A Training Development Plan for HIV-associated Behavioural Medicine

项目说明/摘要 南非的艾滋病毒负担是世界上最大的，估计有820万人携带艾滋病毒(PWH) 在乡下。艾滋病毒流行是由生物、心理和社会因素的复杂相互作用推动的，而威斯康星病毒 高共病与常见精神障碍(CMD)-一些估计表明，五分之一的PWH 表现出抑郁、创伤后应激障碍或药物使用障碍的症状。这个 HIV和CMD的协同应激在整个HIV护理级联中具有显著的不利影响，最值得注意的是 关于坚持抗逆转录病毒治疗、保留艾滋病毒护理和病毒抑制。为了解决这些问题， 艾滋病毒精神健康研究单位(HIV MHU)进行了由美国国立卫生研究院资助的描述性和干预试验 经过十多年的研究，该股在#年开发了一个新的硕士学位课程 行为医学--南非的一个新兴领域。在UCT的研究和培训期间， 艾滋病毒和精神障碍的交集稳步增长，这些要素需要明确的凝聚力和战略 方向。具体地说，拟议的培训方案打算利用现有的研究方案 HIV MHU建设艾滋病毒相关行为医学方面的研究培训能力。为期两年的规划拨款 将使我们能够记录和分析联合技术大学和其他南非国家的现有研究和培训能力 大学在艾滋病毒相关行为医学方面的研究，以确定差距和需求。此外，通过协作 与合作机构的关系，我们的目标是建立一个组织结构，以支持 Fogarty D43申请，并确定UCT潜在的实习生候选人，这些候选人可以被招募参加 D43 Fogarty培训计划中的行为医学。在赠款期间，我们的目标是巩固 我们在该单位内的行为医学项目，更广泛的大学，以及我们的国际合作者， 最终为新的临床医生群提供一套硕士、博士和博士后培训- 科学家，以及基础科学家和社会科学家。虽然到目前为止我们的研究已经带来了艾滋病毒的改善 治疗依从性、病毒抑制和精神健康结果，行为医学是一种新兴的和 南非不断演变的油田。到目前为止，南非还没有建立起行为医学项目 重点关注艾滋病毒、精神障碍和行为。建议的规划拨款将有助建立 南非和非洲大陆的油田。

Project Description/Abstract South Africa has the largest HIV burden in the world, with an estimated 8.2 million people living with HIV (PWH) in the country. The HIV epidemic is driven by a complex interaction of biopsychosocial factors, and PWH have high comorbidity with common mental disorders (CMD) – some estimates indicate that one in five PWH demonstrate symptomology for depression, post-traumatic stress disorder, or substance use disorders. The synergistic stress of HIV and CMD has significant adverse impacts across the HIV care-cascade, most notably on adherence to antiretroviral therapy, retention in HIV care, and viral suppression. To address these concerns, the HIV Mental Health Research Unit (HIV MHU) has conducted NIH-funded descriptive and intervention trial research for more than a decade, which resulted in the Unit developing a new master’s degree program in Behavioural Medicine – a novel and emerging field in South Africa. While research and training at UCT at the intersection of HIV and mental disorders has grown steadily, these elements require clear cohesion and strategic direction. Specifically, the proposed training programme intends to leverage existing research programs in the HIV MHU to build research training capacity in HIV-associated behavioural medicine. A two-year planning grant will allow us to document and analyse the existing research and training capacity at UCT and other South African universities in HIV-associated behavioural medicine to define gaps and needs. Moreover, through collaborative relationships with partnering institutions, we aim to establish an organisational structure that would support a Fogarty D43 application and identify potential trainee candidates at UCT that could be recruited for training in behavioural medicine within the D43 Fogarty training program. During the grant period, we aim to consolidate our behavioural medicine program within the Unit, the wider University, and with our international collaborators, to ultimately offer a suite of master’s, doctoral and post-doctoral training to a new cohort of both clinician- scientists, as well as basic and social scientists. While our research to date has led to improvements in HIV treatment adherence, viral suppression, and mental health outcomes, behavioural medicine is an emerging and evolving field in South Africa. To date, there are no established behavioural medicine programs in South Africa that focus on HIV, mental disorders, and behaviour. The proposed planning grant will facilitate establishing the field in South Africa and the African continent.