Bio-Layer Interferometry (BLI) Octet R8

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Project Summary/Abstract This proposal requests funding for an Octet R8 to support NIH Institutional Development Award (IDeA) centers in the state of Nevada and NIH-funded researchers. A significant portion of the instrument time would be to address the needs of NIH-funded investigators across the campus via interdisciplinary collaborations and support between colleges of engineering, science, and medicine. The Octet R8 will also provide support for the Nevada INBRE, Integrative Neuroscience Center of Biomedical Research Excellence (COBRE) and the Cellular, Molecular Imaging Center funded by NIH. The Octet R8 will allow researchers to perform new types of biosensing, drug discovery, and diagnosis including protein-protein, protein-small molecule, protein nanoparticles, and protein-DNA interaction studies in real-time and high-throughput screening of potential therapeutics, and sensitive biomolecular sensing application.