchange. For example, one major area in the near future is mechanistic and clinical research for the potential upcoming rehabilitation pandemic of long COVID, which involves studying the interaction between the brain, pulmonary system, and cardiovascular system. The proposed Metabolic/Gas Exchange system will be located within the Athinoula A. Martinos Center for Biomedical Imaging, MGH. The Martinos Center has a renowned biomedical imaging program, consistently producing successes with imaging modalities such as MRI, magnetoencephalography (MEG), positron emission tomography (PET), and optical imaging. The proposed system will be fully utilized in the existing and future imaging research on this successful imaging platform for the users at Martinos Center and the other institutions in Boston.

项目摘要 本申请要求资助购买代谢/气体交换系统。国家- 最先进的代谢气体交换系统是唯一的系统与配件兼容， 磁共振成像（MRI），以获得广泛的呼吸-呼吸气体交换， 肺功能参数此外，一套全面的重要监测工具将 配备，以确保研究对象的安全和生理记录的需要， Martinos中心的不同临床和硬件/软件开发研究， MGH的部门，以及波士顿地区的不同机构。 建议的代谢/气体交换系统对于确保 现有的资助项目和未来的协同研究。该系统不仅作为 更换现有的设备，这些设备是由过时的设备组成的， 但也为大脑研究中的协同研究提供了更广泛的机会 与肺功能和气体交换相关的活性。例如， 不久的将来是针对潜在的即将到来的康复流行病的机制和临床研究 长期的COVID，其中包括研究大脑，肺系统和 心血管系统 拟定的代谢/气体交换系统将位于Athinoula A内。马蒂诺斯 麻省总医院生物医学影像中心。马蒂诺斯中心有一个著名的生物医学成像 计划，不断取得成功的成像模式，如MRI， 脑磁图（MEG）、正电子发射断层扫描（PET）和光学成像。的 建议的系统将充分利用现有的和未来的成像研究，这一成功的 为Martinos中心和波士顿其他机构的用户提供成像平台。