Training in Immunological Mechanisms
Training in Immunological Mechanisms
批准号:
10675443
负责人:
Michael Croft
金额:
$25.73万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
未结题
起止时间:
2016-08-01 至 2026-07-31
关键词:
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Abstract
This program will train postdoctoral research scientists in immunological mechanisms related to development
and treatment of Autoimmune, Inflammatory, and Infectious Disease, and Cancer. The program at La Jolla
Institute for Immunology (LJI) will involve 20 faculty members from LJI whose expertise is in immune cell
function that relates to diseases such as diabetes, inflammatory bowel disease, multiple sclerosis, asthma,
atherosclerosis, atopic dermatitis, dengue, HIV, cytomegalovirus, tuberculosis, ebola, and immuno-oncology.
Each faculty mentor is internationally recognized in the field of immunology or immunological disease and each
has substantial peer-reviewed research experience and track records. The program will be open to PhD, MD,
and MD/PhD scientists interested in basic and applied research of the immune system. The training program
will consist of a bench research laboratory experience of 12-24 months, under the close supervision of a
mentor or several mentors working on problems relevant to immunotherapy. The research backgrounds of the
faculty mentors are diverse, but with common themes centered on the biology of the primary cells of the
immune system, including T cells, B cells, NKT cells, macrophages, dendritic cells, neutrophils, and others.
The training program will then represent an interdisciplinary approach where each trainee is exposed to cutting
edge and state-of-the-art immunological techniques and systems for making fundamental and translational
discoveries of the immune system. Our current and past trainees have excellent records of research
accomplishments. New trainees will be recruited nationwide and efforts will be made to recruit and retain
exceptional minority, women, and disadvantaged candidates. Trainees will be chosen on the basis of their prior
academic performance, research experience, publications, interviews, and recommendations from supervisors.
Trainees will participate in institutional seminars, journal clubs, courses, and immunology conferences
designed to expand the breadth of their understanding of immunology and immunological disease. All trainees
will be instructed in the principles of responsible conduct of research and scientific integrity. The goals of the
program are to foster the development of well-rounded immunologists who can fill much needed academic
positions, who can compete and be successful in obtaining independent research grants, and who can
contribute to biotechnology and pharmaceutical approaches, aimed at treatment of immune-related diseases.
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DOI:
10.3390/ijms23179875
发表时间:
2022-08-30
期刊:
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子:
5.6
作者:
[Saigusa, Ryosuke, Vallejo, Jenifer, Gulati, Rishab, Suthahar, Sujit Silas Armstrong, Suryawanshi, Vasantika, Alimadadi, Ahmad, Makings, Jeffrey, Durant, Christopher P., Freuchet, Antoine, Roy, Payel, Ghosheh, Yanal, Pandori, William, Pattarabanjird, Tanyaporn, Drago, Fabrizio, Taylor, Angela, McNamara, Coleen A., Shemesh, Avishai, Lanier, Lewis L., Hedrick, Catherine C., Ley, Klaus]
通讯作者:
Ley, Klaus
DOI:
10.1016/j.jns.2022.120510
发表时间:
2023-01-15
期刊:
JOURNAL OF THE NEUROLOGICAL SCIENCES
影响因子:
4.4
作者:
[Williams, Gregory P., Muskat, Kaylin, Frazier, April, Xu, Yaqian, Mateus, Jose, Grifoni, Alba, Antunes, Ricardo da Silva, Weiskopf, Daniela, Amara, Amy W., Standaert, David G., Goldman, Jennifer G., Litvan, Irene, Alcalay, Roy N., Sulzer, David, Arlehamn, Cecilia S. Lindestam, Sette, Alessandro]
通讯作者:
Sette, Alessandro
DOI:
10.4049/jimmunol.1900245
发表时间:
2019-12-15
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
[Gaddis DE, Padgett LE, Wu R, Hedrick CC]
通讯作者:
Hedrick CC
Preparation of Whole Bone Marrow for Mass Cytometry Analysis of Neutrophil-lineage Cells.
