Administrative Core

行政核心 项目摘要 “默克尔细胞癌的免疫生物学和免疫治疗”P01的管理核心提供了 科学咨询委员会会议的总体指导和协调，以及行政、法规和 对三个项目和三个共享资源核心（生物统计学和生物信息学， 免疫表型分析和标本与数据）。行政核心将提供有效的组织 加快研究和促进计划项目组成部分之间的沟通的结构， 研究人员、科学界和患者群体。行政核心负责战略 计划，以及在执行地点之间的有效组织结构（弗雷德哈钦森癌症 研究中心，华盛顿大学和西雅图癌症护理联盟）。行政核心是 负责研究工作的协调和NIH资金的分配。该核心还将管理财政 计划项目的组成部分，包括重新分配资金，以优化整体功能和解决方案 以公平和公正的方式解决潜在的冲突，以最大限度地提高计划的进展。行政 核心负责沟通，包括通过以下方式传播与计划相关的信息： 电子邮件、GoToMeeting电话会议以及面对面会议。此外，核心将提供 通过维护与病人、医生和科学界的战略联系， merkelcell.org网站（每年有100，000名独立用户），与我们的MCC患者协调 倡导者，并组织MCC多中心利益集团年会。内核的使命 确保法规和行政合规性，包括向科学咨询委员会报告， NIH以及支持和维持项目和项目核心的最佳效率。

ADMINISTRATIVE CORE PROJECT SUMMARY The Administrative Core of the “Immunobiology and Immune Therapy for Merkel cell carcinoma” P01 provides overall direction, coordination of the Scientific Advisory Board meetings, as well as administrative, regulatory and fiscal oversight to the three Projects and the three Shared Resource Cores (Biostatistics & Bioinformatics, Immunophenotyping, and Specimen & Data). The Administrative Core will provide an effective organizational structure to expedite research and promote communication between Program Project components and investigators and the scientific and patient communities. The Administrative Core is responsible for strategic planning, as well as effective organizational structure among the performance sites (Fred Hutchinson Cancer Research Center, University of Washington, and Seattle Cancer Care Alliance). The Administrative Core is responsible for research effort coordination and allocation of NIH funds. This Core will also manage fiscal components of the Program Project including reallocation of funds to optimize overall function, and resolution of potential conflicts in a fair and equitable manner to maximize progress of the Program. The Administrative Core is responsible for communication including dissemination of information relevant to the Program via email, GoToMeeting teleconferences, as well as in-person meetings. In addition, The Core will provide strategic outreach to the patient, physician, and scientific communities through maintenance of the merkelcell.org website (which reaches 100,000 unique users each year), coordination with our MCC patient advocates, and organization of the MCC Multicenter Interest Group annual meeting. The mission of this Core is to ensure regulatory and administrative compliance including reporting to the Scientific Advisory Boards and NIH as well as to support and sustain optimal efficiency of the Projects and Cores of the Program.