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Administrative and Coordinating Core

行政协调核心

基本信息

批准号：
10689735
负责人：
MARGARET M MADELEINE
金额：
$ 32.91万
依托单位：
FRED HUTCHINSON CANCER CENTER
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-18 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10689735
关键词：
Acceleration Accountability Adoption Advocate Biological Assay CLC Gene Cancer Burden Caribbean region Cessation of life Child Clinical Clinical Services Clinical Trials Communication Communities Country Credentialing Data Dominican Republic Fostering Goals Grant Guidelines HIV Heart Human Papilloma Virus-Related Malignant Neoplasm Human Papillomavirus Human papilloma virus infection Income Information Dissemination Infrastructure Institution International Interruption Laboratories Laboratory Procedures Latin American Lead Leadership Lesion Malignant neoplasm of cervix uteri Methods Modeling Monitor Outcome Paper Periodicals Persons Peru Policies Population Preventative vaccination Prevention Primary Prevention Problem Solving Productivity Protocols documentation Publications Publishing Qualifying Quality Control Records Reporting Research Research Personnel Resources Risk Safety Schedule Science Scientific Advances and Accomplishments Secondary Prevention Services Site Structure Training Translating Triage Update Vaccination Woman Work cancer prevention cancer risk cervical cancer prevention co-clinical trial data management experience human subject improved meetings member novel strategies participant safety patient safety premalignant prevent recruit screening skills training success tertiary prevention tool

项目摘要

The overarching goal of the Administrative and Coordinating Core (ACC) is to provide effective leadership to optimize the successful accomplishment of the scientific aims of the Cervical Cancer Prevention Partnership (C2P2) Center in Peru and the Dominican Republic. The management team for the ACC includes three investigators: a Peru-based investigator, Dr. Robinson Cabello, MPI, and two Seattle-based investigators, Dr. Duerr (MPI and Co-Chair Trial 1) and Dr. Madeleine (Contact MPI, Co-Investigator Trials 2 and 3). Together they will provide scientific direction, enhance productivity, liaise with the NCI, and monitor safety, quality, recruitment, and progress toward each of the Aims of the Clinical Trials and service Cores. The Aims of the ACC are as follows: Aim 1 of the ACC is to organize the C2P2 Center by distributing responsibility and accountability throughout the C2P2 Center. The ACC will implement the Triple C (Communication, Cooperation and Coordination) model of project management. This organizational approach will be grounded in meeting regional needs and in respect for working with LAC partners who will lead and sustain the cuttingedge changes we develop together through integrated and interdisciplinary team science. Aim 2 is to facilitate communication and scheduling at all levels of the partnership. The ACC will foster high-level and bidirectional coordination and cooperation directly with unit leaders (Clinical Trial Co-Chairs and service Core Leaders) across the C2P2 Center (i.e., Core teams, Clinical Trial teams, institutions), and with external advisors (i.e., External Scientific Advisory Group and the cross-cutting Partnership Center Coordinating Committee). Aim 3 of the ACC is to lead all trial monitoring and regulatory coordination activities with the assistance of the Data Coordinating Core. The first priority of the ACC is patient safety at both trial sties. Aim 4 of the ACC will provide training and dissemination of findings. The ACC will administratively support the Clinical Trial Co-Chairs through cross-institutional training as needed to refine laboratory assay quality control, data management skills training, and streamlined organizational infrastructure building that will enhance the success of the matrixed partnership. All trial findings will be disseminated through published papers and presentations in the region and at international meetings of policy and guideline makers who will be able to use our trial findings to accelerate progress toward elimination of cervical cancer through prevention. The ACC will provide leadership to accomplish the overall scientific goal of the C2P2 Center to improve the quality and efficiency of cervical cancer prevention in the region.

行政和协调核心（行政协调会）的首要目标是提供有效的领导