Computer-facilitated Screening and Brief Intervention in pediatric primary care to reduce underage drinking: a large multi-site randomized trial (ADMIN SUPP: Special Interest)

儿科初级保健中计算机辅助筛查和简短干预以减少未成年人饮酒：一项大型多中心随机试验（ADMIN SUPP：特别兴趣）

• 批准号: 10675332
• 负责人: Sion Kim Harris
• 金额: $ 28.43万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-04-10 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10675332
• 关键词: Academy; Accounting; Address; Administrative Supplement; Adolescent; Age; American; Behavior; Childhood; Clinic; Communities; Computers; Early Diagnosis; Enrollment; Environment; Goals; Impairment; Intervention; Language; Light; Measures; Modification; Outcome; Parents; Patients; Pediatric Research; Pediatrics; Primary Health Care; Procedures; Randomized; Randomized Controlled Trials; Reporting; Research; Research Personnel; Risk; Sex Orientation; Sexual and Gender Minorities; Site; Social support; Substance Use Disorder; System; Testing; Visit; adolescent health; alcohol misuse; base; binge drinking; bullying; design; driving safety; effectiveness testing; health disparity; impaired driving performance; improved; interest; minority children; parent grant; peer; practice-based research network; primary care setting; randomized trial; recruit; research study; school environment; screening and brief intervention; sexual role; social health determinants; social influence; substance use; substance use prevention; transgender; treatment arm; treatment as usual; underage drinking reduction

PROJECT SUMMARY/ABSTRACT This is an administrative supplement in support of the parent grant (5R01AA027253), which allows modifications to be made to the study materials and procedures to address considerations for minoritized adolescent health disparities and the influences of social determinants of health on our study aims. The goal of the parent grant is to test the effectiveness of a promising computer-facilitated adolescent Screening and Brief Intervention (cSBI) system for delivery by pediatric primary care clinicians in a cluster-randomized controlled trial of patients ages 14-17 years with an upcoming annual well-visit who report unhealthy alcohol use or having ridden with an impaired driver in the past 12 months. Up to 40 pediatric primary clinicians across up to 10 practices are being recruited and randomized into either a Usual care or cSBI arm, and we expect at least 1,300 of their eligible patients will be enrolled. The parent study primary aims are to test the effect of cSBI on adolescents’ risk of heavy episodic drinking and on riding with an impaired driver/driving while impaired in the past 12 months. This trial is being conducted in the American Academy of Pediatrics’ Pediatric Research in Office Settings (PROS) national practice-based research network. This study is one of the largest pediatric trials to date of substance use screening and brief intervention in primary care settings. In this supplement, we seek to enhance understanding of disparities in substance use-related risk among adolescents who are sexual and gender minority (SGM). SGM adolescents are at greater risk of unhealthy substance use behaviors and substance use disorders compared to their non-SGM peers. Nonetheless, SGM adolescents have been underrepresented in primary care-based screening and brief intervention research studies aimed at early detection and prevention of substance use. Collaborating with researchers who have SGM expertise and with a community advisory board, we will develop recruitment materials that appeal to SGM adolescents in general pediatric clinic settings, as well as clinician guidance on SGM-friendly language and environment to enhance inclusion of SGM adolescents in the trial. We will add measures of sexual orientation and transgender status to more accurately identify SGM adolescents, and several measures accounting for social determinants of health that influence substance use risk (e.g., bullying, social support, school environment). The goal of adding these measures is to shed light on the role of SGM status and SGM-relevant social determinants of health exposure on substance use risk among adolescents in our study.

项目总结/摘要 这是一个行政补充，以支持家长赠款（5R01AA027253），它允许 修改研究材料和程序，以解决少数群体的考虑因素 青少年健康差异和健康的社会决定因素对我们研究目的的影响。的目标 家长补助金是为了测试一个有前途的计算机辅助青少年筛选和简报的有效性 在一项随机分组对照研究中，儿科初级保健临床医生使用cSBI系统进行分娩 在14 - 17岁的患者中进行的试验，这些患者报告了不健康的酒精使用， 在过去的12个月里与一名残疾司机一起骑车。最多40名儿科初级临床医生， 正在招募10个实践，并随机分配到患者护理或cSBI组，我们预计至少 将招募1，300名合格患者。母研究的主要目的是测试cSBI对 青少年的风险，大量的间歇性饮酒和乘坐与受损的司机/驾驶，而受损的， 过去12个月这项试验是在美国儿科学会的儿科研究中进行的， 办公室设置（PROS）国家实践为基础的研究网络。这项研究是最大的儿科研究之一， 迄今为止在初级保健机构进行的药物使用筛查和简短干预试验。在本补充中，我们 寻求提高对青少年中与药物使用有关的风险差异的认识， 性别少数群体（SGM）SGM青少年有更大的风险不健康的物质使用行为， 物质使用障碍相比，他们的非SGM同行。尽管如此，SGM青少年一直 在以初级保健为基础的筛查和旨在早期干预的简短干预研究中代表性不足 检测和预防药物使用。与拥有SGM专业知识的研究人员合作， 作为一个社区咨询委员会，我们将开发吸引一般SGM青少年的招聘材料 儿科诊所设置，以及临床医生对SGM友好的语言和环境的指导，以提高 将SGM青少年纳入试验。我们将增加性取向和变性人身份的措施， 更准确地识别SGM青少年，以及解释健康社会决定因素的几项措施 影响物质使用风险的因素（例如，欺凌、社会支持、学校环境）。添加这些的目的是 这些措施的目的是阐明SGM地位和SGM相关的健康暴露社会决定因素的作用 青少年药物使用风险的研究。