制备全骨髓用于中性粒细胞谱系细胞的质量细胞计数分析。
DOI:
10.3791/59617
发表时间:
2019
期刊:
Journal of visualized experiments : JoVE
影响因子:
--
作者:
[Zhu,YanfangPeipei, Padgett,Lindsey, Dinh,HuyQ, Marcovecchio,Paola, Wu,Runpei, Hinz,Denise, Kim,Cheryl, Hedrick,CatherineC]
通讯作者:
Hedrick,CatherineC
DOI:
10.1038/s41556-023-01152-6
发表时间:
2023-06
期刊:
Nature cell biology
影响因子:
21.3
作者:
[]
通讯作者:
共 13 条
TWEAK and Skin Inflammation
-
批准号:10400699
-
项目类别:
-
资助金额:$39.2万
-
财政年份:2018
-
负责人:Michael Croft
-
依托单位:
A Treg cell-intrinsic CTLA4-PKC-eta signaling pathway mediating contact-dependent suppression of tumor immunity: A novel target for cancer immunotherapy
-
批准号:10531229
-
项目类别:
-
资助金额:$51.26万
-
财政年份:2018
-
负责人:Michael Croft
-
依托单位:
Immune Regulation by Deubiquitination
-
批准号:9982199
-
项目类别:
-
资助金额:$45.0万
-
财政年份:2018
-
负责人:Michael Croft
-
依托单位:
A Treg cell-intrinsic CTLA4-PKC-eta signaling pathway mediating contact-dependent suppression of tumor immunity: A novel target for cancer immunotherapy
-
批准号:10053328
-
项目类别:
-
资助金额:$52.31万
-
财政年份:2018
-
负责人:Michael Croft
-
依托单位:
TWEAK and Skin Inflammation
-
批准号:9910059
-
项目类别:
-
资助金额:$39.6万
-
财政年份:2018
-
负责人:Michael Croft
-
依托单位:
A Treg cell-intrinsic CTLA4-PKC-eta signaling pathway mediating contact-dependent suppression of tumor immunity: A novel target for cancer immunotherapy
-
批准号:10310411
-
项目类别:
-
资助金额:$51.26万
-
财政年份:2018
-
负责人:Michael Croft
-
依托单位:
TWEAK and Skin Inflammation
-
批准号:10152528
-
项目类别:
-
资助金额:$38.41万
-
财政年份:2018
-
负责人:Michael Croft
-
依托单位:
Immune Regulation by Deubiquitination
-
批准号:9788250
-
项目类别:
-
资助金额:$45.0万
-
财政年份:2018
-
负责人:Michael Croft
-
依托单位:
Training in Immunological Mechanisms
-
批准号:9321444
-
项目类别:
-
资助金额:$33.47万
-
财政年份:2016
-
负责人:Michael Croft
-
依托单位:
Training in Immunological Mechanisms
-
批准号:10269804
-
项目类别:
-
资助金额:$37.53万
-
财政年份:2016
-
负责人:Michael Croft
-
依托单位:
Training in Immunological Mechanisms
-
批准号:10458735
-
项目类别:
-
资助金额:$33.27万
-
财政年份:2016
-
负责人:Michael Croft
-
依托单位:
Novel PTPRD interaction Controlling T cell Responsiveness
-
批准号:9077779
-
项目类别:
-
资助金额:$26.55万
-
财政年份:2016
-
负责人:Michael Croft
-
依托单位:
Structural Characterization of 4-1BB-Galectin-9 Complexes
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批准号:8679808
-
项目类别:
-
资助金额:$8.85万
-
财政年份:2014
-
负责人:Michael Croft
-
依托单位:
Control of Airway Tolerance
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批准号:8577804
-
项目类别:
-
资助金额:$41.6万
-
财政年份:2013
-
负责人:Michael Croft
-
依托单位:
Control of Airway Tolerance
-
批准号:8661698
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项目类别:
-
资助金额:$44.25万
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财政年份:2013
-
负责人:Michael Croft
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依托单位:
Novel costimulatory pathways required for T cell regulation
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批准号:8495230
-
项目类别:
-
资助金额:$43.81万
-
财政年份:2013
-
负责人:Michael Croft
-
依托单位:
Control of Airway Tolerance
-
批准号:9267076
-
项目类别:
-
资助金额:$44.25万
-
财政年份:2013
-
负责人:Michael Croft
-
依托单位:
Control of Airway Tolerance
-
批准号:9054041
-
项目类别:
-
资助金额:$44.25万
-
财政年份:2013
-
负责人:Michael Croft
-
依托单位:
Control of Airway Tolerance
-
批准号:8839196
-
项目类别:
-
资助金额:$44.25万
-
财政年份:2013
-
负责人:Michael Croft
-
依托单位:
Novel costimulatory pathways required for T cell regulation
-
批准号:8377924
-
项目类别:
-
资助金额:$46.61万
-
财政年份:2012
-
负责人:Michael Croft
-
依托单位:
海外基金