Core A: Administrative Core

核心A：行政核心

• 批准号: 10675113
• 负责人: RUTH R MONTGOMERY
• 金额: $ 41万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-02 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10675113
• 关键词: Address; Advanced Development; Advisory Committees; Aging; Atlases; Biological; Biology of Aging; Cell Aging; Cells; Collection; Communication; Communities; Consult; Consultations; Controlled Environment; Data; Data Analyses; Data Analytics; Data Coordinating Center; Data Storage and Retrieval; Decision Making; Development; Ensure; Funding; Future; Generations; Geroscience; Goals; Human; Immune; Immunologics; Inflammaging; Inflammation; Institution; Intellectual Property; Intramural Research Program; Investigation; Kinetics; Laboratory mice; Longevity; Lymphoid; Maps; Metabolic; Monitor; Mouse Strains; Mus; Organ; Participant; Pilot Projects; Procedures; Progress Reports; Publications; Quality Control; Reagent; Research; Research Personnel; Research Project Grants; Research Training; Resolution; Resources; Role; Site; Specimen; Standardization; Technology; Tissues; Transgenic Mice; United States National Institutes of Health; Visualization software; cost effective; data sharing; data visualization; experience; genetic manipulation; innovation; meetings; mouse model; new technology; novel; senescence; specific biomarkers; success; synergism; tissue mapping; tool

SUMMARY Core A An Administrative Core will coordinate and facilitate all activities within the U54 SenNet Murine Tissue Mapping Center (mTMC) Research Group. Core A will be headed by Drs. Dixit and Montgomery, who are NIH funded investigators and bring many years of experience at managing large collaborative research projects. This Core will be responsible for the overall organization, management, decision-making, and communication in the project, as well as utilization of institutional resources. The Administrative Core will provide oversight and consultation to each of the Cores to ensure that scientific objectives are met and that there is optimal utilization of resources. Specifically, the Administrative Core will: 1) monitor and assist each group so that their goals are achieved, and emergent problems are expeditiously addressed; 2) provide fiscal management and ensure cost-effective utilization of U54 resources; 3) ensure timely sharing of SOPs and data packages; 4) support collaborative activities and pilot studies; 5) promote the communication and dissemination of research and technology; and 6) organize the presentation and publication of data. This Core will also ensure data sharing, protection of intellectual property, and long-term data storage in coordination with the SenNet CODCC. Core A will have scientific input from both an Internal and External Advisory Committee and full partnership across the SenNet to advance development of the atlas. The Core Directors chair progress meetings and advisory committees to oversee progress and promote the success of the mTMC.

核心A 管理核心将协调和促进U 54 SenNet小鼠组织图谱内的所有活动 中心（mTMC）研究小组。核心A将由NIH资助的Diary博士和蒙哥马利博士领导 研究人员，并带来了多年的管理大型合作研究项目的经验。这一核心 负责项目的全面组织、管理、决策和沟通， 以及机构资源的利用。行政核心将提供监督和咨询 确保科学目标得以实现，资源得到最佳利用。 具体而言，行政核心将：1）监督和协助每个小组，以实现其目标， 迅速处理紧急问题; 2）提供财务管理，确保符合成本效益 利用U 54资源; 3）确保及时共享SOP和数据包; 4）支持协作 活动和试点研究; 5）促进研究和技术的交流和传播;以及6） 组织数据的展示和发布。该核心还将确保数据共享， 知识产权，以及与SenNet CODCC协调的长期数据存储。核心A将具有 来自内部和外部咨询委员会的科学投入以及整个SenNet的全面合作伙伴关系， 推进地图集的开发。核心主任主持进度会议和咨询委员会， 监督进展并促进mTMC的成功。