SBIR TOPIC 112, FAST-TRACK, INTRAMYOCARDIAL SUTURE ANNULOPLASTY SYSTEM ("MIRTH" AND "SCIMITAR" DEVICES)

NHLBI开发了静脉内间质栓（MIRTH）心肌壁内约束术和相关的冠状窦缝合术，并通过心肌间质导航进行二尖瓣和三尖瓣环复位术（simitar），通过心脏肌肉间质导航进入心脏静脉，完成单瓣和双瓣环成形术。临床评估将需要开发类似的专用MIRTH和SCIMITAR装置。该合同旨在支持经导管MIRTH和“弯刀”系统的开发和商业化。

NHLBI has developed the Myocardial Intramural Restraint by endovenous interstitial teTHer (MIRTH) procedure and the related Suture via Coronary sinus with Interstitial myocardial navigation for MItral and Tricuspid Annular Reduction (SCIMITAR) procedure to accomplish single- and dual-valve annuloplasty via interstitial navigation of heart muscles entered through heart veins. Clinical evaluation will require the development of purpose-built MIRTH and SCIMITAR devices, which are similar. The contract aims to support the development and commercialization of transcatheter MIRTH and SCIMITAR system.