Childrens' of Mississippi Neonatal Research Group

这项申请有力地支持了密西西比州唯一的学术第四级新生儿设施，即 密西西比大学医学中心密西西比州儿童新生儿重症监护病房(NICU) S被NICHD新生儿研究网络提名为临床中心。我们致力于 改善密西西比州儿童的生活，提供特殊的患者护理，培训下一代 医疗保健提供者，并从事创新研究，以实现UMMC改善的愿景 密西西比州的健康结果和消除医疗保健差距。新生儿科的研究人员 通过执行创新、明确、严谨且可复制的单站点和多站点翻译做出贡献 临床和社区干预研究的重点是改善新生儿健康以缩小差距 “从板凳到床边到乡村”的研究。 UMMC的新生儿中心处于非常有利的地位，可以被选中，原因如下。1) 我们的服务对象是风险很高、服务不足的人群，其中大多数人的社会经济地位和公众地位都很低。 面向健康的种族/少数民族代表性较高的城乡保险 差距。2)密西西比州的母亲高血压、先兆子痫、肥胖、 代谢紊乱、早产、低出生体重和先天相关的行为障碍，例如 美国的自闭症。3)UMMC的母婴保健中心，这是唯一的 该州先进的胎儿护理机构，每年管理约3000次分娩，其中75%被认为是 风险很高。4)每年约有1000名NICU入院，其中近160人出生不到29周 怀孕，大约70%是先天的。5)新生儿医学部有一个组织严密的临床 具有参与多中心NIH的成功记录的研究基础设施，行业赞助， 以及由研究人员发起的新生儿临床试验。6)该司一直是研究程度最高的 在多个多中心临床试验中招募受试者。这一成功归功于强有力的研究 文化和独特的全天候专职研究协调员制度，包括事后 工作时间和周末。这是我们节目的一大优势。7)该机构保持长期的- 常备的多学科新生儿跟踪计划，服务于整个州。8)新生儿科 医学一直得到机构的支持。它有着悠久的合作历史， 拥有NIH资助项目的其他机构中心/部门。 如果被选中，我们将完全致力于参与所有网络学习，除非他们没有 相关符合条件的人口。我们同意将网络研究优先于其他研究，包括其他NIH- 资助的研究，用于我们中心的学科招聘。

This application strongly supports the Mississippi state's only academic Level IV newborn facility, the Children's of Mississippi Newborn Intensive Care Unit (NICU) at the University of Mississippi Medical Center (UMMC)'s candidacy as a clinical center by the NICHD Neonatal Research Network (NRN). We work to improve the life of Mississippi children by providing exceptional patient care, training the next generation of healthcare providers, and engaging in innovative research to achieve the vision of UMMC to improve Mississippian's health outcomes and eliminate health care disparities. Researchers in the newborn division are contributing by performing innovative, definitive, rigorous, and reproducible translation, single and multi-site clinical, and community interventions research focused on improving newborn health to reduce the gap between “bench to bedside to countryside” research. The newborn center at the UMMC is exceptionally well positioned to be selected for the following reasons. 1) We serve a very high-risk and underserved population, the majority with low socioeconomic status and public insurance from urban and rural areas with high representation of racial/ethnic minorities facing health disparities. 2) Mississippi has some of the highest rates of maternal hypertension, preeclampsia, obesity, metabolic disorders, preterm birth, low birth weight, and congenitally linked behavioral disorders, such as autism in the USA. 3) The Center for Maternal and Fetal Care at UMMC, the only quaternary center for advanced fetal care in the state, manages around 3,000 deliveries each year, of which 75% are considered high risk. 4) About 1000 NICU admissions per year, of which almost 160 are born less than 29 weeks of gestation, and about 70% are inborn. 5) The Division of Newborn Medicine has a well-organized clinical research infrastructure with a successful track record of participation in multi-center NIH, industry-sponsored, and investigator-initiated clinical trials in newborns. 6) The Division has consistently been the highest study subject recruiting site in many multi-center clinical trials. This success is attributable to the strong research culture and a unique system of round-the-clock availability of dedicated research coordinators, including after- hours and weekends. This is an exceptional strength of our program. 7) The institution maintains a long- standing multidisciplinary Newborn Follow-up Program that serves the entire state. 8) The Division of Newborn Medicine has consistently received Institutional support. It has a long-standing history of collaboration with other institutional centers/departments with NIH-funded programs. If selected, we will be fully committed to participating in all Network studies unless they do not have the relevant eligible population. We agree to prioritize Network studies over other studies, including other NIH- funded studies, for subject recruitment at our center.