SBIR TOPIC 112, FAST-TRACK, INTRAMYOCARDIAL SUTURE ANNULOPLASTY SYSTEM ("MIRTH" AND "SCIMITAR" DEVICES)

NHLBI已开发出静脉内间质性结扎（MIRTH）手术的心肌壁内限制和相关的经冠状窦缝合（带间质性心肌导航），用于二尖瓣和三尖瓣环缩小术（SCIMITAR），以通过经心脏静脉进入的心肌间质性导航完成单瓣膜和双瓣膜瓣环成形术。临床评价将需要开发类似的专用MIRTH和SCIMITAR器械。该合同旨在支持经导管MIRTH和SCIMITAR系统的开发和商业化。

NHLBI has developed the Myocardial Intramural Restraint by endovenous interstitial teTHer (MIRTH) procedure and the related Suture via Coronary sinus with Interstitial myocardial navigation for MItral and Tricuspid Annular Reduction (SCIMITAR) procedure to accomplish single- and dual-valve annuloplasty via interstitial navigation of heart muscles entered through heart veins. Clinical evaluation will require the development of purpose-built MIRTH and SCIMITAR devices, which are similar. The contract aims to support the development and commercialization of transcatheter MIRTH and SCIMITAR system.